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Protein

TYMS opposite strand protein

Gene

TYMSOS

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000176912-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
TYMS opposite strand protein
Gene namesi
Name:TYMSOS
Synonyms:C18orf56
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:29553. TYMSOS.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134956204.

Polymorphism and mutation databases

BioMutaiC18orf56.
DMDMi294862427.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002867091 – 123TYMS opposite strand proteinAdd BLAST123

Proteomic databases

PaxDbiQ8TAI1.
PRIDEiQ8TAI1.

PTM databases

iPTMnetiQ8TAI1.
PhosphoSitePlusiQ8TAI1.

Expressioni

Gene expression databases

BgeeiENSG00000176912.
CleanExiHS_C18orf56.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CCNDBP1O952733EBI-742060,EBI-748961
FHL3Q136435EBI-742060,EBI-741101
KHDRBS2Q5VWX15EBI-742060,EBI-742808
KRTAP10-5P603703EBI-742060,EBI-10172150
KRTAP10-8P604105EBI-742060,EBI-10171774
KRTAP10-9P604113EBI-742060,EBI-10172052
MDFIQ997506EBI-742060,EBI-724076

Protein-protein interaction databases

BioGridi138970. 10 interactors.
IntActiQ8TAI1. 15 interactors.
MINTiMINT-1459427.

Structurei

3D structure databases

ProteinModelPortaliQ8TAI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410KC8G. Eukaryota.
ENOG4110P84. LUCA.
InParanoidiQ8TAI1.

Sequencei

Sequence statusi: Complete.

Q8TAI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPASGATAS LGRLRARPRS RWDAAYLPAV AAVCVARASH VPNGTLRFGV
60 70 80 90 100
CKARRTMRPL PRRIEVRTKR GPQRPAAPER SPQPRLPPSR HPSRRGPRRH
110 120
LSGCSAPACR IPTGCRCPCG RPS
Length:123
Mass (Da):13,402
Last modified:April 20, 2010 - v2
Checksum:i8897DD5FFF08A090
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03216262R → G.1 PublicationCorresponds to variant rs2853533dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289986 mRNA. Translation: BAF82675.1.
AP001178 Genomic DNA. No translation available.
BC028301 mRNA. Translation: AAH28301.1.
RefSeqiNP_001012734.2. NM_001012716.2.
UniGeneiHs.274959.

Genome annotation databases

GeneIDi494514.
KEGGihsa:494514.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289986 mRNA. Translation: BAF82675.1.
AP001178 Genomic DNA. No translation available.
BC028301 mRNA. Translation: AAH28301.1.
RefSeqiNP_001012734.2. NM_001012716.2.
UniGeneiHs.274959.

3D structure databases

ProteinModelPortaliQ8TAI1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi138970. 10 interactors.
IntActiQ8TAI1. 15 interactors.
MINTiMINT-1459427.

PTM databases

iPTMnetiQ8TAI1.
PhosphoSitePlusiQ8TAI1.

Polymorphism and mutation databases

BioMutaiC18orf56.
DMDMi294862427.

Proteomic databases

PaxDbiQ8TAI1.
PRIDEiQ8TAI1.

Protocols and materials databases

DNASUi494514.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi494514.
KEGGihsa:494514.

Organism-specific databases

CTDi494514.
GeneCardsiTYMSOS.
HGNCiHGNC:29553. TYMSOS.
neXtProtiNX_Q8TAI1.
PharmGKBiPA134956204.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410KC8G. Eukaryota.
ENOG4110P84. LUCA.
InParanoidiQ8TAI1.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000176912-MONOMER.

Miscellaneous databases

GenomeRNAii494514.

Gene expression databases

BgeeiENSG00000176912.
CleanExiHS_C18orf56.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiTYMOS_HUMAN
AccessioniPrimary (citable) accession number: Q8TAI1
Secondary accession number(s): A8K1S1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: April 20, 2010
Last modified: November 30, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Product of a dubious CDS prediction. Overlap the TYMS locus in the opposite strand.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 18
    Human chromosome 18: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.