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Protein

ABC transporter C family member 6

Gene

abcC6

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi510 – 517ATPPROSITE-ProRule annotation8
Nucleotide bindingi1135 – 1142ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: dictyBase
  • ATP binding Source: UniProtKB-KW
  • transporter activity Source: dictyBase

GO - Biological processi

  • culmination involved in sorocarp development Source: dictyBase
  • sorocarp morphogenesis Source: GO_Central
  • transmembrane transport Source: GO_Central
  • transport Source: dictyBase

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DDI-382556. ABC-family proteins mediated transport.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter C family member 6
Alternative name(s):
ABC transporter ABCC.6
Gene namesi
Name:abcC6
ORF Names:DDB_G0287593
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyosteliidaDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 5, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0287593. abcC6.

Subcellular locationi

Q8T6H3:
  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei120 – 140HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei149 – 169HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei248 – 268HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei771 – 791HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei815 – 835HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei904 – 924HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei977 – 999HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei1002 – 1022HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei1025 – 1045HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003638511 – 1351ABC transporter C family member 6Add BLAST1351

Proteomic databases

PaxDbiQ8T6H3.
PRIDEiQ8T6H3.

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0219975.

Structurei

3D structure databases

ProteinModelPortaliQ8T6H3.
SMRiQ8T6H3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 397ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST286
Domaini474 – 700ABC transporter 1PROSITE-ProRule annotationAdd BLAST227
Domaini777 – 1060ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST284
Domaini1101 – 1336ABC transporter 2PROSITE-ProRule annotationAdd BLAST236

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili701 – 734Sequence analysisAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi470 – 473Poly-Glu4

Sequence similaritiesi

Keywords - Domaini

Coiled coil, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0054. Eukaryota.
COG1132. LUCA.
InParanoidiQ8T6H3.
OMAiMEYIGAC.
PhylomeDBiQ8T6H3.

Family and domain databases

Gene3Di1.20.1560.10. 2 hits.
InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR036640. ABC1_TM_sf.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
SMARTiView protein in SMART
SM00382. AAA. 2 hits.
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiView protein in PROSITE
PS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 2 hits.
PS50893. ABC_TRANSPORTER_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8T6H3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFTKILKKFF SSYEKLKDNE DENEPSSNST NNFYKTCPED NSSKWSKISF
60 70 80 90 100
NWVTKLIMKG YLKESLEMND IYDLPELNKV QTTSKLLEDI DLSNNSNYTL
110 120 130 140 150
IKHIYKKFLP KNKYALVSNL FIIIFTFLSP ICLKFLINYI SIQDENEKSI
160 170 180 190 200
LKGILLCCLL CLCVLGQSIS QELFYWFGIK NGFDVRGALA AKIFEKTLKL
210 220 230 240 250
SNASRKEYKS GKIMNIMSID VANISEYFWT HHINIVSHFI QILSLVGLLC
260 270 280 290 300
YVVGPSGLVG FGVMVIALPI NAMLCAKSSN YLEKSLEYSD SRTNLTSELI
310 320 330 340 350
TNIRPFKMYA WENFFINKID GQRKQELKNI FLRIFYSILD HMMIETNATL
360 370 380 390 400
VLVSTFATYS LNGNTMSLDV TFTAMTIFSK LEVPLIRLPY DIFKAIGLIP
410 420 430 440 450
SVKRVQNFLK SSESLKYNKN FKNENQKITT TKENNNQHGQ DNDIIVENCT
460 470 480 490 500
FQWNEPENNN IFELNYGDNE EEENQDESIN KKENDNEEFN YKLKDINLIV
510 520 530 540 550
PKGKLTMICG VVGSGKTSLI FGLIGEIYKL NGSVSGVPNN ISFTSQQPFL
560 570 580 590 600
LSASLRENIL FGNEFDIERY KKVIESTALT KDIVNLAGLD LTEIGERGIN
610 620 630 640 650
LSGGQKQRIS LARALYANSD CFIFDEPLSA VDPEVASHLF DHCIQGELMR
660 670 680 690 700
NKTRILVTHQ LQFIPYADHI IVLNSNGQLI QGTYQELNEK GIDFKSILKT
710 720 730 740 750
KEIKKNVENE TDSEELIKNE IEIENEIIDV NNAISDKNDP NLIEKAKLLV
760 770 780 790 800
KEDKNEGEVE FNVYKKYFSY GSSGVTLFIT ISLFFVGQAI FKVSDFWLTI
810 820 830 840 850
WTERSIEGKS DSFYIGYYLL IFGTFVVILM IRILLLCRIT FNVGKNLHSA
860 870 880 890 900
LLKSVTYASC RFFDTNPSGR ILNRFSKDTS DIDIHMFDIL TEVSMCFSEL
910 920 930 940 950
TIGLISIVFI IPIMVIPLII LSIAYYILQR LYRPSARELN RWESITVSPI
960 970 980 990 1000
FSLLQECYNG LLTIRTYKQE SRFIKEMFDN ININLGCFFY SFAVHRWVSM
1010 1020 1030 1040 1050
RLEVMGWIMV FFTSLIATLF ISNNGLAALS VTTALSLNGY LSWGIRRIVD
1060 1070 1080 1090 1100
LEVKMNSFQR IQSYIEIPKE GNKLVSTNSN EVDNHTIKDA DLVNWPNKGI
1110 1120 1130 1140 1150
IEFKNVEIKY RPNSEPNLKD LSFKVQSSEK IGIVGRTGAG KTTIASSLFR
1160 1170 1180 1190 1200
MVECSKGLIL IDGIDISKVQ LQKLRSSIGI VPQDPFIFTG TIRSNIDPFN
1210 1220 1230 1240 1250
EFTDFEIWES VEKVKLKDAI NSMPLKLETA LQENGDNGFS YGQKQLLCLC
1260 1270 1280 1290 1300
RTILKNFKII LMDEATSSID YHTAQLIKQT IQENFKDCTT LTIAHRLETI
1310 1320 1330 1340 1350
IDCNKIAVID SGQLIEFDTP SNLMNIPNSK FNKLIKSQTD YNNNEKTIIN

K
Length:1,351
Mass (Da):154,308
Last modified:June 1, 2002 - v1
Checksum:iFB3E88A0D05BA25A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF474338 Genomic DNA. Translation: AAL85709.1.
AAFI02000103 Genomic DNA. Translation: EAL63605.1.
RefSeqiXP_637141.1. XM_632049.1.

Genome annotation databases

EnsemblProtistsiEAL63605; EAL63605; DDB_G0287593.
GeneIDi8626236.
KEGGiddi:DDB_G0287593.

Similar proteinsi

Entry informationi

Entry nameiABCC6_DICDI
AccessioniPrimary (citable) accession number: Q8T6H3
Secondary accession number(s): Q54K23
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: June 1, 2002
Last modified: October 25, 2017
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Dictyostelium discoideum
    Dictyostelium discoideum: entries, gene names and cross-references to dictyBase
  2. SIMILARITY comments
    Index of protein domains and families