Q8T3K2 (Q8T3K2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
SD08167p EMBL AAM11322.1

Gene names

Name:

RhoGAP15B EMBL AAM11322.1

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1226 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PH domain. SAAS SAAS000198 Contains 1 Rho-GAP domain. SAAS SAAS000198

Ontologies

Keywords
Molecular function	GTPase activation SAAS SAAS000198
Gene Ontology (GO)
Biological process	signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	GTPase activator activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8T3K2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: F73229649FA0B0D4	FASTA	1,226	139,048
	10 20 30 40 50 60 MDLDRRQTMP STEVFNTIQF SSPLNRNGGL PDLRENDAKL QKEDYLRLDP DQEDDGCYEV 70 80 90 100 110 120 PKTQGKPPSY DEALRSRPSP SDSPMSRNLA QEAAQLVQLR NQRQLSSSSS NGDESPRLPM 130 140 150 160 170 180 PAFPPPRLSQ QPEQFRMDAL QPPVRQKRRK NYEHIELRRP PVDSAQLEEL NRAAAAAERE 190 200 210 220 230 240 ESLLISAKNA EAETKTPKPE RSDSWEFYGE DENEEEDRDE EQEGSSAPEP VYANQEATYG 250 260 270 280 290 300 KLFEMATAGS SRSNVLTPNQ VAEQQQLACI TEDSELDACE GAVGGVPLPQ AVIEEFDPLS 310 320 330 340 350 360 SKCSTLARSN KSNELLLLEH LLEEDTYGTV KAEQDDVSMC TSEEEPTTSA ATSPKPQQPQ 370 380 390 400 410 420 IVHQNARLLS DSMENMLDSD QERAKPYLSR MPESANKASG PVDLASASRN RTNWFVPDKA 430 440 450 460 470 480 SCSDVTPNTS KTTPPIEGDS PPTYLEAIGG SKDAAGNQEN RSTIGSRFRQ TINAISNVKL 490 500 510 520 530 540 KMDAMKRKAS FRGANQRQSD VRVALQMVPR PSLSPLLIRY EGPLVRFPSG VVEDILKEMQ 550 560 570 580 590 600 NRKAILRERQ FQTFLDQEMK TPREMIPLDT ITTLQCVSNS RVTDTATHFY CFEITTSQPK 610 620 630 640 650 660 NGNGAGDAMS SNPNLLMTSS SSGNVKQQRV SHLYGVGKES ERGVWMQKIL ESLTNSLPVK 670 680 690 700 710 720 YTCHYYRAGW CYLKNSITSE WSGTWLVLRK SQRRLIFVSE ANGNVEKMDL RKARCIVLKE 730 740 750 760 770 780 SDESIDNLHV ESGPMLMIDC PPYAVYMIMS SARETKIWRH IIREVAHNNG FSLGDQQLTR 790 800 810 820 830 840 YDVPVIVDKC INFVYIHGSM SEGIYRKSGS ENSMHKLMSA FRADAFNVEI TRNEYNEHDV 850 860 870 880 890 900 ANVLKRFMRD LPERLLGKLT DSFVFVTELA VASEKIPIYR ELLARLSAIE RETLRRIVGH 910 920 930 940 950 960 LVFISSQQAK NKMSVQNLTM IWGPTLLAKK SDELIYSQKE ADVLSDLVVL YKNLFPCSAD 970 980 990 1000 1010 1020 EIKREQAMLA CLQKYYAAAE TLKDAVKQSG DIKIWISLNP NPENKTEEKT QVNATISPTK 1030 1040 1050 1060 1070 1080 TAYELCREYS AKMQLPTHQL TLYEVILNDS LERPLHHDTK VFDVILNWSY WPEEDRKHNY 1090 1100 1110 1120 1130 1140 LVVRPVEMLR EIQRAVKNLA TVTPGKELRF ADSRTKTFKT LQCELRDGKI VVSKKDKNDK 1150 1160 1170 1180 1190 1200 TTIVREIFLQ SSTAYLGCER KRDFPWSWAI TFVERTQAQI MRSRDAPFIG HVLAGSEWGD 1210 1220 RTIWYSSIWY CLYRDNILPP AEIIIK

References

[1]

Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY094969 mRNA. Translation: AAM11322.1.
3D structure databases
ProteinModelPortal	Q8T3K2.
SMR	Q8T3K2. Positions 665-766, 770-955.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8T3K2.
Proteomic databases
PRIDE	Q8T3K2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
UCSC	CG4937-RC. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0030808. RhoGAP15B.
Phylogenomic databases
eggNOG	inNOG04453.
GeneTree	EMGT00050000006112.
InParanoid	Q8T3K2.
Gene expression databases
ArrayExpress	Q8T3K2.
Bgee	Q8T3K2.
Family and domain databases
InterPro	IPR011993. PH_type. IPR001849. Pleckstrin_homology. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. [Graphical view]
Gene3D	G3DSA:2.30.29.30. PH_type. 2 hits. G3DSA:1.10.555.10. RhoGAP. 1 hit.
Pfam	PF00620. RhoGAP. 1 hit. [Graphical view]
SMART	SM00233. PH. 2 hits. SM00324. RhoGAP. 1 hit. [Graphical view]
SUPFAM	SSF48350. Rho_GAP. 1 hit.
PROSITE	PS50238. RHOGAP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q8T3K2_DROME

Accession

Primary (citable) accession number: Q8T3K2

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	November 16, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)