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Protein

Angiotensin-converting enzyme

Gene

Ance-3

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:Ance-3Imported
Synonyms:ance-3Imported, BG:DS00180.5Imported, CG31766Imported, CG31843Imported, CT40163Imported, Dmel\CG17988Imported, DS00180.5Imported
ORF Names:CG17988Imported, Dmel_CG17988Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
Proteomesi
  • UP000000803 Componenti: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032536 Ance-3

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501509936822 – 844Angiotensin-converting enzymeSequence analysisAdd BLAST823

Keywords - PTMi

GlycoproteinUniRule annotation

Expressioni

Gene expression databases

BgeeiFBgn0032536

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0099733

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
GeneTreeiENSGT00520000055576
KOiK01283
OMAiICQASAW
OrthoDBiEOG091G033S

Family and domain databases

CDDicd06461 M2_ACE, 1 hit
InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Complete.

Q8SXX2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSVSLLGCL CLSLSLTLST GSPQLNLPTP QPEVFYNGYT PNVATTPAQL
60 70 80 90 100
RADRDRDQRY GPPYSDAGGG GNTDDGLDDF RFGQTDDERM RIGYGYPTPR
110 120 130 140 150
VNFSDSPFSG ARFSNHNYGP ISSTTERNYG NDANLNGRYS DVPYSSQGER
160 170 180 190 200
NFNPNDQYNY NNNPNVEFVG INNRNRFENP FLSNQDRFNL NQGYLERQRY
210 220 230 240 250
QQDRRYQQEL EKLRILLVES DQKGSLECTA NVAAQWNFET NVNDFTQTEA
260 270 280 290 300
LNAQQRYVEF QRITAEQSKR INKDLIFDRR LYRQLMLQSE VGPNALPLDV
310 320 330 340 350
LDRYNRLLNE MLFLYNSAEI CAYQQPFQCD LHYIPQLKDI MAKSRDWDEL
360 370 380 390 400
QHTWVEYHRK AGRGMRDSYE QLIDVMQEVA YVNNVTNGGE YWYLAYESGN
410 420 430 440 450
FRQDMDIVWE QIRPLYEGLH AYVRRKLRDY YGPDRINRIA PIPSHILGNM
460 470 480 490 500
YGQSWSNVLD ILIPYPGRKL IDVTPRMVEQ GYTPQLMFQL AEEFFTSINM
510 520 530 540 550
SAVGPEFYRN SIFEQPLDRR VLCEPSAWDF CNRHDFRVKI CTDINQRSLI
560 570 580 590 600
SVHHEMAHIQ YFLQYRHLPK IFRNGANPAF HQAVGDAIGL SVSTPRHLQT
610 620 630 640 650
LGLLQRSLDE SSYDINYLFT MAIDKVAFLP FALSLDNWRY DVFSGNANKR
660 670 680 690 700
TMNCHYWNLR EKYSGIKPPV LRSEKDFDPG AKYHIPANIP YIKYFFSTVL
710 720 730 740 750
QFQIYRGLCR ESGQYVPGDP RKPLHQCDIY RQPAAGNILK TLMSKGASQP
760 770 780 790 800
WQEVLEETLR EGRLDGTALR EYFAPLEEWL RQENLRTNEY VGWNYDGDYC
810 820 830 840
KRSIETAGLQ VFGGYYNGAT GQKSAPFLYP LILLIYLYFS LRLL
Length:844
Mass (Da):98,243
Last modified:June 1, 2002 - v1
Checksum:i46E1E123F5CC8F71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY075532 mRNA Translation: AAL68339.1
AE014134 Genomic DNA Translation: ABC65898.1
AE014134 Genomic DNA Translation: AHN54431.1
RefSeqiNP_001033904.1, NM_001038815.2
NP_001285917.1, NM_001298988.1
UniGeneiDm.5448

Genome annotation databases

EnsemblMetazoaiFBtr0100327; FBpp0099733; FBgn0032536
FBtr0343641; FBpp0310234; FBgn0032536
GeneIDi34808
KEGGidme:Dmel_CG17988
UCSCiCG17988-RB d. melanogaster

Similar proteinsi

Entry informationi

Entry nameiQ8SXX2_DROME
AccessioniPrimary (citable) accession number: Q8SXX2
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: June 20, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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