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Q8T8A7

- Q8T8A7_CIOIN

UniProt

Q8T8A7 - Q8T8A7_CIOIN

Protein
Submitted name:

Glutamic acid decarboxylase

Gene

Ci-GAD

Organism
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. carboxy-lyase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. carboxylic acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glutamic acid decarboxylaseImported
    Gene namesi
    Name:Ci-GADImported
    OrganismiCiona intestinalis (Transparent sea squirt) (Ascidia intestinalis)Imported
    Taxonomic identifieri7719 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaEnterogonaPhlebobranchiaCionidaeCiona

    Interactioni

    Protein-protein interaction databases

    STRINGi7719.ENSCINP00000004013.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8T8A7.
    SMRiQ8T8A7. Positions 32-528.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000005382.
    HOVERGENiHBG004980.
    InParanoidiQ8T8A7.
    KOiK01580.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8T8A7-1 [UniParc]FASTAAdd to Basket

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    MQKQSAWRFR SSSVGLIKVE PNNDDYSMNN GDFENSSSAD LLPFGKSDEK    50
    TQLFLKEIFE ILLKYISKSF DRKCKILDFH HPHQLLEGIE GFSLNINGEA 100
    ESLEQILVDC RDTLKYGVKT GHPRFFNQLS SGLDIVSLAA DWVTSTANTN 150
    MFTFEIAPVF ILMEDVIIKR MMKIIGWENI DGIFSPGGSI NNLYSVMLAR 200
    HKIMPDVKHS GLRGFPQLVM FQSKHAHYSN KRPAAILGIG LNNCIDIEVD 250
    ERGHMKPEDL ELKILQSKLD GKVPFYVTAT AGTTVRGAFD EIVKISEVCK 300
    KYKIWLHVDA AWGGAVMMSQ KHRHLVAGIE MSDSVTWNPH KMVGVVLQCS 350
    MLLTKHKRLL ESCNNMRADY LFQQDKHYDI TYDTGDKTIQ CGRHVDVFKL 400
    WLSWRAKGDK GFCHHVERCI ELARYLVRKI KKTPGFQLVF QEPEYSNVCF 450
    WYYPPSIRNI CDEVIKNEKL GKVAPIIKSR MMERGSIMIG YQPLGSKVNF 500
    FRCVISNCAV NYDDIDFMVG QIERLGHDID M 531
    Length:531
    Mass (Da):60,719
    Last modified:June 1, 2002 - v1
    Checksum:iAFD16187EDFACC6B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB072597 mRNA. Translation: BAB88854.1.
    RefSeqiNP_001027785.1. NM_001032613.1.
    UniGeneiCin.34157.

    Genome annotation databases

    GeneIDi448951.
    KEGGicin:448951.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB072597 mRNA. Translation: BAB88854.1 .
    RefSeqi NP_001027785.1. NM_001032613.1.
    UniGenei Cin.34157.

    3D structure databases

    ProteinModelPortali Q8T8A7.
    SMRi Q8T8A7. Positions 32-528.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7719.ENSCINP00000004013.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 448951.
    KEGGi cin:448951.

    Organism-specific databases

    CTDi 445791.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000005382.
    HOVERGENi HBG004980.
    InParanoidi Q8T8A7.
    KOi K01580.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Neural map of the larval central nervous system in the ascidian Ciona intestinalis."
      Takamura K., Minamida N., Okabe S.
      Zool. Sci. 27:191-203(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ8T8A7_CIOIN
    AccessioniPrimary (citable) accession number: Q8T8A7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)