ID   ILL1_ORYSJ              Reviewed;         442 AA.
AC   Q8S9S4; B7EYM8;
DT   14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   27-MAR-2024, entry version 123.
DE   RecName: Full=IAA-amino acid hydrolase ILR1-like 1;
DE            EC=3.5.1.-;
DE   Flags: Precursor;
GN   Name=ILL1; Synonyms=IAR;
GN   OrderedLocusNames=Os01g0560000, LOC_Os01g37960;
GN   ORFNames=B1064G04.44, OsJ_002169;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA   Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA   Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA   Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA   Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA   Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA   Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA   Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA   Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA   Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA   Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- FUNCTION: Hydrolyzes certain amino acid conjugates of the plant growth
CC       regulator indole-3-acetic acid (IAA). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen {ECO:0000255|PROSITE-
CC       ProRule:PRU10138}.
CC   -!- SIMILARITY: Belongs to the peptidase M20 family. {ECO:0000305}.
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DR   EMBL; AP003924; BAB85405.1; -; Genomic_DNA.
DR   EMBL; AP008207; BAF05261.1; -; Genomic_DNA.
DR   EMBL; AP014957; BAS72716.1; -; Genomic_DNA.
DR   EMBL; CM000138; EAZ12344.1; -; Genomic_DNA.
DR   EMBL; AK105974; BAG97475.1; -; mRNA.
DR   RefSeq; XP_015621783.1; XM_015766297.1.
DR   AlphaFoldDB; Q8S9S4; -.
DR   SMR; Q8S9S4; -.
DR   STRING; 39947.Q8S9S4; -.
DR   MEROPS; M20.014; -.
DR   PaxDb; 39947-Q8S9S4; -.
DR   EnsemblPlants; Os01t0560000-01; Os01t0560000-01; Os01g0560000.
DR   GeneID; 4324686; -.
DR   Gramene; Os01t0560000-01; Os01t0560000-01; Os01g0560000.
DR   KEGG; osa:4324686; -.
DR   eggNOG; ENOG502QQEM; Eukaryota.
DR   HOGENOM; CLU_023257_0_0_1; -.
DR   InParanoid; Q8S9S4; -.
DR   OMA; VNKGMMH; -.
DR   OrthoDB; 3684955at2759; -.
DR   PlantReactome; R-OSA-1119580; IAA biosynthesis II.
DR   Proteomes; UP000000763; Chromosome 1.
DR   Proteomes; UP000007752; Chromosome 1.
DR   Proteomes; UP000059680; Chromosome 1.
DR   ExpressionAtlas; Q8S9S4; baseline and differential.
DR   GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR   GO; GO:0010179; F:IAA-Ala conjugate hydrolase activity; IBA:GO_Central.
DR   GO; GO:0009850; P:auxin metabolic process; IBA:GO_Central.
DR   CDD; cd08017; M20_IAA_Hyd; 1.
DR   Gene3D; 3.30.70.360; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR017439; Amidohydrolase.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR044757; ILR1-like_Hyd.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   NCBIfam; TIGR01891; amidohydrolases; 1.
DR   PANTHER; PTHR11014:SF119; IAA-AMINO ACID HYDROLASE ILR1-LIKE 1; 1.
DR   PANTHER; PTHR11014; PEPTIDASE M20 FAMILY MEMBER; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF005962; Pept_M20D_amidohydro; 1.
DR   SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00014; ER_TARGET; 1.
DR   Genevisible; Q8S9S4; OS.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Hydrolase; Reference proteome; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..442
FT                   /note="IAA-amino acid hydrolase ILR1-like 1"
FT                   /id="PRO_0000351636"
FT   MOTIF           439..442
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10138"
SQ   SEQUENCE   442 AA;  47135 MW;  CCF19252E3EBF748 CRC64;
     MAAASSSRVL LAAVAVLAAA LAGCGAGAAL DDPAGLLRRA KEAEFAGWMV GLRRRIHENP
     ELGYEEFATS ELVRRELDAL GIPYRHPFAV TGVVATVGTG GPPFVALRAD MDALPMQESV
     EWEHKSKVPG KMHGCGHDAH VAMLLGSARI LQEHRDELKG TVVLVFQPAE EGGGGAKKMI
     DDGAVENIEA IFGVHVADVV PIGVVASRPG PVMAGSGFFE AVISGKGGHA ALPHHTIDPI
     LAASNVIVSL QQLVSREADP LDSQVVTVGK FQGGGAFNVI PDSVTIGGTF RAFLKESFNQ
     LKQRIEEVIV SQASVQRCNA VVDFLDKDRP FFPPTINSAG LHDFFVKVAS EMVGPKNVRD
     KQPLMGAEDF AFYADAIPAT YYYFLGMYNE TRGPQAPHHS PYFTINEDAL PYGAALQASL
     AARYLLEHQP PTTGKAKAHD EL
//