ID   Q8T9N3_PLAFA            Unreviewed;       616 AA.
AC   Q8T9N3; Q8MM01;
DT   01-JUN-2002, integrated into UniProtKB/TrEMBL.
DT   01-JUN-2002, sequence version 1.
DT   24-JAN-2024, entry version 53.
DE   SubName: Full=BAEBL protein {ECO:0000313|EMBL:AAM45251.1};
DE   SubName: Full=Erythrocyte binding antigen region II {ECO:0000313|EMBL:CAD27555.1};
DE   SubName: Full=Erythrocyte binding protein-2 {ECO:0000313|EMBL:AAK55484.1};
DE   Flags: Fragment;
GN   Name=EBP2 {ECO:0000313|EMBL:AAK55484.1};
GN   Synonyms=eba-140 {ECO:0000313|EMBL:CAD27555.1};
OS   Plasmodium falciparum (malaria parasite P. falciparum).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5833 {ECO:0000313|EMBL:AAK55484.1};
RN   [1] {ECO:0000313|EMBL:AAK55484.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=3D7 {ECO:0000313|EMBL:AAK55484.1};
RX   PubMed=11814568; DOI=10.1016/S0166-6851(01)00428-5;
RA   Narum D.L., Fuhrmann S.R., Luu T., Sim B.K.;
RT   "A novel Plasmodium falciparum erythrocyte binding protein-2 (EBP2/BAEBL)
RT   involved in erythrocyte receptor binding.";
RL   Mol. Biochem. Parasitol. 119:159-168(2002).
RN   [2] {ECO:0000313|EMBL:AAM45251.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Mayer D.G., Mu J.-B., Feng X., Su X.-Z., Miller L.H.;
RT   "Polymorphisms in Plasmodium falciparum Erythrocyte-Binding Ligand Change
RT   its Receptor Specificity.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:CAD27555.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=12702678;
RA   Baum J., Thomas A.W., Conway D.J.;
RT   "Evidence for diversifying selection on erythrocyte-binding antigens of
RT   Plasmodium falciparum and P. vivax.";
RL   Genetics 163:1327-1336(2003).
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DR   EMBL; AH010777; AAK55484.1; -; Genomic_DNA.
DR   EMBL; AF507986; AAM45251.1; -; Genomic_DNA.
DR   EMBL; AF507987; AAM45252.1; -; Genomic_DNA.
DR   EMBL; AF507988; AAM45253.1; -; Genomic_DNA.
DR   EMBL; AJ438830; CAD27555.1; -; Genomic_DNA.
DR   EMBL; AJ438831; CAD27556.1; -; Genomic_DNA.
DR   EMBL; AJ438837; CAD27562.1; -; Genomic_DNA.
DR   EMBL; AJ438838; CAD27563.1; -; Genomic_DNA.
DR   EMBL; AJ438842; CAD27567.1; -; Genomic_DNA.
DR   EMBL; AJ438844; CAD27569.1; -; Genomic_DNA.
DR   EMBL; AJ438845; CAD27570.1; -; Genomic_DNA.
DR   EMBL; AJ438846; CAD27571.1; -; Genomic_DNA.
DR   EMBL; AJ438848; CAD27573.1; -; Genomic_DNA.
DR   EMBL; AJ438851; CAD27576.1; -; Genomic_DNA.
DR   EMBL; AJ438852; CAD27577.1; -; Genomic_DNA.
DR   EMBL; AJ438853; CAD27578.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8T9N3; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1301600; -.
DR   VEuPathDB; PlasmoDB:PfCD01_130006500; -.
DR   VEuPathDB; PlasmoDB:PfGB4_130007100; -.
DR   VEuPathDB; PlasmoDB:PfGN01_130007700; -.
DR   VEuPathDB; PlasmoDB:PfKE01_130006800; -.
DR   VEuPathDB; PlasmoDB:PfNF166_130006800; -.
DR   VEuPathDB; PlasmoDB:PfNF54_130006700; -.
DR   VEuPathDB; PlasmoDB:PfSN01_000019200; -.
DR   VEuPathDB; PlasmoDB:PfTG01_130006900; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro.
DR   Gene3D; 1.10.287.1660; -; 1.
DR   Gene3D; 1.20.58.830; -; 2.
DR   Gene3D; 1.20.1310.20; Duffy-antigen binding domain; 2.
DR   InterPro; IPR042202; Duffy-ag-bd_sf.
DR   InterPro; IPR008602; Duffy-antigen-binding.
DR   Pfam; PF05424; Duffy_binding; 2.
DR   SUPFAM; SSF140924; Duffy binding domain-like; 2.
PE   4: Predicted;
FT   DOMAIN          34..204
FT                   /note="Duffy-antigen binding"
FT                   /evidence="ECO:0000259|Pfam:PF05424"
FT   DOMAIN          338..508
FT                   /note="Duffy-antigen binding"
FT                   /evidence="ECO:0000259|Pfam:PF05424"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:AAK55484.1"
FT   NON_TER         616
FT                   /evidence="ECO:0000313|EMBL:AAK55484.1"
SQ   SEQUENCE   616 AA;  73498 MW;  D89A89BAB4ADF94C CRC64;
     QYTFIQKRTH LFACGIKRKS IKWICRENSE KITVCVPDRK IQLCIANFLN SRLETMEKFK
     EIFLISVNTE AKLLYNKNEG KDPSIFCNEL RNSFSDFRNS FIGDDMDFGG NTDRVKGYIN
     KKFSDYYKEK NVEKLNNIKK EWWEKNKANL WNHMIVNHKG NISKECAIIP AEEPQINLWI
     KEWNENFLME KKRLFLNIKD KCVENKKYEA CFGGCRLPCS SYTSFMKKSK TQMEVLTNLY
     KKKNSGVDKN NFLNDLFKKN NKNDLDDFFK NEKEYDDLCD CRYTATIIKS FLNGPAKNDV
     DIASQINVND LRGFGCNYKS NNEKSWNCTG TFTNKFPGTC EPPRRQTLCL GRTYLLHRGH
     EEDYKEHLLG ASIYEAQLLK YKYKEKDENA LCSIIQNSYA DLADIIKGSD IIKDYYGKKM
     EENLNKVNKD KKRNEESLKI FREKWWDENK ENVWKVMSAV LKNKETCKDY DKFQKIPQFL
     RWFKEWGDDF CEKRKEKIYS FESFKVECKK KDCDENTCKN KCSEYKKWID LKKSEYEKQV
     DKYTKDKNKK MYDNIDEVKN KEANVYLKEK SKECKDVNFD DKIFNESPNE YEDMCKKCDE
     IKYLNEIKYP KTKHDI
//