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Protein

Lysozyme B

Gene

alyB

Organism
Dictyostelium discoideum (Slime mold)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Has antibacterial activity.By similarity

Catalytic activityi

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

GO - Molecular functioni

  • lysozyme activity Source: UniProtKB

GO - Biological processi

  • cytolysis Source: UniProtKB-KW
  • defense response to Gram-positive bacterium Source: UniProtKB
  • peptidoglycan catabolic process Source: dictyBase

Keywordsi

Molecular functionAntibiotic, Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Lysozyme B (EC:3.2.1.17)
Alternative name(s):
1,4-beta-N-acetylmuramidase B
Gene namesi
Name:alyB
ORF Names:DDB_G0275119
OrganismiDictyostelium discoideum (Slime mold)
Taxonomic identifieri44689 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaMycetozoaDictyostelidsDictyostelialesDictyosteliaceaeDictyostelium
Proteomesi
  • UP000002195 Componentsi: Chromosome 2, Unassembled WGS sequence

Organism-specific databases

dictyBaseiDDB_G0275119 alyB

Subcellular locationi

GO - Cellular componenti

  • cytoplasmic vesicle Source: UniProtKB
  • cytoplasmic vesicle lumen Source: UniProtKB-SubCell
  • vesicle lumen Source: UniProtKB

Keywords - Cellular componenti

Cytoplasmic vesicle

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19By similarityAdd BLAST19
ChainiPRO_000031591620 – 138Lysozyme BAdd BLAST119
PropeptideiPRO_0000315917139 – 181By similarityAdd BLAST43

Post-translational modificationi

Contains six disulfide bonds.By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ8T1G6

Interactioni

Protein-protein interaction databases

STRINGi44689.DDB0231278

Structurei

3D structure databases

SMRiQ8T1G6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dictyostelium lysozyme family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ8T1G6
OMAiMWVEQNA
PhylomeDBiQ8T1G6

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8T1G6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRISFFLLIL AVIIGYAYGY SCPKPCYGNM CCSTSPGNKY YLTDFCGSTS
60 70 80 90 100
ACGPVPSCSG ALYFTADSQR FGCGKHLNLC RGSKCVKAQI YDAGPAMWVE
110 120 130 140 150
QDAGMMIIDA SPTICHVLTG GSSCGWSDKF EITATVTSLT DSRPLGPFNV
160 170 180
TEEEKAQLFI DHEIAMAQCE AEKTCNGFDL E
Length:181
Mass (Da):19,535
Last modified:June 1, 2002 - v1
Checksum:iC505C07DBE8E4580
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAFI02000013 Genomic DNA Translation: EAL69840.1
RefSeqiXP_643741.1, XM_638649.1

Genome annotation databases

EnsemblProtistsiEAL69840; EAL69840; DDB_G0275119
GeneIDi8619785
KEGGiddi:DDB_G0275119

Similar proteinsi

Entry informationi

Entry nameiLYSB_DICDI
AccessioniPrimary (citable) accession number: Q8T1G6
Secondary accession number(s): Q554H0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: June 1, 2002
Last modified: March 28, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome