Reviewed, UniProtKB/Swiss-Prot Q8SV19 (ADRX_ENCCU)

Names and origin

Protein names

Recommended name:
    Adrenodoxin homolog
Alternative name(s):
    Ferredoxin

Gene names

Ordered Locus Names:

ECU07_0600

Organism

Encephalitozoon cuniculi (Microsporidian parasite) [Complete proteome]

Taxonomic identifier

6035 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Microsporidia › Unikaryonidae › Encephalitozoon

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions By similarity.
Cofactor	Binds 1 2Fe-2S cluster By similarity.
Subcellular location	Mitosome.
Sequence similarities	Belongs to the adrenodoxin/putidaredoxin family. Contains 1 2Fe-2S ferredoxin-type domain.

Ontologies

Keywords
Biological process	Electron transport Transport
Cellular component	Mitosome
Ligand	2Fe-2S Iron Iron-sulfur Metal-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitosome Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 128	128	Adrenodoxin homolog		PRO_0000382938
Regions
	Domain	12 – 115	104	2Fe-2S ferredoxin-type
Sites
	Metal binding	50	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	56	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	59	1	Iron-sulfur (2Fe-2S) By similarity
	Metal binding	96	1	Iron-sulfur (2Fe-2S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8SV19-1 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: D22B4EEE19BAD3CF	FASTA	128	14,060
	10 20 30 40 50 60 MDMFSAPDRI PEQIRIFFKT MKQVVPAKAV CGSTVLDVAH KNGVDLEGAC EGNLACSTCH 70 80 90 100 110 120 VILEEPLYRK LGEPSDKEYD LIDQAFGATG TSRLGCQLRV DKSFENAVFT VPRATKNMAV DGFKPKPH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi." Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F., Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P., Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J., Vivares C.P. Nature 414:450-453(2001) [PubMed: 11719806] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GB-M1.
[2]	"Distinct localization patterns of two putative mitochondrial proteins in the microsporidian Encephalitozoon cuniculi." Williams B.A.P., Cali A., Takvorian P.M., Keeling P.J. J. Eukaryot. Microbiol. 55:131-133(2008) [PubMed: 18318866] [Abstract] Cited for: SUBCELLULAR LOCATION.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL590447 Genomic DNA. Translation: CAD25592.1.
RefSeq	NP_585988.1.
3D structure databases
HSSP	HSSP built from PDB template 1I7H based on UniProtKB P0A9R4.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8SV19.
Genome annotation databases
GeneID	859417.
GenomeReviews	Gene locus ECU07_0600 in contig AL590447_GR.
KEGG	ecu:ECU07_0600.
NMPDR	fig|6035.1.peg.891.
Phylogenomic databases
HOGENOM	Q8SV19.
OMA	LAMAHEY
OrthoDB	EOG9K9CW3
PhylomeDB	Q8SV19.
Family and domain databases
InterPro	IPR001055. Adrenodoxin. IPR012675. b-grasp_ferredoxin-like. IPR001041. Ferredoxin. [Graphical view]
Gene3D	G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit.
Pfam	PF00111. Fer2. 1 hit. [Graphical view]
PRINTS	PR00355. ADRENODOXIN.
PROSITE	PS51085. 2FE2S_FER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ADRX_ENCCU

Accession

Primary (citable) accession number: Q8SV19

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 1, 2009
Last sequence update:	June 1, 2002
Last modified:	November 24, 2009
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)