Q8T4A9 (Q8T4A9_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AT07738p EMBL AAL90015.1

Submitted name:
Rrp45 EMBL AAF48665.2
EC=3.1.13.- EMBL AAF48665.2

Gene names

Name:	Rrp45 FlyBase FBgn0030789
ORF Names:	CG9606 FlyBase FBgn0030789 EMBL AAL90015.1, Dmel_CG9606 EMBL AAF48665.2

Organism

Drosophila melanogaster (Fruit fly) [Reference proteome] EMBL AAL90015.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Eremoneura › Cyclorrhapha › Schizophora › Acalyptratae › Ephydroidea › Drosophilidae › Drosophilinae › Drosophilini › Drosophilina › Drosophiliti › Drosophila › Sophophora › melanogaster group › melanogaster subgroup

Protein attributes

Sequence length	412 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Hydrolase EMBL AAF48665.2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	exosome (RNase complex) Inferred from sequence or structural similarity PubMed 12490954. Source: FlyBase
Molecular_function	hydrolase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8T4A9 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: D86F992BC5E57C1F	FASTA	412	46,303
	10 20 30 40 50 60 MFHNSNFFEP GKSKPERSFV QLAVKQNQRL DGRRSNESRD VELTFGKDWG SVAVSMGDTK 70 80 90 100 110 120 VLAQVTCEMG PPALSRPNEG KIHLNVYLGG VAFLDEAHTT HDQRSLKLNS LLERTFRSSR 130 140 150 160 170 180 SIDLESLCVA VEKHVWCIRV NVNVLNHDGN LYDASTIATL AALMHFRRPD VWYKDGELRI 190 200 210 220 230 240 FKKKEREFIP LLFHHYPVSV TYCVYKSSVQ PILDPTLLEE NAADSVIVLS FNSFQELCSL 250 260 270 280 290 300 TAGGTAPTNA RIIMQCARNA AVRCKSLLNF VRKALALDEE CRSQGDQSVD GLVALILNTE 310 320 330 340 350 360 HKLSYNKLMG RQKQEQQPPP SEKMQLDNNE SSETPVANEE PSKEESAGAP MDTSDWLPHD 370 380 390 400 410 EDSQELPMRS EASPSKAGLK GKQSRGKYKA NKKTPPRKQN HSDSEEEAKR YI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014298 Genomic DNA. Translation: AAF48665.2. AY089277 mRNA. Translation: AAL90015.1.
RefSeq	NP_573163.1. NM_132935.2.
UniGene	Dm.19725.
3D structure databases
SMR	Q8T4A9. Positions 13-284.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8T4A9. 1 interaction.
STRING	7227.FBpp0074129.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0074355; FBpp0074129; FBgn0030789.
GeneID	32665.
KEGG	dme:Dmel_CG9606.
UCSC	CG9606-RA. d. melanogaster.
Organism-specific databases
CTD	32665.
FlyBase	FBgn0030789. Rrp45.
Phylogenomic databases
eggNOG	COG2123.
GeneTree	ENSGT00530000063093.
InParanoid	Q8T4A9.
KO	K03678.
OMA	LESLCVA.
OrthoDB	EOG495X81.
Family and domain databases
InterPro	IPR001247. ExoRNase_PH_dom1. IPR020568. Ribosomal_S5_D2-typ_fold. [Graphical view]
Pfam	PF01138. RNase_PH. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	32665.
NextBio	779732.

Entry information

Entry name

Q8T4A9_DROME

Accession

Primary (citable) accession number: Q8T4A9
Secondary accession number(s): Q9VXB2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)