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Q8SSE3

- Q8SSE3_ENCCU

UniProt

Q8SSE3 - Q8SSE3_ENCCU

Protein

DNA ligase

Gene

ECU02_1220

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:ECU02_1220Imported
    OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)Imported
    Taxonomic identifieri284813 [NCBI]
    Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
    ProteomesiUP000000819: Chromosome II

    Organism-specific databases

    EuPathDBiMicrosporidiaDB:ECU02_1220.

    Interactioni

    Protein-protein interaction databases

    STRINGi6035.ECU02_1220.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8SSE3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10747.
    OMAiLETWHAR.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8SSE3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKILFADFC TVLEKISMTS KRLEIQSIFT DYLRNIRETH PPSMAPALYL    50
    SIATVYPEYF NKELGVGENA LVGIVAEVTG KSSKGVRNEY SKEGDLGTIA 100
    MRCRVSQLLI PKTQLEVMDV FLGMRRVANE EGPRSSSSKK RIILGMMVKC 150
    SPLESKYLIR LIEGRLKIGL ALKTVLISLA NVFSDDKIDE IKAAFNRQPD 200
    IGRLADCLLE HGVEGLSTKF QVTPGIPLKP MLSNPSKDLT SAFKRVENKS 250
    FTCEYKYDGE RVQIHRFDSS VETFSRNSEK TTEKYPDLMG LYDVSDRDFI 300
    VDGEIVAYNQ KERRILPFQV LTTRKRKRVE SNKIEVHVCV FVFDLIYFDG 350
    RSWIDEPLEE RRRVLHSSFK EIDGKFHFAE FKDCETPEEA ETFFNKSVEN 400
    NFEGMMIKTL GSDATYLPSQ RSNKWIKIKK DYLESMSDSL DLVVMGAYYG 450
    KGRRAGFYGG FLLGVYNDEE EKFEALCKIG TGFDDSILSK LHEQLSSSLC 500
    SAPKNYSYKE SVKPDVWVEA KYVWEVRAAG ISLSPIYSAA WSKGEKGISL 550
    RFPRFIRERD DKDVREATTS SQAYQMYLDS KVEHSEEFY 589
    Length:589
    Mass (Da):67,303
    Last modified:June 1, 2002 - v1
    Checksum:i4B8FEEDF085B41ED
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590442 Genomic DNA. Translation: CAD25151.1.
    RefSeqiNP_584647.1. NM_001040836.1.

    Genome annotation databases

    GeneIDi858637.
    KEGGiecu:ECU02_1220.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL590442 Genomic DNA. Translation: CAD25151.1 .
    RefSeqi NP_584647.1. NM_001040836.1.

    3D structure databases

    ProteinModelPortali Q8SSE3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 6035.ECU02_1220.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 858637.
    KEGGi ecu:ECU02_1220.

    Organism-specific databases

    EuPathDBi MicrosporidiaDB:ECU02_1220.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10747.
    OMAi LETWHAR.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GB-M1Imported.

    Entry informationi

    Entry nameiQ8SSE3_ENCCU
    AccessioniPrimary (citable) accession number: Q8SSE3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3