Q8T664 (ABCH2_DICDI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ABC transporter H family member 2

Gene names

Name:	abcH2
ORF Names:	DDB_G0267428

Organism

Dictyostelium discoideum (Slime mold)

Taxonomic identifier

44689 [NCBI]

Taxonomic lineage

Eukaryota › Amoebozoa › Mycetozoa › Dictyosteliida › Dictyostelium

Protein attributes

Sequence length	513 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the ABC transporter superfamily. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from sequence or structural similarity Ref.1. Source: dictyBase ATPase activity, coupled to transmembrane movement of substances Inferred from sequence or structural similarity Ref.1. Source: dictyBase
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 513	513	ABC transporter H family member 2		PRO_0000346861
Regions
	Domain	39 – 280	242	ABC transporter
	Nucleotide binding	75 – 82	8	ATP Potential
	Compositional bias	326 – 348	23	Poly-Asn
	Compositional bias	387 – 444	58	Poly-Asn
	Compositional bias	448 – 454	7	Poly-Asn
	Compositional bias	467 – 471	5	Poly-Asn

Sequences

	Sequence		Length	Mass (Da)
	Q8T664 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 16352F6711CBE581	FASTA	513	57,536
	10 20 30 40 50 60 MAQVFPDVIE EKIQDDDKFF GQTRLKNDDI DFNDPDNVLT MKNIHKTYLL GIEGVPALRG 70 80 90 100 110 120 VSMAIKRGEF ICIFGTSGGG KTTMLNIIGT IDKPTKGEMK LCGKTINHKT TDKDLAFLRL 130 140 150 160 170 180 RNIGFVFQTF NLLSSLTALE NVEMPMILLG ELSASERRER AISLLTKVGM KDRLDHFPSQ 190 200 210 220 230 240 LSGGEQQRVT IARAIANNPD VLLLDEPTGD LDTVNTSVIM KLLTDLNKQE NITLIMVTHD 250 260 270 280 290 300 VGLKMYSDRI IWMRDGKIQR IETVQEQSKR EHYQKLYKEC ELINQNQKNG VTSVFKNDDD 310 320 330 340 350 360 NKNIKKQGTL TEFRRPTDYK SIASYNNNNS NLNNNSNSNS NNNSNNNNSK NYASSSSSSS 370 380 390 400 410 420 VLNGKLSQST VNNSSIYNHN NDSPFFNSNN NNNINNNINN NNNNNNNNNN NNNNNNNNNN 430 440 450 460 470 480 NNNNNNNNSN SNNNNSNSNN NNNNTKSNNN NNNNIFDIAS SSSSYSNNNN NSKNNSLIDD 490 500 510 IYLDINEGSS SNFSNNDNFK SVDQITNDLS RIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evolutionary analyses of ABC transporters of Dictyostelium discoideum." Anjard C., Loomis W.F. Eukaryot. Cell 1:643-652(2002) [PubMed: 12456012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE. Strain: AX4.
[2]	"The genome of the social amoeba Dictyostelium discoideum." Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T., Lehmann R., Hamlin N. , Davies R., Gaudet P., Fey P., Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A. Nature 435:43-57(2005) [PubMed: 15875012] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AX4.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF482961 Genomic DNA. Translation: AAL96259.1. AAFI02000003 Genomic DNA. Translation: EAL73166.1.
RefSeq	XP_647545.1. XM_642453.1.
3D structure databases
HSSP	HSSP built from PDB template 1L2T based on UniProtKB Q58206.
ProteinModelPortal	Q8T664.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	DDB0191241; DDB0191241; DDB_G0267428.
GeneID	8616352.
GenomeReviews	Gene locus abcH2 in contig CM000150_GR.
KEGG	ddi:DDB_G0267428.
Organism-specific databases
dictyBase	DDB_G0267428. abcH2.
Phylogenomic databases
eggNOG	KOG0055.
GeneTree	EPrGT00050000001629.
HOGENOM	HBG758042.
OMA	ETNESHE.
PhylomeDB	Q8T664.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K02003.
Pfam	PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCH2_DICDI

Accession

Primary (citable) accession number: Q8T664
Secondary accession number(s): Q55FI8

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 2, 2008
Last sequence update:	June 1, 2002
Last modified:	November 16, 2011
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)