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Protein

Probable cell division protein kinase ECU11_1290

Gene

ECU08_1790

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May play a role in the control of the eukaryotic cell cycle.By similarity

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei124Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cell division protein kinase ECU11_1290 (EC:2.7.11.22)
Gene namesi
Ordered Locus Names:ECU08_1790
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
Proteomesi
  • UP000000819 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU08_1790.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003855111 – 309Probable cell division protein kinase ECU11_1290Add BLAST309

Interactioni

Protein-protein interaction databases

STRINGi284813.NP_597307.1.

Structurei

3D structure databases

ProteinModelPortaliQ8SR90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 288Protein kinasePROSITE-ProRule annotationAdd BLAST285

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0600. Eukaryota.
ENOG410XPIR. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ8SR90.
OMAiDNEREGA.
OrthoDBiEOG092C2FL8.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8SR90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKYENIKQV GEGAFGQVYK SRRTSDGAVF AIKKMPVDRE TGFPFTAIRE
60 70 80 90 100
IKLCKSVINK HIIGLDEIVF EEGFIFVVLE YMPYDLTGLL ASGAKLSTDQ
110 120 130 140 150
IRSITSQLIE AVSSMHGMGL VHRDIKPSNI LLDCHGMLKL TDFGLTREIS
160 170 180 190 200
GMMTNRVCTL WYRAPELLLG ETSYSLKVDA WSVGCIMLEM RLGRPPYRGS
210 220 230 240 250
DEVSQIKLIF EELGIPQDKY KWSDLLDVDI YSKSRSTEEI IAERYGHLFD
260 270 280 290 300
EEELKVLSGF LCLTSRKRLS VANSRYFTVI SSHKNTYIPL SFEEAHELYT

KERKETKKP
Length:309
Mass (Da):35,280
Last modified:June 1, 2002 - v1
Checksum:iB18CD96414263A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590448 Genomic DNA. Translation: CAD26483.1.
RefSeqiNP_597307.1. NM_001041916.1.

Genome annotation databases

EnsemblFungiiCAD26483; CAD26483; CAD26483.
GeneIDi859729.
KEGGiecu:ECU08_1790.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590448 Genomic DNA. Translation: CAD26483.1.
RefSeqiNP_597307.1. NM_001041916.1.

3D structure databases

ProteinModelPortaliQ8SR90.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284813.NP_597307.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAD26483; CAD26483; CAD26483.
GeneIDi859729.
KEGGiecu:ECU08_1790.

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU08_1790.

Phylogenomic databases

eggNOGiKOG0600. Eukaryota.
ENOG410XPIR. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ8SR90.
OMAiDNEREGA.
OrthoDBiEOG092C2FL8.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiY8H9_ENCCU
AccessioniPrimary (citable) accession number: Q8SR90
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.