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Reviewed, UniProtKB/Swiss-Prot Q8T6J1 (ABCA6_DICDI)

Last modified December 15, 2009. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    ABC transporter A family member 6
Alternative name(s):
    ABC transporter ABCA.6
Gene names
Name: abcA6
ORF Names: DDB_G0291245
OrganismDictyostelium discoideum (Slime mold) [Complete proteome]
Taxonomic identifier44689 [NCBI]
Taxonomic lineageEukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

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Protein attributes

Sequence length1631 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCA family.

Contains 2 ABC transporter domains.

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Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainRepeat
Transmembrane
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtransport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

ATPase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 16311631ABC transporter A family member 6
PRO_0000363838

Regions

Transmembrane25 – 4521 Potential
Transmembrane242 – 26221 Potential
Transmembrane285 – 30521 Potential
Transmembrane317 – 33721 Potential
Transmembrane346 – 36621 Potential
Transmembrane372 – 39221 Potential
Transmembrane416 – 43621 Potential
Transmembrane866 – 88621 Potential
Transmembrane1047 – 106721 Potential
Transmembrane1099 – 111921 Potential
Transmembrane1127 – 114721 Potential
Transmembrane1158 – 117821 Potential
Transmembrane1198 – 121821 Potential
Transmembrane1242 – 126221 Potential
Domain491 – 724234ABC transporter 1
Domain1309 – 1544236ABC transporter 2
Nucleotide binding527 – 5348ATP 1 Potential
Nucleotide binding1347 – 13548ATP 2 Potential
Compositional bias141 – 1455Poly-Gly
Compositional bias330 – 3334Poly-Leu

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Sequences

Sequence LengthMass (Da)Tools
Q8T6J1-1 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 54139209CFF6EA4D

FASTA1,631181,971
        10         20         30         40         50         60 
MEFGRQLKTL LKKNLLLKGK SKCSICCEIV FPIVIIGVLF AILALIKVTN SDYNSIDVTT 

        70         80         90        100        110        120 
FSRRVGPENK LLYGSEGSLN NDQSGVIETM KEQVATARGL TVAEVQDFFM EINDRTLMES 

       130        140        150        160        170        180 
FFKNYSMMVY GGVWFNSSTN GGGGGNNNDP IAAGGQFGYN IRLDSDDTAD TSETGKVDGG 

       190        200        210        220        230        240 
DSSIYLNDNF ASIQVAMDQA IFGYFGLDMV LNISGRHYPD PYTELWQEWI TGRDAIIKSA 

       250        260        270        280        290        300 
GSVFITAALM MFSFRLVTDV VIEKETKIVE AMRMMSLNSL AYFSSWIITS LITSLPVTLL 

       310        320        330        340        350        360 
IVVIFKGSQL IYSTSWGIVI ITFVLYLITL LLLSFIFSIF FNNSKFCGLL SFVIVIAINI 

       370        380        390        400        410        420 
CGIFVSKNEF SVSVKLLLSI FSPIAFSNSI YIMSVKDLTM ILNLNWDYIV TENQSILMLG 

       430        440        450        460        470        480 
IDIIIYIILI WYFEKVIPGE YGTKEKFYFL FTKNYWFGKK RSIGEIDDIE STFDSEDVET 

       490        500        510        520        530        540 
IPLKVLKNST ISIRNLRKEF ETGDGLRVAV NDLYLDMFED QIHALLGPNG CGKSTTIGML 

       550        560        570        580        590        600 
TGLISPTSGS AFIRGYDITS QMSKIRPYIG CCLQTDIIWS QLTVLEHLVI YASLKGVEGR 

       610        620        630        640        650        660 
NIQREAERMA TEVGLAEKMN APAGSLSGGQ KRKLCLGIAF IGRSKIIFLD EVTSGMDPVS 

       670        680        690        700        710        720 
RRQVWDFLLK YKKGKTIILT THYLEEADYL GDRIAIISQG KLRCDGTSLF LKNRFGQGYL 

       730        740        750        760        770        780 
LTCNKKLENA SNGFNTNQVS EFIKNFIPGA SILTDSGAEL SYRLPTESLS NFPQFFTEFD 

