Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ubiquitin-conjugating enzyme E2 5A

Gene

UBC5A

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.1 Publication

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei85 – 851Glycyl thioester intermediatePROSITE-ProRule annotation

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: UniProtKB

GO - Biological processi

  • protein ubiquitination Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Ubl conjugation pathway

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-OSA-179409. APC-Cdc20 mediated degradation of Nek2A.
UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2 5A (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 5A
Ubiquitin carrier protein 5a
Short name:
OsUBC5a
Ubiquitin-protein ligase 5A
Gene namesi
Name:UBC5A
Ordered Locus Names:Os01g0658400, LOC_Os01g46926
ORF Names:OsJ_02884
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 147147Ubiquitin-conjugating enzyme E2 5APRO_0000397684Add
BLAST

Proteomic databases

PaxDbiQ8S920.
PRIDEiQ8S920.

Expressioni

Gene expression databases

ExpressionAtlasiQ8S920. baseline and differential.
GenevisibleiQ8S920. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g46926.1.

Structurei

3D structure databases

ProteinModelPortaliQ8S920.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
InParanoidiQ8S920.
OMAiICCRTTS.
OrthoDBiEOG09360PU6.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8S920-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKRIQKEL KDLQKDPPTS CSAGPVGEDM FHWQATIMGP SDSPYAGGVF
60 70 80 90 100
LVTIHFPPDY PFKPPKVAFR TKVFHPNINS NGSICLDILK DQWSPALTIS
110 120 130 140
KVLLSICSLL TDPNPDDPLV PEIAHMYKTD RHKYENTART WTQRYAM
Length:147
Mass (Da):16,573
Last modified:June 1, 2002 - v1
Checksum:i9FAA726F5C506F09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB074411 mRNA. Translation: BAB89354.1.
AP008207 Genomic DNA. Translation: BAF05677.1.
AP014957 Genomic DNA. Translation: BAS73515.1.
CM000138 Genomic DNA. Translation: EEE55114.1.
AK063826 mRNA. Translation: BAG88879.1.
AK099284 mRNA. Translation: BAG94041.1.
RefSeqiXP_015650522.1. XM_015795036.1.
UniGeneiOs.8873.

Genome annotation databases

EnsemblPlantsiOS01T0658400-01; OS01T0658400-01; OS01G0658400.
GeneIDi4327162.
GrameneiOS01T0658400-01; OS01T0658400-01; OS01G0658400.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB074411 mRNA. Translation: BAB89354.1.
AP008207 Genomic DNA. Translation: BAF05677.1.
AP014957 Genomic DNA. Translation: BAS73515.1.
CM000138 Genomic DNA. Translation: EEE55114.1.
AK063826 mRNA. Translation: BAG88879.1.
AK099284 mRNA. Translation: BAG94041.1.
RefSeqiXP_015650522.1. XM_015795036.1.
UniGeneiOs.8873.

3D structure databases

ProteinModelPortaliQ8S920.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g46926.1.

Proteomic databases

PaxDbiQ8S920.
PRIDEiQ8S920.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0658400-01; OS01T0658400-01; OS01G0658400.
GeneIDi4327162.
GrameneiOS01T0658400-01; OS01T0658400-01; OS01G0658400.

Phylogenomic databases

eggNOGiKOG0417. Eukaryota.
COG5078. LUCA.
InParanoidiQ8S920.
OMAiICCRTTS.
OrthoDBiEOG09360PU6.

Enzyme and pathway databases

UniPathwayiUPA00143.
ReactomeiR-OSA-174184. Cdc20:Phospho-APC/C mediated degradation of Cyclin A.
R-OSA-179409. APC-Cdc20 mediated degradation of Nek2A.

Gene expression databases

ExpressionAtlasiQ8S920. baseline and differential.
GenevisibleiQ8S920. OS.

Family and domain databases

Gene3Di3.10.110.10. 1 hit.
InterProiIPR000608. UBQ-conjugat_E2.
IPR023313. UBQ-conjugating_AS.
IPR016135. UBQ-conjugating_enzyme/RWD.
[Graphical view]
PfamiPF00179. UQ_con. 1 hit.
[Graphical view]
SUPFAMiSSF54495. SSF54495. 1 hit.
PROSITEiPS00183. UBIQUITIN_CONJUGAT_1. 1 hit.
PS50127. UBIQUITIN_CONJUGAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUBC5A_ORYSJ
AccessioniPrimary (citable) accession number: Q8S920
Secondary accession number(s): A0A0P0V661
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: June 1, 2002
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.