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Protein

ABC transporter B family member 3

Gene

abcB3

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi549 – 556ATPPROSITE-ProRule annotation8
Nucleotide bindingi1227 – 1234ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

  • cAMP transport Source: dictyBase
  • sorocarp development Source: dictyBase

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-159418. Recycling of bile acids and salts.
R-DDI-193368. Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol.
R-DDI-382556. ABC-family proteins mediated transport.

Protein family/group databases

TCDBi3.A.1.201.23. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 3
Alternative name(s):
ABC transporter ABCB.3
Gene namesi
Name:abcB3
ORF Names:DDB_G0291714
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0291714. abcB3.

Subcellular locationi

Q8T9W4:
  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei185 – 205HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei232 – 252HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei303 – 323HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei325 – 345HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei410 – 430HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei457 – 477HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei838 – 858HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei882 – 902HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei968 – 988HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei989 – 1009HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1060 – 1080HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1134 – 1154HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003913241 – 1432ABC transporter B family member 3Add BLAST1432

Proteomic databases

PaxDbiQ8T9W4.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0201629.

Structurei

3D structure databases

ProteinModelPortaliQ8T9W4.
SMRiQ8T9W4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini180 – 479ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST300
Domaini514 – 750ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini837 – 1157ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST321
Domaini1192 – 1428ABC transporter 2PROSITE-ProRule annotationAdd BLAST237

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili117 – 163Sequence analysisAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi53 – 62Poly-Asn10
Compositional biasi76 – 101Poly-AsnAdd BLAST26
Compositional biasi808 – 812Poly-Lys5

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055. Eukaryota.
COG1132. LUCA.
InParanoidiQ8T9W4.
KOiK05658.
OMAiGSAKTME.
PhylomeDBiQ8T9W4.

Family and domain databases

Gene3Di1.20.1560.10. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 3 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8T9W4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDGNENNEN AQHDEYDEEE IEIPIDEIII EEVDDDHLLE GEGEFQIITQ
60 70 80 90 100
PSNNNNNSNN NNFGDIYVSN PNTPRNNNNN NNNNNNNNNN NNNNNNNNSN
110 120 130 140 150
NSFNNNKKNE VSIGISENTN ENNNKNNNNN NNNNDDYNDG ADERVKTEEE
160 170 180 190 200
IKKEAENELN QSVPFLSLFR FADNTDKVLM FLGTIAAVIN GAAMPTVSLV
210 220 230 240 250
FGLVVDAFKP TQFNDDPNYD IYDTVRSISF YLLMLGGGVF VLSYLETTLW
260 270 280 290 300
MIAGERQTSR IRREYLESTL RQEIGWFDTN KANELSSRIN SDTVLFEEAI
310 320 330 340 350
GEKVGRFIHF FSTFVAGFVI GFTKGWQLTL VITSVSPLLA IGGFFTAKMM
360 370 380 390 400
TQMTKLGQEA YSRAGGVAEE NIGSIRTVAT FSGEKLAIDK YSNNLKDART
410 420 430 440 450
VGYKRSFFNG LGLGFVQFVI LGTYALAFWY GSTLISNKVT NSVSDRPWTG
460 470 480 490 500
GDVVSVFFAV IIGATSIGQA SPCLALFAQG RGAAYKIFQV IDRQSKANPF
510 520 530 540 550
STRGIKPETL SGEIEFKDVG FHYPSRPDVP IFNGFNLKIK PGQTVGLVGD
560 570 580 590 600
SGGGKSTIIS LLERFYDPCQ GEILLDGEDI RKFNVRGLRQ KIGLVNQEPV
610 620 630 640 650
LFATTISENI RYGKEGATQD EIEEAAKLAN AHSFISQLPQ GYNTLVGEKG
660 670 680 690 700
VQMSGGQRQR IAIARAVIKN PNILLLDEST SALDAESTKL VQEALDVLMK
710 720 730 740 750
GRTTIVIAHN LSTIRNADVI IYIKKGVAVE RGTHDELMAK QGLYFDLVEK
760 770 780 790 800
QSHQQMYNLL ENGTRSRRSS TFSAEVNPLL DSFHVSKRSL RKNESESNKK
810 820 830 840 850
DKEDSNNKKK KKSNKKKVEE VPMSRVVKYN RPELGLWCFG FLSAVGTGAV
860 870 880 890 900
YPGFAMVFTE MLTIFQNPDP NYLTDHANFV ALMFVALAVG AGISNFFQGF
910 920 930 940 950
LFSVIGEKLT YRLRRDCFAA IMRQDVGWFD LPENSTGKLT SHLATDAALV
960 970 980 990 1000
QGMTSQRLGI VLQNILTMVG GLVIAFYSGW QLTLVIIACF PLVVITSKVQ
1010 1020 1030 1040 1050
MQILAGFSSK DGCGPAGQVA SEAISGIRTV ASFTTEKQVV ELYKKQQKGP
1060 1070 1080 1090 1100
SSEGIKKAHI SGFAFGFTQL ILFCVYCLSF WYGGKLVGSG VFGATDKEIS
1110 1120 1130 1140 1150
DNCTPQTIPY LWKDYDTCER AQNTIYGFNS MTRVFFAIVM SAIGVGQASS
1160 1170 1180 1190 1200
FAPDLAKAKA AAVSVFKLLD TPSKIDPTTE DGDRIDIVGG DIEFKNLHFS
1210 1220 1230 1240 1250
YPTRPDNSVF RGFTLTLQSG TTTALVGDSG GGKSTCLSLL QRFYNPVVGE
1260 1270 1280 1290 1300
IFIDGHNIKN LNVRHLRHLF GLVGQEPTLF SGTIADNIRY GKHDATQEEI
1310 1320 1330 1340 1350
EEASKLSNSH SFIIDLPNGY NTELGEKYTQ LSGGQKQRIA IARAIIRNPK
1360 1370 1380 1390 1400
ILLLDESTSA LDADSTKLVQ EALENVMKGR TTIVIAHNLL TIQNADCIAY
1410 1420 1430
VRAGQIIERG THDELLEAEG PYSQLWYNQQ QK
Length:1,432
Mass (Da):158,191
Last modified:June 1, 2002 - v1
Checksum:iDDBAF872C3DD5AF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF466306 Genomic DNA. Translation: AAL74250.1.
AAFI02000182 Genomic DNA. Translation: EAL61553.1.
RefSeqiXP_629966.1. XM_629964.1.

Genome annotation databases

EnsemblProtistsiEAL61553; EAL61553; DDB_G0291714.
GeneIDi8628296.
KEGGiddi:DDB_G0291714.

Similar proteinsi

Entry informationi

Entry nameiABCB3_DICDI
AccessioniPrimary (citable) accession number: Q8T9W4
Secondary accession number(s): Q54E96
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: June 1, 2002
Last modified: October 25, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families