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Q8SWH2 (HSP7A_ENCCU) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Heat shock protein ECU02_0100
Gene names
Ordered Locus Names:ECU02_0100
OrganismEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) [Reference proteome]
Taxonomic identifier284813 [NCBI]
Taxonomic lineageEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon

Protein attributes

Sequence length683 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm By similarity.

Developmental stage

Expressed in late sporogonial stages.

Sequence similarities

Belongs to the heat shock protein 70 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
Stress response
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to stress

Inferred from electronic annotation. Source: UniProtKB-KW

translation

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 683683Heat shock protein ECU02_0100
PRO_0000383324

Sequences

Sequence LengthMass (Da)Tools
Q8SWH2 [UniParc].

Last modified May 29, 2013. Version 2.
Checksum: 7574B929D04CF561

FASTA68375,802
        10         20         30         40         50         60 
MLVRGLLSAV ATIFCGAPKD TDLRESVAVG IDLGTTYSCI SVYSPSSKDT RFVLSPGGEE 

        70         80         90        100        110        120 
TYPSVVYFKK LPEGDGKKSK YEAVAGWPGL QMYNAEGNAN TYFYAFKRGM GIEDLANIDK 

       130        140        150        160        170        180 
KVEEIKRNAS VPIFVESVGG KKRVAYKIQE AMQDGYESVT PEELSSHVLR MLKDQIVKDY 

       190        200        210        220        230        240 
KIQGLTITVP AYFDVNQVAA TIKAAEMAGF PTPIIWKEPS AAAFAHTYDL IRKGITTKEE 

       250        260        270        280        290        300 
VDDMNICVFD LGGGTFDVSI VESSGGFMMV PSYGGNNFLG GENVNDNLTK YFADYIKSST 

       310        320        330        340        350        360 
GFDVMENQNV KLRLRNVVED MKRDLCDEVR KSPGRKANPS ISKSFIYDGE KSIVLELTNE 

       370        380        390        400        410        420 
KFNELNADFY SRIRKTMDSL LSGDGKDNKG YDKSLINRVL LVGGSTRIPK VIDIVEEIFG 

       430        440        450        460        470        480 
ANKIYSEGVN ADTIVARGAA LYTANSLNLL NESEQIVTAD SVPLSLGICT EEDHFEAIIS 

       490        500        510        520        530        540 
KGALLPATGT KEFTTAQDNQ TKVRIRVAQG GLESFKDNIY IGDIELDLPG NQPRGVPRIA 

       550        560        570        580        590        600 
VTLEIDTHGK IYVKAVDLQN NKEASSYFSS VVANMTSEEI ERFEERVHGE ENQELVKKRE 

       610        620        630        640        650        660 
VVRKLEQAIS QAESPKFAEV IPENIKKDAL EYVQKTRLWL EKHKEIAPRI HIEEKLQEFD 

       670        680 
NGMKEFLSSA KSGEEKEIGR EEL 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi."
Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F., Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P., Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J., Vivares C.P.
Nature 414:450-453(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GB-M1.
[2]"Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation."
Peyretaillade E., Goncalves O., Terrat S., Dugat-Bony E., Wincker P., Cornman R.S., Evans J.D., Delbac F., Peyret P.
BMC Genomics 10:607-607(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: GB-M1.
[3]"Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi (microsporidia): a reference map for proteins expressed in late sporogonial stages."
Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.
Proteomics 6:3625-3635(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL STAGE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL590442 Genomic DNA. Translation: CAD25041.2.
RefSeqNP_584537.1. NM_001040726.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING6035.ECU02_0100.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID858527.
KEGGecu:ECU02_0100.

Organism-specific databases

EuPathDBMicrosporidiaDB:ECU02_0100.

Phylogenomic databases

eggNOGCOG0443.
OrthoDBEOG78D7TR.

Family and domain databases

Gene3D2.60.34.10. 1 hit.
InterProIPR018181. Heat_shock_70_CS.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSPR00301. HEATSHOCK70.
SUPFAMSSF100920. SSF100920. 1 hit.
PROSITEPS00014. ER_TARGET. 1 hit.
PS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHSP7A_ENCCU
AccessionPrimary (citable) accession number: Q8SWH2
Entry history
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: May 29, 2013
Last modified: July 9, 2014
This is version 74 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families