Unreviewed, UniProtKB/TrEMBL Q8TAN2 (Q8TAN2_HUMAN)

Names and origin

Protein names

Submitted name:
    Frizzled homolog 9 (Drosophila) EMBL AAH26333.1

Gene names

Name:

FZD9 EMBL AAH26333.1

Organism

Homo sapiens (Human) EMBL AAH26333.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	591 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 FZ (frizzled) domain.

Ontologies

Keywords
Biological process	Wnt signaling pathway Spearmint SPM017981
Cellular component	Membrane
Domain	Transmembrane Spearmint SPM000539
Molecular function	Developmental protein Spearmint SPM000539 G-protein coupled receptor Spearmint SPM000539 Receptor Transducer
Gene Ontology (GO)
Biological process	G-protein coupled receptor protein signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW Wnt receptor signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW learning or memory Inferred from electronic annotation. Source: Compara neuroblast proliferation Inferred from electronic annotation. Source: Compara
Cellular component	filopodium membrane Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW perinuclear region of cytoplasm Inferred from electronic annotation. Source: Compara
Molecular function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW Wnt receptor activity Inferred from electronic annotation. Source: Compara non-G-protein coupled 7TM receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8TAN2-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 9E341E2E33F70C4C	FASTA	591	64,519
	10 20 30 40 50 60 MAVAPLRGAL LLWQLLAAGG AALEIGRFDP ERGRGAAPCQ AVEIPMCRGI GYNLTRMPNL 70 80 90 100 110 120 LGHTSQGEAA AELAEFAPLV QYGCHSHLRF FLCSLYAPMC TDQVSTPIPA CRPMCEQARL 130 140 150 160 170 180 RCAPIMEQFN FGWPDSLDCA RLPTRNDPHA LCMEAPENAT AGPAEPHKGL GMLPVAPRPA 190 200 210 220 230 240 RPPGDLGPGA GGSGTCENRE KFQYVEKSRS CAPRCGPGVE VFWSRRDKDF ALVWMAVWSA 250 260 270 280 290 300 LCFFSTAFTV LTFLLEPHRF QYPERPIIFL SMCYNVYSLA FLIRAVAGAQ SVACDQEAGA 310 320 330 340 350 360 LYVIQEGLEN TGCTLVFLLL YYFGMASSLW WVVLTLTWFL AAGKKWGHEA IEAHGSYFHM 370 380 390 400 410 420 AAWGLPALKT IVILTLRKVA GDELTGLCYV ASTDAAALTG FVLVPLSGYL VLGSSFLLTG 430 440 450 460 470 480 FVALFHIRKI MKTGGTNTEK LEKLMVKVGV FSILYTVPAT CVIVCYVYER LNMDFWRLRA 490 500 510 520 530 540 TEQPCAAAAG PGGRRDCSLP GGSVPTVAVF MLKIFMSLVV GITNGVWVWS SKTFQTWQSL 550 560 570 580 590 CYRKIAAGRA RAKACHAPGS YGRGTHCHYK APTVVLHMTK TDPSLENPTH L

References

[1]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAH26333.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC026333 mRNA. Translation: AAH26333.1.
IPI	IPI00020230.
UniGene	Hs.647029
3D structure databases
HSSP	HSSP built from PDB template 1IJY based on UniProtKB Q61091.
SMR	Q8TAN2. Positions 38-155.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8TAN2. 1 interaction.
STRING	Q8TAN2.
Genome annotation databases
Ensembl	ENST00000344575; ENSP00000345785; ENSG00000188763; Homo sapiens. [Genome view]
Organism-specific databases
HGNC	HGNC:4047. FZD9.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	Q8TAN2.
Gene expression databases
ArrayExpress	Q8TAN2.
Bgee	Q8TAN2.
Family and domain databases
InterPro	IPR000539. Frizzled. IPR020067. Frizzled-like_dom. IPR000024. Frizzled_Cys-rich. IPR020068. Frizzled_dom_subgr. IPR015526. Frizzled_related. IPR017981. GPCR_2-like. [Graphical view]
Gene3D	G3DSA:1.10.2000.10. Frizzled_Cys-rich. 1 hit.
PANTHER	PTHR11309. Fz_related. 1 hit.
Pfam	PF01534. Frizzled. 1 hit. PF01392. Fz. 1 hit. [Graphical view]
PRINTS	PR00489. FRIZZLED.
SMART	SM00063. FRI. 1 hit. [Graphical view]
PROSITE	PS50038. FZ. 1 hit. PS50261. G_PROTEIN_RECEP_F2_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8TAN2_HUMAN

Accession

Primary (citable) accession number: Q8TAN2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 19, 2010
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.