Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Arginine--tRNA ligase

Gene

ECU08_0550

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Ordered Locus Names:ECU08_0550
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
Proteomesi
  • UP000000819 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU08_0550

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003831421 – 563Arginine--tRNA ligaseAdd BLAST563

Proteomic databases

PRIDEiQ8SRD8

Expressioni

Developmental stagei

Expressed in late sporogonial stages.1 Publication

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi284813.NP_597184.1

Structurei

3D structure databases

ProteinModelPortaliQ8SRD8
SMRiQ8SRD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1195 Eukaryota
COG0018 LUCA
HOGENOMiHOG000247211
InParanoidiQ8SRD8
KOiK01887
OMAiALCVFFD
OrthoDBiEOG092C0Z3M

Family and domain databases

Gene3Di3.40.50.6201 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q8SRD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNELFRKVV EAISKASKFT PEEIAACMER SYQPKKPNVT LFLDRISPSP
60 70 80 90 100
QEDAKELLET LAGANIELIE NLAIRKSSVC CDINKRAILK DVLGYIQKNR
110 120 130 140 150
EIFGNNNVGK GKRMVVEYSS PNIAKIFHIG HLRTTVLGQF IVNLLRASGY
160 170 180 190 200
ETTSINYFGD WGKQFGFVLL GYSKYGSEEE LEKDPLKHLF NVYVKISADA
210 220 230 240 250
EKNPDVDSEA KEIFRMMEED KDEWCMNLWR RFRELSIEKY KVLYKRLNVE
260 270 280 290 300
FDVYSGESMY NEKGKSIVET SKQIKTDEDG SKVFDLGKAG KVLVMKNDGT
310 320 330 340 350
TLYITRDIAA AIERLEEYSP EKIIYVVSSE QNKHFEDLFG VLEMLGYDKD
360 370 380 390 400
KFQHVSYGLV AGMSTRAGKV QLLEDIIQES TEVMKNVMMS DNNKGSFTAA
410 420 430 440 450
EMDQTAEVLA ISTLLVMDFT ARRVKGYEFD IEKRARNTSG TGLYLQYAHC
460 470 480 490 500
RLRSIETKNS NVDYNDIETI DFELIHVPKV LNLVYKLLWF EHVVEKCLED
510 520 530 540 550
YEPSRIVTYL QDLASSINGA INILRVLGVD KELARARLLV LSSARIVLHN
560
GLRILGATPL NKM
Length:563
Mass (Da):64,253
Last modified:June 1, 2002 - v1
Checksum:iF6E50A60D4D4BB50
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590448 Genomic DNA Translation: CAD26360.1
RefSeqiNP_597184.1, NM_001041793.1

Genome annotation databases

EnsemblFungiiCAD26360; CAD26360; CAD26360
GeneIDi859606
KEGGiecu:ECU08_0550

Similar proteinsi

Entry informationi

Entry nameiSYR_ENCCU
AccessioniPrimary (citable) accession number: Q8SRD8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: June 1, 2002
Last modified: March 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome