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Q8SQU8

- YBC9_ENCCU

UniProt

Q8SQU8 - YBC9_ENCCU

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Protein
Probable cell division protein kinase ECU11_1290
Gene
ECU11_1290
Organism
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

May play a role in the control of the eukaryotic cell cycle By similarity.1 Publication

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei42 – 421ATP By similarity
Active sitei138 – 1381Proton acceptor By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 279ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. cyclin-dependent protein serine/threonine kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. mitotic nuclear division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Biological processi

Cell cycle, Cell division, Mitosis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cell division protein kinase ECU11_1290 (EC:2.7.11.22)
Gene namesi
Ordered Locus Names:ECU11_1290
OrganismiEncephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite)
Taxonomic identifieri284813 [NCBI]
Taxonomic lineageiEukaryotaFungiMicrosporidiaUnikaryonidaeEncephalitozoon
ProteomesiUP000000819: Chromosome XI

Organism-specific databases

EuPathDBiMicrosporidiaDB:ECU11_1290.

Subcellular locationi

Nucleus Inferred

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 315315Probable cell division protein kinase ECU11_1290
PRO_0000385506Add
BLAST

Proteomic databases

PRIDEiQ8SQU8.

Interactioni

Protein-protein interaction databases

STRINGi6035.ECU11_1290.

Structurei

3D structure databases

ProteinModelPortaliQ8SQU8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 294282Protein kinase
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
KOiK08818.
OrthoDBiEOG7K3TWD.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8SQU8-1 [UniParc]FASTAAdd to Basket

« Hide

MRSGGRCNSI ENYEKVCRIS SGSFGNVYRV RRKTDNRVFA LKRMNPSMCY    50
DTNGFSILYI REVMILKHIR HRNIMEIEEV VEGCEINDFF IVMECCDTDL 100
RSVIHSVGKI GMKAARFLTC QMLKGLKFLH GAGIVHRDLK PSNILLMRDG 150
GLRIADFGLA RAIESQMTNL VVTLWYRPIE ILLGSETYDE SIDMWSVGCV 200
VGEMLRGEPI LAGEGEMDQL DRIFRLLGYP TDADFEGLDL PHFKNIRRPS 250
TFEASFEGDF ECYGEEAASF VRNLLSFDPR KRCTASQGLC SGFVADAEEC 300
PGELVDIVGR CTGDI 315
Length:315
Mass (Da):35,550
Last modified:May 29, 2013 - v2
Checksum:i6328576685C3E217
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590450 Genomic DNA. Translation: CAD26039.2.
RefSeqiNP_586435.1. NM_001042268.1.

Genome annotation databases

GeneIDi860089.
KEGGiecu:ECU11_1290.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL590450 Genomic DNA. Translation: CAD26039.2 .
RefSeqi NP_586435.1. NM_001042268.1.

3D structure databases

ProteinModelPortali Q8SQU8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6035.ECU11_1290.

Proteomic databases

PRIDEi Q8SQU8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 860089.
KEGGi ecu:ECU11_1290.

Organism-specific databases

EuPathDBi MicrosporidiaDB:ECU11_1290.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
KOi K08818.
OrthoDBi EOG7K3TWD.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GB-M1.
  2. "Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation."
    Peyretaillade E., Goncalves O., Terrat S., Dugat-Bony E., Wincker P., Cornman R.S., Evans J.D., Delbac F., Peyret P.
    BMC Genomics 10:607-607(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: GB-M1.
  3. "The complement of protein kinases of the microsporidium Encephalitozoon cuniculi in relation to those of Saccharomyces cerevisiae and Schizosaccharomyces pombe."
    Miranda-Saavedra D., Stark M.J.R., Packer J.C., Vivares C.P., Doerig C., Barton G.J.
    BMC Genomics 8:309-309(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PREDICTION OF FUNCTION.

Entry informationi

Entry nameiYBC9_ENCCU
AccessioniPrimary (citable) accession number: Q8SQU8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 29, 2013
Last modified: September 3, 2014
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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