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Protein

Polar tube protein 2

Gene

PTP2

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Involved in formation of a polar tube through which the infectious agent is passed on to the host cell.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sporulation

Names & Taxonomyi

Protein namesi
Recommended name:
Polar tube protein 2
Gene namesi
Name:PTP2
Ordered Locus Names:ECU06_0240
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
Proteomesi
  • UP000000819 Componenti: Chromosome VI

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU06_0240.

Subcellular locationi

GO - Cellular componenti

  • polar tube Source: CACAO
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_000037752519 – 277Polar tube protein 2Add BLAST259

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi134N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Expressioni

Developmental stagei

Expressed in late sporogonial stages.1 Publication

Interactioni

Subunit structurei

Interacts with PTP1 and PTP3.1 Publication

Family & Domainsi

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

HOGENOMiHOG000115779.
InParanoidiQ8SRT0.
OrthoDBiEOG092C4ETT.

Family and domain databases

InterProiIPR031507. PTP2.
[Graphical view]
PfamiPF17022. PTP2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8SRT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLLLAITAV VSATMVHPSA VVPQPAAPLH VVPPQQQMGM VNGCTSKKLE
60 70 80 90 100
GAEIMRRNMI ECQKRSSEAT KAMIERANEK AVESFNKEVS KGPSQKDGGQ
110 120 130 140 150
CIEKAVQGTD RCILAGIIDK AVNKRKYRIS DVENSTSLYR GDKLIALIVN
160 170 180 190 200
VDYGLQPITK PKKKKSKIMA NLPQPKREMY FNQIGQLVGA RGTFPQENKE
210 220 230 240 250
DCKPCEGPKK TVETTSEKCN LGCELKGTSA LISKAIQKKE VKDTKEGEKS
260 270
ASQDSDGEGT AEDAEVQQPS ADGEGLE
Length:277
Mass (Da):30,076
Last modified:June 1, 2002 - v1
Checksum:i75FADFE9E706641E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AX007050 Genomic DNA. No translation available.
AL590446 Genomic DNA. Translation: CAD25384.1.
RefSeqiNP_585780.1. NM_001041402.1.

Genome annotation databases

EnsemblFungiiCAD25384; CAD25384; CAD25384.
GeneIDi859203.
KEGGiecu:ECU06_0240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AX007050 Genomic DNA. No translation available.
AL590446 Genomic DNA. Translation: CAD25384.1.
RefSeqiNP_585780.1. NM_001041402.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAD25384; CAD25384; CAD25384.
GeneIDi859203.
KEGGiecu:ECU06_0240.

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU06_0240.

Phylogenomic databases

HOGENOMiHOG000115779.
InParanoidiQ8SRT0.
OrthoDBiEOG092C4ETT.

Family and domain databases

InterProiIPR031507. PTP2.
[Graphical view]
PfamiPF17022. PTP2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTP2_ENCCU
AccessioniPrimary (citable) accession number: Q8SRT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.