Q8T6B7 (ABCF2_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ABC transporter F family member 2

Gene names

Name:	abcF2
ORF Names:	DDB_G0284047

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	593 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. Contains 2 ABC transporter domains.
Caution	Lacks transmembrane domains and is probably not involved in transport.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from sequence or structural similarity Ref.1. Source: dictyBase ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 593	593	ABC transporter F family member 2		PRO_0000365607
Regions
	Domain	53 – 294	242	ABC transporter 1
	Domain	364 – 583	220	ABC transporter 2
	Nucleotide binding	85 – 92	8	ATP 1 By similarity
	Nucleotide binding	399 – 406	8	ATP 2 By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8T6B7 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: E3C3C76A1CB1FB5E	FASTA	593	66,841
	10 20 30 40 50 60 MAKKGGKNNK SKKEVTPPTS DVEDEVQDKF KEMRLNAFTA TGALASKESS RDVKIEQVTL 70 80 90 100 110 120 TFHGKELLSD TTVEINFGRR YGLIGQNGCG KSTFFQCLAV RELPIPEHID IFHLSEEAHP 130 140 150 160 170 180 SERTALQSVI DDAEKEVKRL EVLEERLLEE QGPESEELFD VYERLENLDP TTFVPRASEI 190 200 210 220 230 240 LIGLGFTSQT MLKKTKDLSG GWRMRVSLAK ALFIKPTLLL LDEPTNHLDL GACVWLEDYL 250 260 270 280 290 300 ANYDRSLIII SHSQDFLNAV CTNIIHMTQS KLKYYGGNYD NFVKTKAELE VNQMKAYHKQ 310 320 330 340 350 360 QEEIAHIKSF IASCGTYSNL VRQGKSKQKI IDKMEEAGLV ERVQEDKIFN FSFPPCGELA 370 380 390 400 410 420 PPIMHFDNVT FSYSGKEADV LYRNLDLAID LDSRIALVGP NGAGKSTLLK LMVGQISPTQ 430 440 450 460 470 480 GFIKKHSHLK MARYHQHAHE VLDLTATPLD FVRSKFAHMN KDTEEWRREI GRFGVTGKAQ 490 500 510 520 530 540 TEAIGCMSDG IKSRLIFCLM ALENPHLLLL DEPTNHLDME CIDSLALAIN SFPGGMILVS 550 560 570 580 590 HDFRLISQVA KEIWVCDNKT ITKWAGDITS YKNHLKAQMR DLTKQGALAS LKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF479254 Genomic DNA. Translation: AAL87692.1. AAFI02000063 Genomic DNA. Translation: EAL65364.1.
RefSeq	XP_638739.1. XM_633647.1.
3D structure databases
ProteinModelPortal	Q8T6B7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8T6B7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0191228; DDB0191228; DDB_G0284047.
GeneID	8624409.
GenomeReviews	Gene locus abcF2 in contig CM000153_GR.
KEGG	ddi:DDB_G0284047.
Organism-specific databases
dictyBase	DDB_G0284047. abcF2.
Phylogenomic databases
eggNOG	KOG0927.
GeneTree	EPrGT00050000000412.
HOGENOM	HBG758042.
InParanoid	Q8T6B7.
OMA	HEENGDT.
PhylomeDB	Q8T6B7.
ProtClustDB	CLSZ2430299.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K06185.
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCF2_DICDI

Accession

Primary (citable) accession number: Q8T6B7
Secondary accession number(s): Q54Q58

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	June 1, 2002
Last modified:	November 16, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)