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Q8T9Z7

- Q8T9Z7_PLAFA

UniProt

Q8T9Z7 - Q8T9Z7_PLAFA

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Protein
Submitted name:

Purine nucleoside phosphorylase

Gene
PNP
Organism
Plasmodium falciparum
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. purine-nucleoside phosphorylase activity Source: UniProtKB-EC

GO - Biological processi

  1. nucleoside metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-16356.
BRENDAi2.4.2.1. 1455.

Names & Taxonomyi

Protein namesi
Submitted name:
Purine nucleoside phosphorylaseImported (EC:2.4.2.1Imported)
Gene namesi
Name:PNPImported
OrganismiPlasmodium falciparumImported
Taxonomic identifieri5833 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Laverania)

PTM / Processingi

Proteomic databases

PRIDEiQ8T9Z7.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ8T9Z7.
SMRiQ8T9Z7. Positions 3-245.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2820.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
InterProiIPR018017. Nucleoside_phosphorylase.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8T9Z7-1 [UniParc]FASTAAdd to Basket

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MDNLLRHLKI SKEQITPVVL VVGDPGRVDK IKVVCDSYVD LAYNREYKSV    50
ECHYKGQKFL CVSHGVGSAG CAVCFEELCQ NGAKVIIRAG SCGSLQPDLI 100
KRGDICICNA AVREDRVSHL LIHGDFPAVG DFDVYDTLNK CAQELNVPVF 150
NGISVSSDMY YPNKIIPSRL EDYSKANAAV VEMELATLMV IGTLRKVKTG 200
GILIVDGCPF KWDEGDFDNN LVPHQLENMI KIALGACAKL ATKYA 245
Length:245
Mass (Da):26,858
Last modified:June 1, 2002 - v1
Checksum:i2159E9731C410A23
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF426159 Genomic DNA. Translation: AAL74412.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF426159 Genomic DNA. Translation: AAL74412.1 .

3D structure databases

ProteinModelPortali Q8T9Z7.
SMRi Q8T9Z7. Positions 3-245.
ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q8T9Z7.
ChEMBLi CHEMBL5648.

Proteomic databases

PRIDEi Q8T9Z7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

eggNOGi COG2820.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-16356.
BRENDAi 2.4.2.1. 1455.

Family and domain databases

Gene3Di 3.40.50.1580. 1 hit.
InterProi IPR018017. Nucleoside_phosphorylase.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view ]
PANTHERi PTHR21234. PTHR21234. 1 hit.
Pfami PF01048. PNP_UDP_1. 1 hit.
[Graphical view ]
SUPFAMi SSF53167. SSF53167. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum."
    Kicska G.A., Tyler P.C., Evans G.B., Furneaux R.H., Kim K., Schramm V.L.
    J. Biol. Chem. 277:3219-3225(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8T9Z7_PLAFA
AccessioniPrimary (citable) accession number: Q8T9Z7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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