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Q8SR10

- SYQ_ENCCU

UniProt

Q8SR10 - SYQ_ENCCU

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Protein

Probable glutamine--tRNA ligase

Gene

ECU10_1460

Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei444 – 4441ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutamine-tRNA ligase activity Source: UniProtKB-EC

GO - Biological processi

  1. glutaminyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamine--tRNA ligase (EC:6.1.1.18)
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name:
GlnRS
Gene namesi
Ordered Locus Names:ECU10_1460
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
ProteomesiUP000000819: Chromosome X

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU10_1460.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 697697Probable glutamine--tRNA ligasePRO_0000388381Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi6035.ECU10_1460.

Structurei

3D structure databases

ProteinModelPortaliQ8SR10.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi204 – 21411"HIGH" regionBy similarityAdd
BLAST
Motifi441 – 4455"KMSKS" regionBy similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259233.
InParanoidiQ8SR10.
KOiK01886.
OMAiRMQKRAK.
OrthoDBiEOG7MD4ZK.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8SR10-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADLEKILER LGISPEKRCQ VIKKEQVVRN MEKIFLGRDL SNRLLYTLAC
60 70 80 90 100
IAPKNADLGL LADLVDARVI KHESMLKECL RYTEKKDVSM EEMTRFVKRN
110 120 130 140 150
EVSSEDVRKF VAKMRSDRVA KKDMVSKARK AMPCADFRVV VEEINKVPDD
160 170 180 190 200
VDGGDEKRPL EGGWLEEGEI KKLPKPSEIP QINEEIRQAH LRRTGGRVVT
210 220 230 240 250
RFPPEPNGIL HIGHAKAINL NFEYAKKFGG YTYLRYDDTN PKNEEAEYFD
260 270 280 290 300
SIYEDVRWLG FEPYKVTASS DYFDKMTEFG FQLIRKGKAY VCHLSQDEIC
310 320 330 340 350
ERRRQYVSDG TNDRSHLSQY RDRPVSENLR LFQEMVDGKW EEGKACLRFK
360 370 380 390 400
MDTDTKNPLM LDLVGIRILD VVHPRKNVKY TVYPTYEFAL CVSDSLEDVT
410 420 430 440 450
HSFCTREFYT RQESYNWLLV QLEIYKPIQW EFSRLNISNT VLSKRKLLPL
460 470 480 490 500
KKYGIELDDP RLFTIKGMRR RGFPPEAINQ FCRSLGFTFA ETTVDVKKLE
510 520 530 540 550
NFVRDNLNRT SRRIMCVKEP LKVTIMNSTP CSISIPDLPG SSVVRDVPFT
560 570 580 590 600
PVIYIEKSDF MEKGDKDFLR LTPEQPVGLY MLYPIRVVKV TPDGIVAERW
610 620 630 640 650
DGVPRKFIHW VSEDSVEVEM RMYSSLWTSF SPKDATYLEE MNKDSLKVFH
660 670 680 690
GLCDKRISDA RIEDRFQFQR IGYFCVDKDT TKENIVVNLT IPLKNIA
Length:697
Mass (Da):81,248
Last modified:June 1, 2002 - v1
Checksum:i045C9353A142AE04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590449 Genomic DNA. Translation: CAD25865.1.
RefSeqiNP_586261.1. NM_001042094.1.

Genome annotation databases

GeneIDi859911.
KEGGiecu:ECU10_1460.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590449 Genomic DNA. Translation: CAD25865.1 .
RefSeqi NP_586261.1. NM_001042094.1.

3D structure databases

ProteinModelPortali Q8SR10.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6035.ECU10_1460.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 859911.
KEGGi ecu:ECU10_1460.

Organism-specific databases

EuPathDBi MicrosporidiaDB:ECU10_1460.

Phylogenomic databases

eggNOGi COG0008.
HOGENOMi HOG000259233.
InParanoidi Q8SR10.
KOi K01886.
OMAi RMQKRAK.
OrthoDBi EOG7MD4ZK.

Family and domain databases

Gene3Di 1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR004514. Gln-tRNA-synth.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR10119. PTHR10119. 1 hit.
Pfami PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view ]
PRINTSi PR00987. TRNASYNTHGLU.
SUPFAMi SSF50715. SSF50715. 1 hit.
TIGRFAMsi TIGR00440. glnS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GB-M1.

Entry informationi

Entry nameiSYQ_ENCCU
AccessioniPrimary (citable) accession number: Q8SR10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: June 1, 2002
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3