Q8T674 (ABCGK_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ABC transporter G family member 20

Alternative name(s):
ABC transporter ABCG.20

Gene names

Name:	abcG20
ORF Names:	DDB_G0267430

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	730 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-2 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	ATP-binding cassette (ABC) transporter complex Inferred from sequence or structural similarity Ref.1. Source: dictyBase integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from sequence or structural similarity Ref.1. Source: dictyBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 730	730	ABC transporter G family member 20		PRO_0000346860
Regions
	Transmembrane	520 – 540	21	Helical; Potential
	Transmembrane	572 – 592	21	Helical; Potential
	Transmembrane	602 – 622	21	Helical; Potential
	Transmembrane	634 – 654	21	Helical; Potential
	Transmembrane	692 – 712	21	Helical; Potential
	Domain	15 – 244	230	ABC transporter
	Domain	489 – 717	229	ABC transmembrane type-2
	Nucleotide binding	47 – 54	8	ATP Potential
	Compositional bias	3 – 10	8	Poly-Asn
	Compositional bias	262 – 332	71	Asn-rich

Sequences

	Sequence		Length	Mass (Da)
	Q8T674 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: F3E354832E2E75BA	FASTA	730	81,025
	10 20 30 40 50 60 MSNSNNNNNN KKLAISLKNV CRGYGNTKVI DNLNLQIKSG TINCLIGASG SGKTTILRTI 70 80 90 100 110 120 LGRLIPDSGE VLVFGKRPHD IGGVPGSICG FCPQEGALYY DLTLDHTLNF FSNVHQIPKD 130 140 150 160 170 180 KFESKKNEII KLLDLPQINS RSVGLLSGGQ KKRVSLAVAL LHSPKLLILD EPTVGIDMEV 190 200 210 220 230 240 ASNIWSYLRS LANSGVTIII TTHYINEAVG SDNVFLLRDG KILENGAPNY LIERYESQTL 250 260 270 280 290 300 EEVFLKLCKR DNAQSIVDSK KNNNNSYFSS QEIIDVESHI VNNNNNNNNN NNNNNYNNND 310 320 330 340 350 360 DEENYNDDIY NDKKPLIGIS KEDENNTNGS TNKESGILFR FYKVLLHSVA IGKRKFIQII 370 380 390 400 410 420 RNKVVLSFEL LSPSVQVLLY FLAIGGSPKN LEFGVVNLDV GPIGSMYINS LSNTGIFNFH 430 440 450 460 470 480 NYNSTTEAIE QIKSGNSFGL LDINAQFSEA ILENFMNLSQ YNPNGQIDLY MDFTNYQITL 490 500 510 520 530 540 IVEQQLALSF ETLAKQQANI TMNPIKTVTP TVYGNPNSKF IDFLAPGMVC LISFAHAISI 550 560 570 580 590 600 TSVSFVKEKV DGSLDRLFAY GVRTSSIVFG HFLGHLPLLL VQITVLLLIA IYGFNVPIEG 610 620 630 640 650 660 NIALVFLMTV SLAFVGMSLG LVISAVSRVE TEAIQLSLGV YFPTLICSGT LWPLQSLPNW 670 680 690 700 710 720 FVWFPNILPA THAGNAMRDI MLKGVGLHYK EVWVAFLVVL SWLIFLIFIA VLALNEKDKN 730 LKLSCFKKRK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF482397 Genomic DNA. Translation: AAL91504.1. AAFI02000003 Genomic DNA. Translation: EAL73167.1.
RefSeq	XP_647230.1. XM_642138.1.
3D structure databases
ProteinModelPortal	Q8T674.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0191238; DDB0191238; DDB_G0267430.
GeneID	8616035.
GenomeReviews	Gene locus abcG20 in contig CM000150_GR.
KEGG	ddi:DDB_G0267430.
Organism-specific databases
dictyBase	DDB_G0267430. abcG20.
Phylogenomic databases
eggNOG	KOG0059.
GeneTree	EPrGT00050000002981.
HOGENOM	HBG076084.
OMA	RHRTALY.
PhylomeDB	Q8T674.
ProtClustDB	CLSZ2431495.
Family and domain databases
InterPro	IPR000412. ABC_2. IPR013526. ABC_2_tran. IPR013525. ABC_2_trans. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF01061. ABC2_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
PRINTS	PR00164. ABC2TRNSPORT.
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS51012. ABC_TM2. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCGK_DICDI

Accession

Primary (citable) accession number: Q8T674
Secondary accession number(s): Q55GF4

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	June 1, 2002
Last modified:	September 21, 2011
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)