UniProtKB - Q8S920 (UBC5A_ORYSJ)
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Protein
Ubiquitin-conjugating enzyme E2 5A
Gene
UBC5A
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.1 Publication
Catalytic activityi
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotationView all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 85 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ubiquitin-protein transferase activity Source: UniProtKB
GO - Biological processi
- protein ubiquitination Source: UniProtKB
Keywordsi
Molecular function | Transferase |
Biological process | Ubl conjugation pathway |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-OSA-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A. R-OSA-5689896. Ovarian tumor domain proteases. R-OSA-8866652. Synthesis of active ubiquitin: roles of E1 and E2 enzymes. R-OSA-8866654. E3 ubiquitin ligases ubiquitinate target proteins. R-OSA-983168. Antigen processing: Ubiquitination & Proteasome degradation. |
UniPathwayi | UPA00143. |
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquitin-conjugating enzyme E2 5A (EC:2.3.2.23)Alternative name(s): E2 ubiquitin-conjugating enzyme 5A Ubiquitin carrier protein 5a Short name: OsUBC5a Ubiquitin-protein ligase 5A |
Gene namesi | Name:UBC5A Ordered Locus Names:Os01g0658400, LOC_Os01g46926 ORF Names:OsJ_02884 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000397684 | 1 – 147 | Ubiquitin-conjugating enzyme E2 5AAdd BLAST | 147 |
Proteomic databases
PaxDbi | Q8S920. |
PRIDEi | Q8S920. |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8S920. baseline and differential. |
Genevisiblei | Q8S920. OS. |
Structurei
3D structure databases
ProteinModelPortali | Q8S920. |
SMRi | Q8S920. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | KOG0417. Eukaryota. COG5078. LUCA. |
InParanoidi | Q8S920. |
KOi | K06689. |
OMAi | TDRQKYN. |
OrthoDBi | EOG09360PU6. |
Family and domain databases
CDDi | cd00195. UBCc. 1 hit. |
Gene3Di | 3.10.110.10. 1 hit. |
InterProi | View protein in InterPro IPR000608. UBQ-conjugat_E2. IPR023313. UBQ-conjugating_AS. IPR016135. UBQ-conjugating_enzyme/RWD. |
Pfami | View protein in Pfam PF00179. UQ_con. 1 hit. |
SUPFAMi | SSF54495. SSF54495. 1 hit. |
PROSITEi | View protein in PROSITE PS00183. UBIQUITIN_CONJUGAT_1. 1 hit. PS50127. UBIQUITIN_CONJUGAT_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q8S920-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASKRIQKEL KDLQKDPPTS CSAGPVGEDM FHWQATIMGP SDSPYAGGVF
60 70 80 90 100
LVTIHFPPDY PFKPPKVAFR TKVFHPNINS NGSICLDILK DQWSPALTIS
110 120 130 140
KVLLSICSLL TDPNPDDPLV PEIAHMYKTD RHKYENTART WTQRYAM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB074411 mRNA. Translation: BAB89354.1. AP008207 Genomic DNA. Translation: BAF05677.1. AP014957 Genomic DNA. Translation: BAS73515.1. CM000138 Genomic DNA. Translation: EEE55114.1. AK063826 mRNA. Translation: BAG88879.1. AK099284 mRNA. Translation: BAG94041.1. |
RefSeqi | XP_015650522.1. XM_015795036.1. |
UniGenei | Os.8873. |
Genome annotation databases
EnsemblPlantsi | Os01t0658400-01; Os01t0658400-01; Os01g0658400. |
GeneIDi | 4327162. |
Gramenei | Os01t0658400-01; Os01t0658400-01; Os01g0658400. |
KEGGi | osa:4327162. |
Similar proteinsi
Entry informationi
Entry namei | UBC5A_ORYSJ | |
Accessioni | Q8S920Primary (citable) accession number: Q8S920 Secondary accession number(s): A0A0P0V661 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 5, 2010 |
Last sequence update: | June 1, 2002 | |
Last modified: | February 28, 2018 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |