Unreviewed, UniProtKB/TrEMBL Q8T3K5 (Q8T3K5_DROME)

Names and origin

Protein names

Submitted name:
    4EHP EMBL AAF56233.2
Submitted name:
    SD07020p EMBL AAM11319.1

Gene names

Name:	4EHP FlyBase FBgn0053100
Synonyms:	Syx1A EMBL AAM11319.1
ORF Names:	CG33100 FlyBase FBgn0053100, Dmel_CG33100 EMBL AAF56233.2

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAM11319.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	223 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the eukaryotic initiation factor 4E family. RuleBase RU004374V0

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	RNA-binding RuleBase RU004374V0
Molecular function	Initiation factor RuleBase RU004374V0
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translational initiation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	RNA binding Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: IntAct translation initiation factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8T3K5-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: F6A96D4E17229DA1	FASTA	223	25,774
	10 20 30 40 50 60 MSMEKVANKQ YETKNWPDIV DSDDSDVDNQ IDVDNLPPLE VGPGENRLQH TYCLWFSRKE 70 80 90 100 110 120 TQRAAADYSK SLHMVGRCAS VQQWWSLYSH LIRPTALKPY RELLLFKQGI IPMWEDPANS 130 140 150 160 170 180 KGGQWLIRLR KNKVDRAWEN VCMAMLGEQF LVGDEICGVV LQTKYPEDSL SVWHRTATDM 190 200 210 220 TSTTRIRDTL RRILNIPLTT ALEYKIHCDS LKYVSINKGP LKS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[3]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014297 Genomic DNA. Translation: AAF56233.2. AY094966 mRNA. Translation: AAM11319.1.
RefSeq	NP_788729.1.
UniGene	Dm.33414
3D structure databases
HSSP	HSSP built from PDB template 1IPC based on UniProtKB P06730.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q8T3K5. 2 interactions.
Proteomic databases
PRIDE	Q8T3K5.
Genome annotation databases
Ensembl	FBgn0053100. Drosophila melanogaster. [Contig view]
GeneID	326255.
KEGG	dme:Dmel_CG33100.
NMPDR	fig|7227.3.peg.14360.
Organism-specific databases
FlyBase	FBgn0053100. 4EHP.
Phylogenomic databases
HOGENOM	Q8T3K5.
OMA	Q8T3K5. LWKPRLN.
Family and domain databases
InterPro	IPR001040. TIF_eIF_4E. [Graphical view]
Gene3D	G3DSA:3.30.760.10. TIF_eIF_4E. 1 hit.
PANTHER	PTHR11960. TIF_eIF_4E. 1 hit.
Pfam	PF01652. IF4E. 1 hit. [Graphical view]
ProDom	PD003697. TIF_eIF_4E. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...
Other Resources
NextBio	847868.

Entry information

Entry name

Q8T3K5_DROME

Accession

Primary (citable) accession number: Q8T3K5
Secondary accession number(s): Q9VCD6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	July 7, 2009
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)