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Protein

Probable cell division protein kinase ECU11_1290

Gene

ECU08_1790

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May play a role in the control of the eukaryotic cell cycle.By similarity

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei33ATPPROSITE-ProRule annotation1
Active sitei124Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 18ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processCell cycle, Cell division, Mitosis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cell division protein kinase ECU11_1290 (EC:2.7.11.22)
Gene namesi
Ordered Locus Names:ECU08_1790
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMicrosporidiaUnikaryonidaeEncephalitozoon
Proteomesi
  • UP000000819 Componenti: Chromosome VIII

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU08_1790

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003855111 – 309Probable cell division protein kinase ECU11_1290Add BLAST309

Proteomic databases

PRIDEiQ8SR90

Interactioni

Protein-protein interaction databases

STRINGi284813.NP_597307.1

Structurei

3D structure databases

ProteinModelPortaliQ8SR90
SMRiQ8SR90
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 288Protein kinasePROSITE-ProRule annotationAdd BLAST285

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0600 Eukaryota
ENOG410XPIR LUCA
HOGENOMiHOG000233024
InParanoidiQ8SR90
OMAiDENMAEP
OrthoDBiEOG092C2FL8

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q8SR90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKYENIKQV GEGAFGQVYK SRRTSDGAVF AIKKMPVDRE TGFPFTAIRE
60 70 80 90 100
IKLCKSVINK HIIGLDEIVF EEGFIFVVLE YMPYDLTGLL ASGAKLSTDQ
110 120 130 140 150
IRSITSQLIE AVSSMHGMGL VHRDIKPSNI LLDCHGMLKL TDFGLTREIS
160 170 180 190 200
GMMTNRVCTL WYRAPELLLG ETSYSLKVDA WSVGCIMLEM RLGRPPYRGS
210 220 230 240 250
DEVSQIKLIF EELGIPQDKY KWSDLLDVDI YSKSRSTEEI IAERYGHLFD
260 270 280 290 300
EEELKVLSGF LCLTSRKRLS VANSRYFTVI SSHKNTYIPL SFEEAHELYT

KERKETKKP
Length:309
Mass (Da):35,280
Last modified:June 1, 2002 - v1
Checksum:iB18CD96414263A32
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590448 Genomic DNA Translation: CAD26483.1
RefSeqiNP_597307.1, NM_001041916.1

Genome annotation databases

EnsemblFungiiCAD26483; CAD26483; CAD26483
GeneIDi859729
KEGGiecu:ECU08_1790

Similar proteinsi

Entry informationi

Entry nameiY8H9_ENCCU
AccessioniPrimary (citable) accession number: Q8SR90
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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