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Q8SXX2

- Q8SXX2_DROME

UniProt

Q8SXX2 - Q8SXX2_DROME

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Protein
Submitted name:

Ance-3, isoform B

Gene

Ance-3

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Cofactori

Protein has several cofactor binding sites:
  • Note: Binds 1 zinc ion per subunit.UniRule annotation
  • Note: Binds 2 zinc ions per subunit.UniRule annotation

GO - Molecular functioni

  1. carboxypeptidase activity Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. peptidyl-dipeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotationImported, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ance-3, isoform BImported (EC:3.4.15.-Imported)
Submitted name:
Ance-3, isoform CImported (EC:3.4.15.-Imported)
Submitted name:
RH06639pImported
Gene namesi
Name:Ance-3Imported
ORF Names:Dmel_CG17988Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
ProteomesiUP000000803: Chromosome 2L

Organism-specific databases

FlyBaseiFBgn0032536. Ance-3.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: FlyBase
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7227.FBpp0099733.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Phylogenomic databases

eggNOGiNOG71044.
GeneTreeiENSGT00520000055576.
KOiK01283.
OMAiICAYQQP.
OrthoDBiEOG7N37C7.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

Q8SXX2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHSVSLLGCL CLSLSLTLST GSPQLNLPTP QPEVFYNGYT PNVATTPAQL
60 70 80 90 100
RADRDRDQRY GPPYSDAGGG GNTDDGLDDF RFGQTDDERM RIGYGYPTPR
110 120 130 140 150
VNFSDSPFSG ARFSNHNYGP ISSTTERNYG NDANLNGRYS DVPYSSQGER
160 170 180 190 200
NFNPNDQYNY NNNPNVEFVG INNRNRFENP FLSNQDRFNL NQGYLERQRY
210 220 230 240 250
QQDRRYQQEL EKLRILLVES DQKGSLECTA NVAAQWNFET NVNDFTQTEA
260 270 280 290 300
LNAQQRYVEF QRITAEQSKR INKDLIFDRR LYRQLMLQSE VGPNALPLDV
310 320 330 340 350
LDRYNRLLNE MLFLYNSAEI CAYQQPFQCD LHYIPQLKDI MAKSRDWDEL
360 370 380 390 400
QHTWVEYHRK AGRGMRDSYE QLIDVMQEVA YVNNVTNGGE YWYLAYESGN
410 420 430 440 450
FRQDMDIVWE QIRPLYEGLH AYVRRKLRDY YGPDRINRIA PIPSHILGNM
460 470 480 490 500
YGQSWSNVLD ILIPYPGRKL IDVTPRMVEQ GYTPQLMFQL AEEFFTSINM
510 520 530 540 550
SAVGPEFYRN SIFEQPLDRR VLCEPSAWDF CNRHDFRVKI CTDINQRSLI
560 570 580 590 600
SVHHEMAHIQ YFLQYRHLPK IFRNGANPAF HQAVGDAIGL SVSTPRHLQT
610 620 630 640 650
LGLLQRSLDE SSYDINYLFT MAIDKVAFLP FALSLDNWRY DVFSGNANKR
660 670 680 690 700
TMNCHYWNLR EKYSGIKPPV LRSEKDFDPG AKYHIPANIP YIKYFFSTVL
710 720 730 740 750
QFQIYRGLCR ESGQYVPGDP RKPLHQCDIY RQPAAGNILK TLMSKGASQP
760 770 780 790 800
WQEVLEETLR EGRLDGTALR EYFAPLEEWL RQENLRTNEY VGWNYDGDYC
810 820 830 840
KRSIETAGLQ VFGGYYNGAT GQKSAPFLYP LILLIYLYFS LRLL
Length:844
Mass (Da):98,243
Last modified:June 1, 2002 - v1
Checksum:i46E1E123F5CC8F71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY075532 mRNA. Translation: AAL68339.1.
AE014134 Genomic DNA. Translation: ABC65898.1.
AE014134 Genomic DNA. Translation: AHN54431.1.
RefSeqiNP_001033904.1. NM_001038815.2.
UniGeneiDm.5448.

Genome annotation databases

EnsemblMetazoaiFBtr0100327; FBpp0099733; FBgn0032536.
GeneIDi34808.
KEGGidme:Dmel_CG17988.
UCSCiCG17988-RB. d. melanogaster.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY075532 mRNA. Translation: AAL68339.1 .
AE014134 Genomic DNA. Translation: ABC65898.1 .
AE014134 Genomic DNA. Translation: AHN54431.1 .
RefSeqi NP_001033904.1. NM_001038815.2.
UniGenei Dm.5448.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7227.FBpp0099733.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai FBtr0100327 ; FBpp0099733 ; FBgn0032536 .
GeneIDi 34808.
KEGGi dme:Dmel_CG17988.
UCSCi CG17988-RB. d. melanogaster.

Organism-specific databases

CTDi 34808.
FlyBasei FBgn0032536. Ance-3.

Phylogenomic databases

eggNOGi NOG71044.
GeneTreei ENSGT00520000055576.
KOi K01283.
OMAi ICAYQQP.
OrthoDBi EOG7N37C7.

Miscellaneous databases

GenomeRNAii 34808.
NextBioi 790323.

Family and domain databases

InterProi IPR001548. Peptidase_M2.
[Graphical view ]
PANTHERi PTHR10514. PTHR10514. 1 hit.
Pfami PF01401. Peptidase_M2. 1 hit.
[Graphical view ]
PRINTSi PR00791. PEPDIPTASEA.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Drosophila melanogaster."
    Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D.
    , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
    Science 287:2185-2195(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  3. Cited for: GENOME REANNOTATION.
    Strain: BerkeleyImported.
  4. "The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective."
    Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., Ashburner M., Celniker S.E.
    Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  5. "Heterochromatic sequences in a Drosophila whole-genome shotgun assembly."
    Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., Karpen G.H.
    Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BerkeleyImported.
  7. "Combined evidence annotation of transposable elements in genome sequences."
    Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., Ashburner M., Anxolabehere D.
    PLoS Comput. Biol. 1:166-175(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  8. Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., Svirskas R., Rubin G.
    Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  9. "Drosophila melanogaster release 4 sequence."
    Berkeley Drosophila Genome Project
    Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., Yu C., Rubin G.
    Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  10. "The Release 5.1 annotation of Drosophila melanogaster heterochromatin."
    Smith C.D., Shu S., Mungall C.J., Karpen G.H.
    Science 316:1586-1591(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BerkeleyImported.
  12. FlyBase
    Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ8SXX2_DROME
AccessioniPrimary (citable) accession number: Q8SXX2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: November 26, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3