Reviewed, UniProtKB/Swiss-Prot Q8T6B4 (ABCF4_DICDI)

Names and origin

Protein names

Recommended name:
    ABC transporter F family member 4

Gene names

Name:	abcF4
ORF Names:	DDB_G0267436

Organism

Dictyostelium discoideum (Slime mold) [Complete proteome]

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	1142 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. Contains 2 ABC transporter domains.

Ontologies

Keywords
Biological process	Transport
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1142	1142	ABC transporter F family member 4		PRO_0000346859
Regions
	Domain	604 – 857	254	ABC transporter 1
	Domain	923 – 1139	217	ABC transporter 2
	Nucleotide binding	636 – 643	8	ATP Potential
	Nucleotide binding	956 – 963	8	ATP Potential
	Compositional bias	4 – 564	561	Lys-rich
	Compositional bias	76 – 172	97	Gln-rich
	Compositional bias	202 – 568	367	Glu-rich

Sequences

	Sequence		Length	Mass (Da)
	Q8T6B4-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 33B1815AB09942DC	FASTA	1,142	130,225
	10 20 30 40 50 60 MGPKGKKKGQ SFDDSDEEIN NKKGGNKKGQ QLEDDIPQPV KKGGNKKGQR GKQDSDDEPE 70 80 90 100 110 120 NIPQPVAKKS NNKKGQRGKQ DSDDEQDEIP QPQKKGGKPA PQPQKKGGKQ QDSDDEQDEI 130 140 150 160 170 180 PQPVKKGGKP APQKKGGKQQ QQQDSDDEQE EIPQPVKKGG KPAPQKKGGK QQDSDDEEDE 190 200 210 220 230 240 IPQPVKKGGK PAPQKKGGKQ QESEDEDEED EVQQPVKKGG KNDKKKGVKH VEEEEEEEEE 250 260 270 280 290 300 EEIEQPVKKG GKAPKPKKGG KGSKQESEDE EDDVQQPVKK GGKKDKKKGS KHVEEEEEEE 310 320 330 340 350 360 EEEEIEQPVK KGSNKKDQKK GGKGKHVEEE EEEEEEEEIE QPVKKGSNKK DQKKGGKGKQ 370 380 390 400 410 420 QQESEDEEEE IQQPVKKGGK KDKKKGSKHV EEEEEEEEEE EEIEQPVKKG GKKDKKSSLE 430 440 450 460 470 480 DSMSELSIKS KKGGKGKHVE EEEEQEQEEE EEKPKSKSNK KDKKKGKHVE EEEEEEEEEE 490 500 510 520 530 540 EKPKSKSNKK DKKKGSKHIE EEEEEEEEEE EEEKEEEEEK KMTLAEIRAA KKVKKVDKKE 550 560 570 580 590 600 KKKEKEKKKR DEQEEDAFEL AKKKQQEEID YDNIDIDDVP GKDAPTYVHL KSSEGLRSKI 610 620 630 640 650 660 GNDIKFDNLI LSVPGRILLN NASLTLAYGQ KYGFVGRNGI GKSTLVKKIA MRDEITIAPH 670 680 690 700 710 720 LRVLYVEQEV TGDDTTPLDC VLAADEERKW LLDEEKVLTE LEKVNPSWQF DPRQKRNYSL 730 740 750 760 770 780 RDIYDRLKEI DADKASIRAA NILIGLGFTF EEISVKKSRD YSGGWRMRIA LARALFCKPE 790 800 810 820 830 840 VLLLDEPSNH LDLHACVWLE KYLNQWDRTL LVVSHEASFL NEVVDNIIYI HDQKLDQYRG 850 860 870 880 890 900 NYDAFMKQKS VNLRSKEKEK DKQDRKLKKM NEFITKNKNN TQAKQAASRA KKMEKIETIE 910 920 930 940 950 960 LEREDASLVV DFPQPEHLTP PLLVFKDVCF GYEGRPTMFK KLDIGIDMDS KIALVGMNGV 970 980 990 1000 1010 1020 GKSTLMKLMN GDLHETTGYI ERSRKMRVAR FSQHFVDQLD TTMTPIEYFQ SKFNNPPVQQ 1030 1040 1050 1060 1070 1080 IRNHLGRFGI CNSLPLHKIT TLSGGQKSRV ILAELAWAEP HILLLDEPTN HLDIDAIEAL 1090 1100 1110 1120 1130 1140 AEGINAFTGG VVLISHNQHL INLIAEQIWV VKKDGTIYLY PGTFMDYKNE ISREIDNMVI RS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF479256 Genomic DNA. Translation: AAL87694.1. AAFI02000003 Genomic DNA. Translation: EAL73170.1.
RefSeq	XP_647476.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3398804.
GenomeReviews	Gene locus abcF4 in contig CM000150_GR.
KEGG	ddi:DDB_0191119.
Organism-specific databases
dictyBase	DDB_G0267436. abcF4.
Phylogenomic databases
HOGENOM	HBG758042.
OMA	GEEQTGQ.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00005. ABC_tran. 2 hits. [Graphical view]
SMART	SM00382. AAA. 2 hits. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 2 hits. PS50893. ABC_TRANSPORTER_2. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCF4_DICDI

Accession

Primary (citable) accession number: Q8T6B4
Secondary accession number(s): Q55FQ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	June 1, 2002
Last modified:	December 15, 2009
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)