Q8SS83 (KCY_ENCCU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable cytidylate kinase
Short name=CK
EC=2.7.4.25

Alternative name(s):
Cytidine monophosphate kinase
Short name=CMP kinase

Gene names

Ordered Locus Names:

ECU03_1270

Organism

Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)

Taxonomic identifier

284813 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Microsporidia › Unikaryonidae › Encephalitozoon

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (d)CMP = ADP + (d)CDP.
Sequence similarities	Belongs to the cytidylate kinase family. Type 1 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW cytidylate kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Probable cytidylate kinase		PRO_0000388422
Regions
	Nucleotide binding	10 – 18	9	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8SS83 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: 26FC9F0D996E6528	FASTA	220	25,208
	10 20 30 40 50 60 MKTYKIAVDG PAASGKSSTS DLVARKLGFS HLISGNLYRA VTYGLVRRFG EVRPGDEEQK 70 80 90 100 110 120 RFVLELSIEV RNNRVFLDGE DVSESLRKEV VDRHVVSVAR EKYIREKVFT IQRSVIDLEK 130 140 150 160 170 180 RGIVVDGRDI ATRIMPNADL KVFLTASPET RARRRYMEGG SESYEELLES IKKRDHNDRT 190 200 210 220 REHDPLVATC DSIVIENDSM TLEETADEII RLFRRVESFN

References

[1]

"Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi." Katinka M.D., Duprat S., Cornillot E., Metenier G., Thomarat F., Prensier G., Barbe V., Peyretaillade E., Brottier P., Wincker P., Delbac F., El Alaoui H., Peyret P., Saurin W., Gouy M., Weissenbach J., Vivares C.P. Nature 414:450-453(2001) [PubMed: 11719806] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GB-M1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL590443 Genomic DNA. Translation: CAD26270.1.
RefSeq	NP_597635.1. NM_001040999.1.
3D structure databases
HSSP	HSSP built from PDB template 1Q3T based on UniProtKB Q97PK6.
ProteinModelPortal	Q8SS83.
ModBase	Search...
Protein-protein interaction databases
STRING	Q8SS83.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	858797.
GenomeReviews	Gene locus ECU03_1270 in contig AL590443_GR.
KEGG	ecu:ECU03_1270.
NMPDR	fig|6035.1.peg.280.
Organism-specific databases
EuPathDB	EupathDB:ECU03_1270.
Phylogenomic databases
eggNOG	COG0283.
HOGENOM	HBG354377.
OMA	DIGTVIC.
Family and domain databases
InterPro	IPR003136. Cytidylate_kin. IPR011994. Cytidylate_kinase_dom. [Graphical view]
KO	K00945.
PANTHER	PTHR21299:SF2. Cytidylate_kin. 1 hit.
Pfam	PF02224. Cytidylate_kin. 1 hit. [Graphical view]
TIGRFAMs	TIGR00017. Cmk. 1 hit.
ProtoNet	Search...

Entry information

Entry name

KCY_ENCCU

Accession

Primary (citable) accession number: Q8SS83

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 3, 2009
Last sequence update:	June 1, 2002
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program