Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8SSL7

- AGM1_ENCCU

UniProt

Q8SSL7 - AGM1_ENCCU

Protein

Probable phosphoacetylglucosamine mutase

Gene

PCM1

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Interconverts GlcNAc-6-P and GlcNAc-1-P.By similarity

    Catalytic activityi

    N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.

    Cofactori

    Binds 1 magnesium ion per subunit.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei62 – 621Phosphoserine intermediateBy similarity
    Metal bindingi62 – 621Magnesium; via phosphate groupBy similarity
    Metal bindingi278 – 2781MagnesiumBy similarity
    Metal bindingi280 – 2801MagnesiumBy similarity
    Metal bindingi282 – 2821MagnesiumBy similarity

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. phosphoacetylglucosamine mutase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. UDP-N-acetylglucosamine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Ligandi

    Magnesium, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00113; UER00530.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable phosphoacetylglucosamine mutase (EC:5.4.2.3)
    Short name:
    PAGM
    Alternative name(s):
    Acetylglucosamine phosphomutase
    N-acetylglucosamine-phosphate mutase
    Gene namesi
    Name:PCM1
    Ordered Locus Names:ECU01_0650
    OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
    Taxonomic identifieri284813 [NCBI]
    Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
    ProteomesiUP000000819: Chromosome I

    Organism-specific databases

    EuPathDBiMicrosporidiaDB:ECU01_0650.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 530530Probable phosphoacetylglucosamine mutasePRO_0000381747Add
    BLAST

    Expressioni

    Developmental stagei

    Expressed in late sporogonial stages.1 Publication

    Interactioni

    Protein-protein interaction databases

    STRINGi6035.ECU01_0650.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8SSL7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the phosphohexose mutase family.Curated

    Phylogenomic databases

    eggNOGiCOG1109.
    HOGENOMiHOG000210027.
    KOiK01836.
    OMAiDIVRVYA.
    OrthoDBiEOG7V1G0D.

    Family and domain databases

    Gene3Di3.30.310.50. 1 hit.
    3.40.120.10. 2 hits.
    InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
    IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
    IPR005845. A-D-PHexomutase_a/b/a-II.
    IPR005843. A-D-PHexomutase_C.
    IPR016066. A-D-PHexomutase_CS.
    IPR016657. PAGM.
    [Graphical view]
    PfamiPF02878. PGM_PMM_I. 2 hits.
    PF02879. PGM_PMM_II. 1 hit.
    PF00408. PGM_PMM_IV. 1 hit.
    [Graphical view]
    PIRSFiPIRSF016408. PAGM. 1 hit.
    SUPFAMiSSF53738. SSF53738. 4 hits.
    SSF55957. SSF55957. 1 hit.
    PROSITEiPS00710. PGM_PMM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8SSL7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDNALIADEN LKKPSKPAYY GTAGYRSKTS DLNNILCRAS LIAYLRSTTF    50
    AGKIIGVMIT ASHNPVEYNG IKIIDHNGDM LDEVWEEYSD RIVNCDDEKL 100
    AREMKKILRS CSNQSELGEG VRGHVVLGRD TRDSGERLCN NIRSVLGKLN 150
    CTVDDYGVVT TPELHFLVRK CNTENRVVDK AEYMKNIAHN FNSLSSITKG 200
    NLRMMIDTAN GVADMKLKEL DGMLDGKLNY EVLNDPKGIL NLDCGADFVK 250
    TKKRAPRLEA LSSSGFSQAA NRICASFDGD VDRLIFFTGP KDTEIFDGDS 300
    QAVFLALYIR SLLDRIESRL SIGVVLSYYS NNAAVDVLPP ESFKVVMAQT 350
    GVKNFVSAAR EFDVGIYFEP NGHGSVCFSQ ACIDEIEKGS TKSHAILKIL 400
    ANLFDPCIGD ALANFVIFKA LMGSADDLRK FRENPSRLLT VKIVDKNSIK 450
    VDQKNQVIEP KELQDKIDVE ALSLGGRSFV RPSGTEDVVR VYAECPSEAD 500
    ADLLCLKVAQ HVYDMCNGIG DHPEIDYTSK 530
    Length:530
    Mass (Da):58,611
    Last modified:June 1, 2002 - v1
    Checksum:iE74F296E1F93C1B6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL391737 Genomic DNA. Translation: CAD24935.1.
    RefSeqiXP_965900.1. XM_960807.1.

    Genome annotation databases

    GeneIDi860240.
    KEGGiecu:ECU01_0650.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL391737 Genomic DNA. Translation: CAD24935.1 .
    RefSeqi XP_965900.1. XM_960807.1.

    3D structure databases

    ProteinModelPortali Q8SSL7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6035.ECU01_0650.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 860240.
    KEGGi ecu:ECU01_0650.

    Organism-specific databases

    EuPathDBi MicrosporidiaDB:ECU01_0650.

    Phylogenomic databases

    eggNOGi COG1109.
    HOGENOMi HOG000210027.
    KOi K01836.
    OMAi DIVRVYA.
    OrthoDBi EOG7V1G0D.

    Enzyme and pathway databases

    UniPathwayi UPA00113 ; UER00530 .

    Family and domain databases

    Gene3Di 3.30.310.50. 1 hit.
    3.40.120.10. 2 hits.
    InterProi IPR005844. A-D-PHexomutase_a/b/a-I.
    IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
    IPR005845. A-D-PHexomutase_a/b/a-II.
    IPR005843. A-D-PHexomutase_C.
    IPR016066. A-D-PHexomutase_CS.
    IPR016657. PAGM.
    [Graphical view ]
    Pfami PF02878. PGM_PMM_I. 2 hits.
    PF02879. PGM_PMM_II. 1 hit.
    PF00408. PGM_PMM_IV. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF016408. PAGM. 1 hit.
    SUPFAMi SSF53738. SSF53738. 4 hits.
    SSF55957. SSF55957. 1 hit.
    PROSITEi PS00710. PGM_PMM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome I of the amitochondriate intracellular parasite Encephalitozoon cuniculi (Microspora)."
      Peyret P., Katinka M.D., Duprat S., Duffieux F., Barbe V., Barbazanges M., Weissenbach J., Saurin W., Vivares C.P.
      Genome Res. 11:198-207(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GB-M1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GB-M1.
    3. "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi (microsporidia): a reference map for proteins expressed in late sporogonial stages."
      Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.
      Proteomics 6:3625-3635(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL STAGE.

    Entry informationi

    Entry nameiAGM1_ENCCU
    AccessioniPrimary (citable) accession number: Q8SSL7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 1, 2009
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3