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Q8T8A7

- Q8T8A7_CIOIN

UniProt

Q8T8A7 - Q8T8A7_CIOIN

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Protein
Submitted name:

Glutamic acid decarboxylase

Gene

Ci-GAD

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Cofactori

Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. carboxy-lyase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. carboxylic acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Glutamic acid decarboxylaseImported
Gene namesi
Name:Ci-GADImported
OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
Taxonomic identifieri7719 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

Interactioni

Protein-protein interaction databases

STRINGi7719.ENSCINP00000004013.

Structurei

3D structure databases

ProteinModelPortaliQ8T8A7.
SMRiQ8T8A7. Positions 32-528.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000005382.
HOVERGENiHBG004980.
KOiK01580.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8T8A7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQKQSAWRFR SSSVGLIKVE PNNDDYSMNN GDFENSSSAD LLPFGKSDEK
60 70 80 90 100
TQLFLKEIFE ILLKYISKSF DRKCKILDFH HPHQLLEGIE GFSLNINGEA
110 120 130 140 150
ESLEQILVDC RDTLKYGVKT GHPRFFNQLS SGLDIVSLAA DWVTSTANTN
160 170 180 190 200
MFTFEIAPVF ILMEDVIIKR MMKIIGWENI DGIFSPGGSI NNLYSVMLAR
210 220 230 240 250
HKIMPDVKHS GLRGFPQLVM FQSKHAHYSN KRPAAILGIG LNNCIDIEVD
260 270 280 290 300
ERGHMKPEDL ELKILQSKLD GKVPFYVTAT AGTTVRGAFD EIVKISEVCK
310 320 330 340 350
KYKIWLHVDA AWGGAVMMSQ KHRHLVAGIE MSDSVTWNPH KMVGVVLQCS
360 370 380 390 400
MLLTKHKRLL ESCNNMRADY LFQQDKHYDI TYDTGDKTIQ CGRHVDVFKL
410 420 430 440 450
WLSWRAKGDK GFCHHVERCI ELARYLVRKI KKTPGFQLVF QEPEYSNVCF
460 470 480 490 500
WYYPPSIRNI CDEVIKNEKL GKVAPIIKSR MMERGSIMIG YQPLGSKVNF
510 520 530
FRCVISNCAV NYDDIDFMVG QIERLGHDID M
Length:531
Mass (Da):60,719
Last modified:June 1, 2002 - v1
Checksum:iAFD16187EDFACC6B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB072597 mRNA. Translation: BAB88854.1.
RefSeqiNP_001027785.1. NM_001032613.1.
UniGeneiCin.34157.

Genome annotation databases

GeneIDi448951.
KEGGicin:448951.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB072597 mRNA. Translation: BAB88854.1 .
RefSeqi NP_001027785.1. NM_001032613.1.
UniGenei Cin.34157.

3D structure databases

ProteinModelPortali Q8T8A7.
SMRi Q8T8A7. Positions 32-528.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7719.ENSCINP00000004013.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 448951.
KEGGi cin:448951.

Organism-specific databases

CTDi 445791.

Phylogenomic databases

eggNOGi COG0076.
HOGENOMi HOG000005382.
HOVERGENi HBG004980.
KOi K01580.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProi IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view ]
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Neural map of the larval central nervous system in the ascidian Ciona intestinalis."
    Takamura K., Minamida N., Okabe S.
    Zool. Sci. 27:191-203(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8T8A7_CIOIN
AccessioniPrimary (citable) accession number: Q8T8A7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)