Q8SXK2 (Q8SXK2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CG10092 EMBL AAF54156.2
EC=6.1.1.19 EMBL AAF54156.2

Submitted name:
RE18459p EMBL AAL90329.1

Gene names

ORF Names:

CG10092 FlyBase FBgn0037526 EMBL AAL90329.1, Dmel_CG10092 EMBL AAF54156.2

Organism

Drosophila melanogaster (Fruit fly) EMBL AAL90329.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	594 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489
Ligand	ATP-binding RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489 Ligase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	mitochondrion Inferred from direct assay. Source: FlyBase
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW arginine-tRNA ligase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q8SXK2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: B50284ACCE35702C	FASTA	594	68,326
	10 20 30 40 50 60 MERPHIGLFT YKICNALKEL TERMIRLRQA ICEQLPHLKN ACYALEVPVK KQQLQNSRRP 70 80 90 100 110 120 TVEWILPSAF AQQEVELLDS LKKRRFEAYV ENVRIVPSAG RSAAKIEFQL QPQVFVEQLL 130 140 150 160 170 180 QTKEIALHPS PFAAEHIVVE YSSPNIAKPF HVGHLRSTII GNVLANLHEH LGYRTTRLNY 190 200 210 220 230 240 LGDWGTQFGL LVLGVQLLNV SDKEMQLSPI ETLYKSYVAA NKAAEQRPEI AQQARDLFAA 250 260 270 280 290 300 LEGGTDKSMA KKWQQYRNYT IEDLSKVYNR LGVHFDSYEW ESQYSQQQIQ DVLDKLRSAG 310 320 330 340 350 360 LLQPEHDGRE IVVVDGRRIP VIKSNGSTLY LARDIAALLE RLSRFQFSRL LYVVDNGQAD 370 380 390 400 410 420 HFNALFKTTA ALDDRLSLEQ LQHVKFGRIY GMSTRQGKAI FLKDVLDEAR DIMREKRNIS 430 440 450 460 470 480 ATTRENYNLD DEHVCDILGV SAVLVNVLKQ RRQRDHEFSW QQALQVNGDT GIKLQYTHCR 490 500 510 520 530 540 LHSLLDNFRD VDLDDIKPDW KHFSTEPADA LDLLYALARF DQSVWQSKEQ LEACVLVNYL 550 560 570 580 590 FGLCNATSQA LKRLPVKQES SLEKQLQRLL LFHAAKKTLR HGMELLGLRP LNQM

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.
[2]	"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley.
[3]	Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S. Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Berkeley EMBL AAL90329.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE014297 Genomic DNA. Translation: AAF54156.2. AY089591 mRNA. Translation: AAL90329.1.
RefSeq	NP_649745.3. NM_141488.2.
UniGene	Dm.4936.
3D structure databases
HSSP	HSSP built from PDB template 1F7U based on UniProtKB Q05506.
ProteinModelPortal	Q8SXK2.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-977667.
Proteomic databases
PRIDE	Q8SXK2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	FBtr0081752; FBpp0081249; FBgn0037526.
GeneID	40929.
KEGG	dme:Dmel_CG10092.
NMPDR	fig|7227.3.peg.11604.
UCSC	CG10092-RA. d. melanogaster.
Organism-specific databases
FlyBase	FBgn0037526. CG10092.
Phylogenomic databases
eggNOG	inNOG04130.
GeneTree	EMGT00050000016586.
InParanoid	Q8SXK2.
OMA	TQFAMIA.
OrthoDB	EOG48GTK0.
PhylomeDB	Q8SXK2.
Gene expression databases
ArrayExpress	Q8SXK2.
Bgee	Q8SXK2.
Family and domain databases
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
KO	K01887.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. ArgS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	821333.

Entry information

Entry name

Q8SXK2_DROME

Accession

Primary (citable) accession number: Q8SXK2
Secondary accession number(s): Q9VHZ0

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2002
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 86 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)