Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

LAMB1 protein

Gene

LAMB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
LAMB1 proteinImported
Gene namesi
Name:LAMB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30275.

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ8TAS6.
PeptideAtlasiQ8TAS6.
PRIDEiQ8TAS6.

Expressioni

Gene expression databases

GenevisibleiQ8TAS6. HS.

Interactioni

Protein-protein interaction databases

IntActiQ8TAS6. 3 interactions.
STRINGi9606.ENSP00000222399.

Structurei

3D structure databases

ProteinModelPortaliQ8TAS6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 6464Laminin IV type BInterPro annotationAdd
BLAST
Domaini70 – 11748Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini118 – 16346Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini164 – 21350Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini214 – 27259Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini273 – 32452Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini325 – 38056Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini381 – 42848Laminin EGF-likeInterPro annotationAdd
BLAST
Domaini429 – 47547Laminin EGF-likeInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili575 – 60935Sequence analysisAdd
BLAST
Coiled coili783 – 81028Sequence analysisAdd
BLAST
Coiled coili858 – 88528Sequence analysisAdd
BLAST
Coiled coili889 – 93042Sequence analysisAdd
BLAST
Coiled coili938 – 96528Sequence analysisAdd
BLAST
Coiled coili995 – 107177Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG0994. Eukaryota.
ENOG410XPEG. LUCA.
HOGENOMiHOG000007552.
HOVERGENiHBG052301.
KOiK05636.

Family and domain databases

InterProiIPR000742. EGF-like_dom.
IPR002049. Laminin_EGF.
IPR013015. Laminin_IV_B.
IPR009053. Prefoldin.
[Graphical view]
PfamiPF00053. Laminin_EGF. 8 hits.
[Graphical view]
SMARTiSM00181. EGF. 8 hits.
SM00180. EGF_Lam. 8 hits.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
PROSITEiPS01248. EGF_LAM_1. 7 hits.
PS50027. EGF_LAM_2. 8 hits.
PS51116. LAMININ_IVB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q8TAS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
LVLMPYCKSL DIFTVGGSGD GVVTNSAWET FQRYRCLENS RSVVKTPMTD
60 70 80 90 100
VCRNIIFSIS ALLHQTGLAC ECDPQGSLSS VCDPNGGQCQ CRPNVVGRTC
110 120 130 140 150
NRCAPGTFGF GPSGCKPCEC HLQGSVNAFC NPVTGQCHCF QGVYARQCDR
160 170 180 190 200
CLPGHWGFPS CQPCQCNGHA DDCDPVTGEC LNCQDYTMGH NCERCLAGYY
210 220 230 240 250
GDPIIGSGDH CRPCPCPDGP DSGRQFARSC YQDPVTLQLA CVCDPGYIGS
260 270 280 290 300
RCDDCASGYF GNPSEVGGSC QPCQCHNNID TTDPEACDKE TGRCLKCLYH
310 320 330 340 350
TEGEHCQFCR FGYYGDALQQ DCRKCVCNYL GTVQEHCNGS DCQCDKATGQ
360 370 380 390 400
CLCLPNVIGQ NCDRCAPNTW QLASGTGCDP CNCNAAHSFG PSCNEFTGQC
410 420 430 440 450
QCMPGFGGRT CSECQELFWG DPDVECRACD CDPRGIETPQ CDQSTGQCVC
460 470 480 490 500
VEGVEGPRCD KCTRGYSGVF PDCTPCHQCF ALWDVIIAEL TNRTHRFLEK
510 520 530 540 550
AKALKISGVI GPYRETVDSV ERKVSEIKDI LAQSPAAEPL KNIGNLFEEA
560 570 580 590 600
EKLIKDVTEM MAQVEVKLSD TTSQSNSTAK ELDSLQTEAE SLDNTVKELA
610 620 630 640 650
EQLEFIKNSD IRGALDSITK YFQMSLEAEE RVNASTTEPN STVEQSALMR
660 670 680 690 700
DRVEDVMMER ESQFKEKQEE QARLLYELAG KLQSLDLSAA AEMTCGTPPG
710 720 730 740 750
ASCSETECGG PNCRTDEGER KCGGPGCGGL VTVAHNAWQK AMDLDQDVLS
760 770 780 790 800
ALAEVEQLSK MVSEAKLRAD EAKQSAEDIL LKTNATKEKM DKSNEELRNL
810 820 830 840 850
IKQIRNFLTQ DSADLDSIEA VANEVLKMEM PSTPQQLQNL TEDIRERVES
860 870 880 890 900
LSQVEVILQH SAADIARAEM LLEEAKRASK SATDVKVTAD MVKEALEEAE
910 920 930 940 950
KAQVAAEKAI KQADEDIQGT QNLLTSIESE TAASEETLFN ASQRISELER
960 970 980 990 1000
NVEELKRKAA QNSGEAEYIE KVVYTVKQSA EDVKKTLDGE LDEKYKKVEN
1010 1020 1030 1040 1050
LIAKKTEESA DARRKAEMLQ NEAKTLLAQA NSKLQLLKDL ERKYEDNQRY
1060 1070 1080
LEDKAQELAR LEGEVRSLLK DISQKVAVYS TCL
Length:1,083
Mass (Da):118,913
Last modified:March 1, 2004 - v2
Checksum:i80F48466F457C222
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC026018 mRNA. Translation: AAH26018.2.
RefSeqiNP_002282.2. NM_002291.2.
UniGeneiHs.650585.

Genome annotation databases

GeneIDi3912.
KEGGihsa:3912.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC026018 mRNA. Translation: AAH26018.2.
RefSeqiNP_002282.2. NM_002291.2.
UniGeneiHs.650585.

3D structure databases

ProteinModelPortaliQ8TAS6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ8TAS6. 3 interactions.
STRINGi9606.ENSP00000222399.

Proteomic databases

PaxDbiQ8TAS6.
PeptideAtlasiQ8TAS6.
PRIDEiQ8TAS6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3912.
KEGGihsa:3912.

Organism-specific databases

CTDi3912.
PharmGKBiPA30275.

Phylogenomic databases

eggNOGiKOG0994. Eukaryota.
ENOG410XPEG. LUCA.
HOGENOMiHOG000007552.
HOVERGENiHBG052301.
KOiK05636.

Miscellaneous databases

ChiTaRSiLAMB1. human.
GenomeRNAii3912.

Gene expression databases

GenevisibleiQ8TAS6. HS.

Family and domain databases

InterProiIPR000742. EGF-like_dom.
IPR002049. Laminin_EGF.
IPR013015. Laminin_IV_B.
IPR009053. Prefoldin.
[Graphical view]
PfamiPF00053. Laminin_EGF. 8 hits.
[Graphical view]
SMARTiSM00181. EGF. 8 hits.
SM00180. EGF_Lam. 8 hits.
[Graphical view]
SUPFAMiSSF46579. SSF46579. 1 hit.
PROSITEiPS01248. EGF_LAM_1. 7 hits.
PS50027. EGF_LAM_2. 8 hits.
PS51116. LAMININ_IVB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ8TAS6_HUMAN
AccessioniPrimary (citable) accession number: Q8TAS6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: March 1, 2004
Last modified: July 6, 2016
This is version 82 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.