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Q8TA83 (DNJ10_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DnaJ homolog dnj-10
Alternative name(s):
DnaJ domain protein 10
Gene names
Name:dnj-10
ORF Names:F22B7.5
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length456 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 1 CR-type zinc finger.

Contains 1 J domain.

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform a Ref.1 (identifier: Q8TA83-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Note: No experimental confirmation available.
Isoform b Ref.1 (identifier: Q8TA83-2)

The sequence of this isoform differs from the canonical sequence as follows:
     418-456: GASESQKRRSEPVAENAETIDENQENEGFFEKIKRKIFG → DKSEEKSESKEEPKNEESSETPEKKAAES
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 456456DnaJ homolog dnj-10
PRO_0000071136

Regions

Domain44 – 10865J
Repeat208 – 2158CXXCXGXG motif
Repeat231 – 2388CXXCXGXG motif
Repeat245 – 2528CXXCXGXG motif
Zinc finger178 – 25780CR-type
Compositional bias108 – 14740Gly-rich

Natural variations

Alternative sequence418 – 45639GASES…RKIFG → DKSEEKSESKEEPKNEESSE TPEKKAAES in isoform b. Ref.1
VSP_051736

Sequences

Sequence LengthMass (Da)Tools
Isoform a [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 94168108B65B73B4

FASTA45650,136
        10         20         30         40         50         60 
MFVLNRSSGL IHRSVPLLAQ VSTPTTSTTK LAQLHTTHAL SKEDYYKTLG VDKKSDAKAI 

        70         80         90        100        110        120 
KKAYFQLAKK YHPDVNKTKE AQTKFQEISE AYEVLSDDTK RQEYDAYGSG GGPAGGRGGA 

       130        140        150        160        170        180 
GGFHHHGNVD VNEIFRRAFG GGGGMGGFNF DNFAQSAFGH SAAQEMVMDI SFEEAVRGAT 

       190        200        210        220        230        240 
KNVSVNVVED CLKCHGTQVE PGHKKTSCPY CNGTGAVSQR LQGGFFYQTT CNRCRGSGHY 

       250        260        270        280        290        300 
NKNPCQECEG EGQTVQRRQV SFNVPAGTNN GDSLKFQVGK NQLFVRFNVA PSLKFRREKD 

       310        320        330        340        350        360 
DIHCDVDISL AQAVLGGTVK VPGINGDTYV HIPAGTGSHT KMRLTGKGVK RLHSYGNGDQ 

       370        380        390        400        410        420 
YMHIKVTVPK YLTAEQKQIM LAWAATEQLK DGTIKGLEKN QKTEEKETKK NEEKKSEGAS 

       430        440        450 
ESQKRRSEPV AENAETIDEN QENEGFFEKI KRKIFG

« Hide

Isoform b [UniParc].

Checksum: 18ED5D100D5EFD3E
Show »

FASTA44648,934

References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING.
Strain: Bristol N2.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FO080222 Genomic DNA. Translation: CCD62135.1.
FO080222 Genomic DNA. Translation: CCD62136.1.
RefSeqNP_498901.1. NM_066500.4.
NP_498902.1. NM_066501.3.

3D structure databases

ProteinModelPortalQ8TA83.
SMRQ8TA83. Positions 41-357.
ModBaseSearch...

Protein-protein interaction databases

DIPDIP-24664N.
IntActQ8TA83. 8 interactions.
MINTMINT-1038768.
STRING6239.F22B7.5a.1.

Proteomic databases

PaxDbQ8TA83.
PRIDEQ8TA83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaF22B7.5a.1; F22B7.5a.1; F22B7.5.
F22B7.5a.2; F22B7.5a.2; F22B7.5.
GeneID176211.
KEGGcel:CELE_F22B7.5.
UCSCF22B7.5a.1. c. elegans.

Organism-specific databases

CTD176211.
WormBaseF22B7.5a; CE24911; WBGene00001028; dnj-10.
F22B7.5b; CE27991; WBGene00001028; dnj-10.

Phylogenomic databases

eggNOGCOG0484.
GeneTreeENSGT00700000104316.
HOGENOMHOG000226717.
InParanoidQ8TA83.
KOK09504.
OMAPAGTGSH.

Family and domain databases

Gene3D1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
InterProIPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
IPR001878. Znf_CCHC.
[Graphical view]
PfamPF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
[Graphical view]
PRINTSPR00625. JDOMAIN.
SMARTSM00271. DnaJ. 1 hit.
SM00343. ZnF_C2HC. 2 hits.
[Graphical view]
SUPFAMSSF46565. DnaJ_N. 1 hit.
SSF49493. HSP40_DnaJ_pep. 1 hit.
SSF57938. HSP_DnaJ_cys-rich. 1 hit.
PROSITEPS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio891598.

Entry information

Entry nameDNJ10_CAEEL
AccessionPrimary (citable) accession number: Q8TA83
Secondary accession number(s): P34408, Q95QJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: June 1, 2002
Last modified: May 1, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase

SIMILARITY comments

Index of protein domains and families

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