       790        800        810        820        830        840 
LNLSKFSIQT YGISVTSLEE VFISLGQEDS KKLNNNANGN NEFNKQNEME SLKLAIATPS 

       850        860        870        880        890        900 
DGINQIQQFK GLLIKRIQQS KKDARSFFLS IILPMALIIG SIILYKSMND QKQVLFYNNS 

       910        920        930        940        950        960 
TQPLTMSLSI YTDSDNTINV PMQLLNNELE WSNLFNNSPY FNKFKYINES INFNDYLIDN 

       970        980        990       1000       1010       1020 
YKLSIGAINF TNQPISIDDN NNGQSTNCSY IAYYNSDYIH SFPIHVNLIN DALLRKFKNI 

      1030       1040       1050       1060       1070       1080 
SISVTSMPFD HILTAFEISS SDINASAIIY FVFILMAGFS LMAGSFAGSI AQERTNRVKR 

      1090       1100       1110       1120       1130       1140 
LLYVSGCKKH IYWLSNLVWD FFFAFIISIL SCSILAGVIK GAFKEQFGSF LLCLILLSCA 

      1150       1160       1170       1180       1190       1200 
IIPLGYLMSY KFQTYGKAVG AITAILFVFG LVFTIASLNV RIQAVVNQNS TTQKVADIID 

      1210       1220       1230       1240       1250       1260 
LIFSIISPIF ALNRIVFILS GFPGSTRLGT FKVDNYWSFD YLGTPLIVLA GHAVLWNVWI 

      1270       1280       1290       1300       1310       1320 
LLLDYVPQIK GFFKNPKNLP APSPPQDEDY DVSQERRRLL NMRPSEEPIQ FKNLHKLFPG 

      1330       1340       1350       1360       1370       1380 
SGKNPSKTAV YNSTLGIPRG QTFGLLGLNG GGKSTTLSML SGEIVPSSGE ISINGYDVIT 

      1390       1400       1410       1420       1430       1440 
NREKALGNIS MVFQFDALIS LLSAREHLWL FSRIKGIKES QIENCVEAFI KMVDLTRIAN 

      1450       1460       1470       1480       1490       1500 
SGCGGYSGGN KRKVSLSMAM LGNPSVCFLD EISCGCDAVV RRQLWDVISE LGKDKSIILT 

      1510       1520       1530       1540       1550       1560 
SHSMSEVEAL CSRITIMKEG KYTCLNTIQG VKNRFGAGYS IDVKFKKEYL ETGIQTILQS 

      1570       1580       1590       1600       1610       1620 
IPNCTVLDQH DVMASFEVPN PPGNPIKLSN IFSILSNLPI LDDYNVGQTS LESVFLKLTG 

      1630 
ANHDQRINLY D

« Hide

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References

« Hide 'large scale' references
[1]"Evolutionary analyses of ABC transporters of Dictyostelium discoideum."
Anjard C., Loomis W.F.
Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE.
Strain: AX4.
[2]"The genome of the social amoeba Dictyostelium discoideum."
Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. expand/collapse author list , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.
Nature 435:43-57(2005) [PubMed: 15875012] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AX4.

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Cross-references

Sequence databases

AF465308 Genomic DNA. Translation: AAL85299.1.
AAFI02000177 Genomic DNA. Translation: EAL61606.1.
RefSeqXP_635211.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3386894.
GenomeReviewsGene locus abcA6 in contig CM000155_GR.
KEGGddi:DDB_0201627.

Organism-specific databases

dictyBaseDDB_G0291245. abcA6.

Phylogenomic databases

HOGENOMHBG082294.
InParanoidQ8T6J1.
OMAVIAINIC.

Family and domain databases

InterProIPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR003593. ATPase_AAA+_core.
[Graphical view]
PfamPF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
PROSITEPS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameABCA6_DICDI
AccessionPrimary (citable) accession number: Q8T6J1
Secondary accession number(s): Q54EM9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: June 1, 2002
Last modified: December 15, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

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Relevant documents

Dictyostelium discoideum

Dictyostelium discoideum: entries, gene names and cross-references to dictyBase

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents