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Q8SRT0

- PTP2_ENCCU

UniProt

Q8SRT0 - PTP2_ENCCU

Protein

Polar tube protein 2

Gene

PTP2

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Involved in formation of a polar tube through which the infectious agent is passed on to the host cell.

    GO - Biological processi

    1. sporulation resulting in formation of a cellular spore Source: UniProtKB-KW

    Keywords - Biological processi

    Sporulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Polar tube protein 2
    Gene namesi
    Name:PTP2
    Ordered Locus Names:ECU06_0240
    OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
    Taxonomic identifieri284813 [NCBI]
    Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
    ProteomesiUP000000819: Chromosome VI

    Organism-specific databases

    EuPathDBiMicrosporidiaDB:ECU06_0240.

    Subcellular locationi

    Spore polar tube 1 Publication

    GO - Cellular componenti

    1. polar tube Source: UniProtKB-SubCell

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1818Sequence AnalysisAdd
    BLAST
    Chaini19 – 277259Polar tube protein 2PRO_0000377525Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi134 – 1341N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Developmental stagei

    Expressed in late sporogonial stages.1 Publication

    Interactioni

    Subunit structurei

    Interacts with PTP1 and PTP3.1 Publication

    Family & Domainsi

    Keywords - Domaini

    Repeat, Signal

    Phylogenomic databases

    HOGENOMiHOG000115779.
    OrthoDBiEOG708W9M.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8SRT0-1 [UniParc]FASTAAdd to Basket

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    MLLLLAITAV VSATMVHPSA VVPQPAAPLH VVPPQQQMGM VNGCTSKKLE    50
    GAEIMRRNMI ECQKRSSEAT KAMIERANEK AVESFNKEVS KGPSQKDGGQ 100
    CIEKAVQGTD RCILAGIIDK AVNKRKYRIS DVENSTSLYR GDKLIALIVN 150
    VDYGLQPITK PKKKKSKIMA NLPQPKREMY FNQIGQLVGA RGTFPQENKE 200
    DCKPCEGPKK TVETTSEKCN LGCELKGTSA LISKAIQKKE VKDTKEGEKS 250
    ASQDSDGEGT AEDAEVQQPS ADGEGLE 277
    Length:277
    Mass (Da):30,076
    Last modified:June 1, 2002 - v1
    Checksum:i75FADFE9E706641E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AX007050 Genomic DNA. No translation available.
    AL590446 Genomic DNA. Translation: CAD25384.1.
    RefSeqiNP_585780.1. NM_001041402.1.

    Genome annotation databases

    GeneIDi859203.
    KEGGiecu:ECU06_0240.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AX007050 Genomic DNA. No translation available.
    AL590446 Genomic DNA. Translation: CAD25384.1 .
    RefSeqi NP_585780.1. NM_001041402.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 859203.
    KEGGi ecu:ECU06_0240.

    Organism-specific databases

    EuPathDBi MicrosporidiaDB:ECU06_0240.

    Phylogenomic databases

    HOGENOMi HOG000115779.
    OrthoDBi EOG708W9M.

    Family and domain databases

    ProtoNeti Search...

    Publicationsi

    1. "Microsporidian invasion apparatus: identification of a novel polar tube protein and evidence for clustering of ptp1 and ptp2 genes in three Encephalitozoon species."
      Delbac F., Peuvel I., Metenier G., Peyretaillade E., Vivares C.P.
      Infect. Immun. 69:1016-1024(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 105-119, SUBCELLULAR LOCATION.
    2. "Microsporidium polar tube proteins, nucleic acids coding for said proteins and their uses."
      Vivares C.P., Danchin A., Delbac F.
      Patent number WO0001724, 13-JAN-2000
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GB-M1.
    4. "The microsporidian polar tube: evidence for a third polar tube protein (PTP3) in Encephalitozoon cuniculi."
      Peuvel I., Peyret P., Metenier G., Vivares C.P., Delbac F.
      Mol. Biochem. Parasitol. 122:69-80(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH PTP1 AND PTP3.
    5. "Proteomic analysis of the eukaryotic parasite Encephalitozoon cuniculi (microsporidia): a reference map for proteins expressed in late sporogonial stages."
      Brosson D., Kuhn L., Delbac F., Garin J., Vivares C.P., Texier C.
      Proteomics 6:3625-3635(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], DEVELOPMENTAL STAGE.

    Entry informationi

    Entry nameiPTP2_ENCCU
    AccessioniPrimary (citable) accession number: Q8SRT0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 16, 2009
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    External Data

    Dasty 3