Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Keratin 23 (Histone deacetylase inducible)

Gene

KRT23

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Keratin 23 (Histone deacetylase inducible)Imported
Gene namesi
Name:KRT23Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Intermediate filamentUniRule annotationSAAS annotation, KeratinImported

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134914537.

PTM / Processingi

Proteomic databases

PaxDbiQ8TC04.
PeptideAtlasiQ8TC04.
PRIDEiQ8TC04.

Expressioni

Gene expression databases

GenevisibleiQ8TC04. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000209718.

Structurei

3D structure databases

ProteinModelPortaliQ8TC04.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili76 – 11035Sequence analysisAdd
BLAST
Coiled coili168 – 20235Sequence analysisAdd
BLAST
Coiled coili326 – 35732Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the intermediate filament family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IK9C. Eukaryota.
ENOG4111DWD. LUCA.
HOVERGENiHBG013015.
KOiK07604.

Family and domain databases

InterProiIPR001664. IF.
IPR018039. Intermediate_filament_CS.
IPR002957. Keratin_I.
[Graphical view]
PANTHERiPTHR23239. PTHR23239. 1 hit.
PfamiPF00038. Filament. 1 hit.
[Graphical view]
PRINTSiPR01248. TYPE1KERATIN.
SMARTiSM01391. Filament. 1 hit.
[Graphical view]
PROSITEiPS00226. IF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8TC04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSGHSFSQT PSASFHGAGG GWGRPRSFPR APTVHGGAGG ARISLSFTTR
60 70 80 90 100
SCPPPGGSWG SGRSSPLLGG NGKATMQNLN DRLASYVEKV RALEEANMKL
110 120 130 140 150
ESRILKWHQQ RDPGSKKDYS QYEENITHLQ EQIVDGKMTN AQIILLIDNA
160 170 180 190 200
RMAVDDFNLK YENEHSFKKD LEIEVEGLRR TLDNLTIVTT DLEQEVEGMR
210 220 230 240 250
KELILMKKHH EQEMEKHHVP SDFNVNVKVD TGPREDLIKV LEDMRQEYEL
260 270 280 290 300
IIKKKHRDLD TWYKEQSAAM SQEAASPATV QSRQGDIHEL KRTFQALEID
310 320 330 340 350
LQTQYSTKSA LENMLSETQS RYSCKLQDMQ EIISHYEEEL TQLRHELERQ
360 370 380 390 400
NNEYQVLLGI KTHLEKEITT YRRLLEGESE GTREESKSSM KVFATPKIKA
410 420
ITQETINGRL VLCQVNEIQK HA
Length:422
Mass (Da):48,177
Last modified:June 1, 2002 - v1
Checksum:i3A67594684E2DE4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028356 mRNA. Translation: AAH28356.1.
RefSeqiNP_056330.3. NM_015515.4.
UniGeneiHs.9029.

Genome annotation databases

GeneIDi25984.
KEGGihsa:25984.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC028356 mRNA. Translation: AAH28356.1.
RefSeqiNP_056330.3. NM_015515.4.
UniGeneiHs.9029.

3D structure databases

ProteinModelPortaliQ8TC04.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000209718.

Proteomic databases

PaxDbiQ8TC04.
PeptideAtlasiQ8TC04.
PRIDEiQ8TC04.

Protocols and materials databases

DNASUi25984.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi25984.
KEGGihsa:25984.

Organism-specific databases

CTDi25984.
PharmGKBiPA134914537.

Phylogenomic databases

eggNOGiENOG410IK9C. Eukaryota.
ENOG4111DWD. LUCA.
HOVERGENiHBG013015.
KOiK07604.

Miscellaneous databases

ChiTaRSiKRT23. human.
GenomeRNAii25984.

Gene expression databases

GenevisibleiQ8TC04. HS.

Family and domain databases

InterProiIPR001664. IF.
IPR018039. Intermediate_filament_CS.
IPR002957. Keratin_I.
[Graphical view]
PANTHERiPTHR23239. PTHR23239. 1 hit.
PfamiPF00038. Filament. 1 hit.
[Graphical view]
PRINTSiPR01248. TYPE1KERATIN.
SMARTiSM01391. Filament. 1 hit.
[Graphical view]
PROSITEiPS00226. IF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8TC04_HUMAN
AccessioniPrimary (citable) accession number: Q8TC04
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.