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Q8T9Z7

- Q8T9Z7_PLAFA

UniProt

Q8T9Z7 - Q8T9Z7_PLAFA

Protein
Submitted name:

Purine nucleoside phosphorylase

Gene

PNP

Organism
Plasmodium falciparum
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. purine-nucleoside phosphorylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. nucleoside metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosyltransferaseImported, Transferase

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-16356.
    BRENDAi2.4.2.1. 1455.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Purine nucleoside phosphorylaseImported (EC:2.4.2.1Imported)
    Gene namesi
    Name:PNPImported
    OrganismiPlasmodium falciparumImported
    Taxonomic identifieri5833 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8T9Z7.

    Interactioni

    Structurei

    3D structure databases

    ProteinModelPortaliQ8T9Z7.
    SMRiQ8T9Z7. Positions 3-245.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG2820.

    Family and domain databases

    Gene3Di3.40.50.1580. 1 hit.
    InterProiIPR018017. Nucleoside_phosphorylase.
    IPR000845. Nucleoside_phosphorylase_d.
    [Graphical view]
    PANTHERiPTHR21234. PTHR21234. 1 hit.
    PfamiPF01048. PNP_UDP_1. 1 hit.
    [Graphical view]
    SUPFAMiSSF53167. SSF53167. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8T9Z7-1 [UniParc]FASTAAdd to Basket

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    MDNLLRHLKI SKEQITPVVL VVGDPGRVDK IKVVCDSYVD LAYNREYKSV    50
    ECHYKGQKFL CVSHGVGSAG CAVCFEELCQ NGAKVIIRAG SCGSLQPDLI 100
    KRGDICICNA AVREDRVSHL LIHGDFPAVG DFDVYDTLNK CAQELNVPVF 150
    NGISVSSDMY YPNKIIPSRL EDYSKANAAV VEMELATLMV IGTLRKVKTG 200
    GILIVDGCPF KWDEGDFDNN LVPHQLENMI KIALGACAKL ATKYA 245
    Length:245
    Mass (Da):26,858
    Last modified:June 1, 2002 - v1
    Checksum:i2159E9731C410A23
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF426159 Genomic DNA. Translation: AAL74412.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF426159 Genomic DNA. Translation: AAL74412.1 .

    3D structure databases

    ProteinModelPortali Q8T9Z7.
    SMRi Q8T9Z7. Positions 3-245.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi Q8T9Z7.
    ChEMBLi CHEMBL5648.

    Proteomic databases

    PRIDEi Q8T9Z7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    eggNOGi COG2820.

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-16356.
    BRENDAi 2.4.2.1. 1455.

    Family and domain databases

    Gene3Di 3.40.50.1580. 1 hit.
    InterProi IPR018017. Nucleoside_phosphorylase.
    IPR000845. Nucleoside_phosphorylase_d.
    [Graphical view ]
    PANTHERi PTHR21234. PTHR21234. 1 hit.
    Pfami PF01048. PNP_UDP_1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53167. SSF53167. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum."
      Kicska G.A., Tyler P.C., Evans G.B., Furneaux R.H., Kim K., Schramm V.L.
      J. Biol. Chem. 277:3219-3225(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8T9Z7_PLAFA
    AccessioniPrimary (citable) accession number: Q8T9Z7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)