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Q8SRF5

- Y823_ENCCU

UniProt

Q8SRF5 - Y823_ENCCU

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Protein
Probable cell division protein kinase ECU08_0230
Gene
ECU08_0230
Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

May play a role in the control of the eukaryotic cell cycle By similarity.1 Publication

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATP By similarity
Active sitei121 – 1211Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. mitotic nuclear division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cell division protein kinase ECU08_0230 (EC:2.7.11.22)
Gene namesi
Ordered Locus Names:ECU08_0230
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
ProteomesiUP000000819: Chromosome VIII

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU08_0230.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265Probable cell division protein kinase ECU08_0230
PRO_0000385505Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi6035.ECU08_0230.

Structurei

3D structure databases

ProteinModelPortaliQ8SRF5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 263260Protein kinase
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
OMAiLDECGGE.
OrthoDBiEOG7K3TWD.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8SRF5-1 [UniParc]FASTAAdd to Basket

« Hide

MTRYILGALI GSGTYGEVYE AIDTETKEKV ALKRIRLNEK EGMPGTALRE    50
ISILKKLSHR NIISLVSIIH TDALLTMVFP FIDYELKKYI GMNTGKNIME 100
LVNQLICGVH YLHRMNVVHR DLKPQNILVT SDGVLKIADF GLSRSLEIRV 150
PPYSSEVVTL WYRSPELLMG STSYRFYVDI WSLGCIIYEM ITLEPLFPGE 200
SKENQLTLIR RKAGTRRSLR GMVEQRLAVP KFVTEIIVRC LDFNYNQRIT 250
ADEIMEILEN EYGAC 265
Length:265
Mass (Da):30,400
Last modified:June 1, 2002 - v1
Checksum:i18E742DF03CB56D1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590448 Genomic DNA. Translation: CAD26328.1.
RefSeqiNP_597152.1. NM_001041761.1.

Genome annotation databases

GeneIDi859574.
KEGGiecu:ECU08_0230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590448 Genomic DNA. Translation: CAD26328.1 .
RefSeqi NP_597152.1. NM_001041761.1.

3D structure databases

ProteinModelPortali Q8SRF5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6035.ECU08_0230.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 859574.
KEGGi ecu:ECU08_0230.

Organism-specific databases

EuPathDBi MicrosporidiaDB:ECU08_0230.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
OMAi LDECGGE.
OrthoDBi EOG7K3TWD.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GB-M1.
  2. "The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe."
    Miranda-Saavedra D., Stark M.J.R., Packer J.C., Vivares C.P., Doerig C., Barton G.J.
    BMC Genomics 8:309-309(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PREDICTION OF FUNCTION.

Entry informationi

Entry nameiY823_ENCCU
AccessioniPrimary (citable) accession number: Q8SRF5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 1, 2002
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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