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Q8SR10

- SYQ_ENCCU

UniProt

Q8SR10 - SYQ_ENCCU

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Protein
Probable glutamine--tRNA ligase
Gene
ECU10_1460
Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei444 – 4441ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Ordered Locus Names:ECU10_1460
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
ProteomesiUP000000819: Chromosome X

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU10_1460.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 697697Probable glutamine--tRNA ligase
PRO_0000388381Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi6035.ECU10_1460.

Structurei

3D structure databases

ProteinModelPortaliQ8SR10.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi204 – 21411"HIGH" region By similarity
Add
BLAST
Motifi441 – 4455"KMSKS" region By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259233.
KOiK01886.
OMAiRMQKRAK.
OrthoDBiEOG7MD4ZK.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8SR10-1 [UniParc]FASTAAdd to Basket

« Hide

MADLEKILER LGISPEKRCQ VIKKEQVVRN MEKIFLGRDL SNRLLYTLAC    50
IAPKNADLGL LADLVDARVI KHESMLKECL RYTEKKDVSM EEMTRFVKRN 100
EVSSEDVRKF VAKMRSDRVA KKDMVSKARK AMPCADFRVV VEEINKVPDD 150
VDGGDEKRPL EGGWLEEGEI KKLPKPSEIP QINEEIRQAH LRRTGGRVVT 200
RFPPEPNGIL HIGHAKAINL NFEYAKKFGG YTYLRYDDTN PKNEEAEYFD 250
SIYEDVRWLG FEPYKVTASS DYFDKMTEFG FQLIRKGKAY VCHLSQDEIC 300
ERRRQYVSDG TNDRSHLSQY RDRPVSENLR LFQEMVDGKW EEGKACLRFK 350
MDTDTKNPLM LDLVGIRILD VVHPRKNVKY TVYPTYEFAL CVSDSLEDVT 400
HSFCTREFYT RQESYNWLLV QLEIYKPIQW EFSRLNISNT VLSKRKLLPL 450
KKYGIELDDP RLFTIKGMRR RGFPPEAINQ FCRSLGFTFA ETTVDVKKLE 500
NFVRDNLNRT SRRIMCVKEP LKVTIMNSTP CSISIPDLPG SSVVRDVPFT 550
PVIYIEKSDF MEKGDKDFLR LTPEQPVGLY MLYPIRVVKV TPDGIVAERW 600
DGVPRKFIHW VSEDSVEVEM RMYSSLWTSF SPKDATYLEE MNKDSLKVFH 650
GLCDKRISDA RIEDRFQFQR IGYFCVDKDT TKENIVVNLT IPLKNIA 697
Length:697
Mass (Da):81,248
Last modified:June 1, 2002 - v1
Checksum:i045C9353A142AE04
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590449 Genomic DNA. Translation: CAD25865.1.
RefSeqiNP_586261.1. NM_001042094.1.

Genome annotation databases

GeneIDi859911.
KEGGiecu:ECU10_1460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590449 Genomic DNA. Translation: CAD25865.1 .
RefSeqi NP_586261.1. NM_001042094.1.

3D structure databases

ProteinModelPortali Q8SR10.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6035.ECU10_1460.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 859911.
KEGGi ecu:ECU10_1460.

Organism-specific databases

EuPathDBi MicrosporidiaDB:ECU10_1460.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000259233.
KOi K01886.
OMAi RMQKRAK.
OrthoDBi EOG7MD4ZK.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00440. glnS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GB-M1.

Entry informationi

Entry nameiSYQ_ENCCU
AccessioniPrimary (citable) accession number: Q8SR10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: June 1, 2002
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi