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Protein
Submitted name:

Phosphatidylinositol 4-kinase alpha type II

Gene

Pi4KIIalpha

Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • 1-phosphatidylinositol 4-kinase activity Source: FlyBase

GO - Biological processi

  • endosome organization Source: FlyBase
  • Golgi organization Source: FlyBase
  • phosphatidylinositol phosphorylation Source: FlyBase
  • protein localization to organelle Source: FlyBase
  • secretory granule localization Source: FlyBase
  • secretory granule organization Source: FlyBase

Keywordsi

Molecular functionKinaseImported, Transferase

Enzyme and pathway databases

ReactomeiR-DME-1483248. Synthesis of PIPs at the ER membrane.
R-DME-1660499. Synthesis of PIPs at the plasma membrane.
R-DME-1660514. Synthesis of PIPs at the Golgi membrane.
R-DME-1660516. Synthesis of PIPs at the early endosome membrane.

Names & Taxonomyi

Protein namesi
Submitted name:
Phosphatidylinositol 4-kinase alpha type IIImported
Submitted name:
Phosphatidylinositol 4-kinase type II alphaImported
Gene namesi
Name:Pi4KIIalphaImported
Synonyms:PI4KII alphaImported, Pi4KII-alphaImported
ORF Names:CG2929Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0037339. Pi4KIIalpha.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PeptideAtlasiQ8STF7.

Expressioni

Gene expression databases

BgeeiFBgn0037339.
ExpressionAtlasiQ8STF7. differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini292 – 663PI3K/PI4KInterPro annotationAdd BLAST372

Phylogenomic databases

eggNOGiKOG2381. Eukaryota.
ENOG410XP06. LUCA.
OrthoDBiEOG091G09F3.

Family and domain databases

InterProiView protein in InterPro
IPR000403. PI3/4_kinase_cat_dom.
PfamiView protein in Pfam
PF00454. PI3_PI4_kinase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8STF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGARDQTDP PLLQLEDEVD LIGDFAKDQP PPRNQLSPLL NGFESTSNQL
60 70 80 90 100
TTKVEINTVG MGKRKTRRRG KKAREPMLLS VDDEDDEEEA QEERNHTNGL
110 120 130 140 150
PPGEESAGGD AVIQKPQLDN LVMHYDDQID DEDGEEAVLL KRSSNPRNQR
160 170 180 190 200
LKGSAEDSID SSSQQPPIIC HIAPAKVASS ALTSPLKTTS HTALARHPHD
210 220 230 240 250
EADDICLVPE IDFEGMSTDA GSDNRESQPL LGGGNASHGS RISELLGGLG
260 270 280 290 300
RGHDHVEFVS NTFGDDPLFS EIVAKAEGAI ENGVLPERIY QGSSGSYFVK
310 320 330 340 350
DASHQCLAVF KPKDEEPYGR LNPKWTKWMH KLCCPCCFGR ACLIPNQGYL
360 370 380 390 400
SESGASLVDQ KLNLNVVPKT RVVRLVAESF NYARIDRQKA KLKKRIKEHY
410 420 430 440 450
PSAHFNRMSL PLKTGSFQLF VEGYKDADYW LRRFESEPLP PSVAKSFQLQ
460 470 480 490 500
FERLVVLDYI IRNTDRGNDN WLIKYVAPKI TTQVGGTGGR TMHGVVTPKL
510 520 530 540 550
PNALGASKIV DLNEPPQASP KPTTGGRPSN HLAGGAATSA QQDSSSLASS
560 570 580 590 600
EDEPSSRSPP TSEPDWNVVN SAFIRIAAID NGLAFPFKHP DSWRAYPYHW
610 620 630 640 650
AWLPQAKIPF SEEIKEQVLP QLSDMNFVEE ICTELLYLFQ QDRGFDKRLF
660 670 680 690 700
ERQMSVMRGQ ILNLTQALRD GKSPVQLVQM PAVIVERSSG SRFFSFTQRF
710
QNKSPFFSWW
Length:710
Mass (Da):79,010
Last modified:June 1, 2002 - v1
Checksum:i42CD737B491D876E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF498318 mRNA. Translation: AAM18079.1.
AJ440722 mRNA. Translation: CAD29429.1.

Similar proteinsi

Entry informationi

Entry nameiQ8STF7_DROME
AccessioniPrimary (citable) accession number: Q8STF7
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2002
Last sequence update: June 1, 2002
Last modified: February 28, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)