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Protein

ABC transporter B family member 5

Gene

abcB5

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi493 – 500ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: dictyBase
  • ATP binding Source: UniProtKB-KW
  • transporter activity Source: dictyBase

GO - Biological processi

  • culmination involved in sorocarp development Source: dictyBase
  • transport Source: dictyBase

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-1369007. Mitochondrial ABC transporters.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 5
Alternative name(s):
ABC transporter ABCB.5
Gene namesi
Name:abcB5
ORF Names:DDB_G0292554
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 6, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0292554. abcB5.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei140 – 160HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei176 – 196HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei252 – 272HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei279 – 299HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei366 – 386HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei400 – 420HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

  • ATP-binding cassette (ABC) transporter complex Source: dictyBase
  • mitochondrion Source: dictyBase

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003913261 – 697ABC transporter B family member 5Add BLAST697

Proteomic databases

PaxDbiQ8T9W2.
PRIDEiQ8T9W2.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0201625.

Structurei

3D structure databases

ProteinModelPortaliQ8T9W2.
SMRiQ8T9W2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini140 – 426ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST287
Domaini460 – 695ABC transporterPROSITE-ProRule annotationAdd BLAST236

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi25 – 28Poly-Ser4
Compositional biasi41 – 44Poly-Asn4
Compositional biasi92 – 95Poly-Thr4

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0057. Eukaryota.
COG5265. LUCA.
InParanoidiQ8T9W2.
KOiK05662.
OMAiYEAQRYD.
PhylomeDBiQ8T9W2.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF90123. SSF90123. 1 hit.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 1 hit.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8T9W2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYSINRIGIH GISNKILSRP KFFHSSSSIF SLNQNLNNFK NNNNYILNGY
60 70 80 90 100
NKITHNHHHQ TLFHRHYSNL KQEQENKQQN VGKNSETSPS STTTTENITT
110 120 130 140 150
ATTATTKTDI KETQNSTMSM LKTVFKYLWP KDNNDSKIRI ITSVLLLLSA
160 170 180 190 200
KVLTVQIPFI FKDIVDSLTT TQSEMLTLPL GLLLAYGAVK ITSNGFQELR
210 220 230 240 250
QTIFSKVAHD AIRDVSCSTF KRLHQLDLTF HLSRQTGSLS RIIDRGGRGI
260 270 280 290 300
NFLLNSILFH VVPTAFEISL VSYVMYTTLG WEYSALSLAT IAAYTVFTVK
310 320 330 340 350
VTKWRTQFRV KMNKMDNEAS NKMMDSLINF ETVKYFNNDA LEVERYHNYL
360 370 380 390 400
KEYDKASLKT TSSLSFLNFG QALIFSLSMT AMMIMAAQGV VQGNLSVGDL
410 420 430 440 450
VLVNGLLFQI SLPLNFLGTV YREIKQSLVD MDHLFSLLNL NPKISDNKDS
460 470 480 490 500
KPLKLENGTI VFRDISFKYN DSVQVLNNVS FECEGGKRIA IVGSSGSGKS
510 520 530 540 550
TLLRLLYRFY DVSSGSIEID GQDIRGIQLE SLRKHIGVVP QDTVLFNDTI
560 570 580 590 600
YYNIAYGNPN ATKEQVENAA RAAHIHEVIL NMKNGYDTVV GERGLKLSGG
610 620 630 640 650
EKQRVSIARA ILKDSPIVFY DEATSSLDTE KEKLIMDALR ELFKGRTTIM
660 670 680 690
IAHRLSTIVD ADEIIVLGTG GIILERGNHQ QLLELEGKYR SMWLAQQ
Length:697
Mass (Da):78,531
Last modified:June 1, 2002 - v1
Checksum:i304CC7BC2F344F2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF466308 Genomic DNA. Translation: AAL74252.1.
AAFI02000194 Genomic DNA. Translation: EAL61080.1.
RefSeqiXP_629496.1. XM_629494.1.

Genome annotation databases

EnsemblProtistsiEAL61080; EAL61080; DDB_G0292554.
GeneIDi8628745.
KEGGiddi:DDB_G0292554.

Similar proteinsi

Entry informationi

Entry nameiABCB5_DICDI
AccessioniPrimary (citable) accession number: Q8T9W2
Secondary accession number(s): Q54D24
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 9, 2010
Last sequence update: June 1, 2002
Last modified: June 7, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families