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Protein
Submitted name:

AT07738p

Gene

Rrp45

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DME-429958 mRNA decay by 3' to 5' exoribonuclease
R-DME-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-DME-6791226 Major pathway of rRNA processing in the nucleolus and cytosol

Names & Taxonomyi

Protein namesi
Submitted name:
AT07738pImported
Submitted name:
Rrp45, isoform AImported
Submitted name:
Rrp45, isoform BImported
Gene namesi
Name:Rrp45Imported
Synonyms:Dmel\CG9606Imported, dRrp45Imported, rrp45Imported
ORF Names:CG9606Imported, Dmel_CG9606Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome X

Organism-specific databases

FlyBaseiFBgn0030789 Rrp45

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PRIDEiQ8T4A9

Expressioni

Gene expression databases

BgeeiFBgn0030789

Interactioni

Protein-protein interaction databases

IntActiQ8T4A9, 1 interactor
STRINGi7227.FBpp0074129

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 169RNase_PHInterPro annotationAdd BLAST133

Phylogenomic databases

eggNOGiKOG1614 Eukaryota
COG2123 LUCA
GeneTreeiENSGT00530000063093
KOiK03678
OMAiMFMNSNL
OrthoDBiEOG091G08FZ

Family and domain databases

CDDicd11368 RNase_PH_RRP45, 1 hit
Gene3Di3.30.230.70, 1 hit
InterProiView protein in InterPro
IPR001247 ExoRNase_PH_dom1
IPR036345 ExoRNase_PH_dom2_sf
IPR027408 PNPase/RNase_PH_dom_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR033100 Rrp45
PfamiView protein in Pfam
PF01138 RNase_PH, 1 hit
SUPFAMiSSF54211 SSF54211, 2 hits
SSF55666 SSF55666, 1 hit

Sequencei

Sequence statusi: Complete.

Q8T4A9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFHNSNFFEP GKSKPERSFV QLAVKQNQRL DGRRSNESRD VELTFGKDWG
60 70 80 90 100
SVAVSMGDTK VLAQVTCEMG PPALSRPNEG KIHLNVYLGG VAFLDEAHTT
110 120 130 140 150
HDQRSLKLNS LLERTFRSSR SIDLESLCVA VEKHVWCIRV NVNVLNHDGN
160 170 180 190 200
LYDASTIATL AALMHFRRPD VWYKDGELRI FKKKEREFIP LLFHHYPVSV
210 220 230 240 250
TYCVYKSSVQ PILDPTLLEE NAADSVIVLS FNSFQELCSL TAGGTAPTNA
260 270 280 290 300
RIIMQCARNA AVRCKSLLNF VRKALALDEE CRSQGDQSVD GLVALILNTE
310 320 330 340 350
HKLSYNKLMG RQKQEQQPPP SEKMQLDNNE SSETPVANEE PSKEESAGAP
360 370 380 390 400
MDTSDWLPHD EDSQELPMRS EASPSKAGLK GKQSRGKYKA NKKTPPRKQN
410
HSDSEEEAKR YI
Length:412
Mass (Da):46,303
Last modified:June 1, 2002 - v1
Checksum:iD86F992BC5E57C1F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE014298 Genomic DNA Translation: AAF48665.2
AY089277 mRNA Translation: AAL90015.1
AE014298 Genomic DNA Translation: AHN59823.1
RefSeqiNP_001285353.1, NM_001298424.1
NP_573163.1, NM_132935.3
UniGeneiDm.19725

Genome annotation databases

EnsemblMetazoaiFBtr0074355; FBpp0074129; FBgn0030789
FBtr0344090; FBpp0310515; FBgn0030789
GeneIDi32665
KEGGidme:Dmel_CG9606
UCSCiCG9606-RA d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ8T4A9_DROME
AccessioniPrimary (citable) accession number: Q8T4A9
Secondary accession number(s): Q9VXB2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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