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Protein

Ubiquitin-conjugating enzyme E2 5B

Gene

UBC5B

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

E2 conjugating enzyme that associates with the E3 ubiquitin-protein ligase EL5 to mediates ubiquitination of target proteins.1 Publication

Catalytic activityi

S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei85Glycyl thioester intermediatePROSITE-ProRule annotation1

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • ubiquitin-protein transferase activity Source: UniProtKB

GO - Biological processi

  • protein ubiquitination Source: UniProtKB
  • ubiquitin-dependent protein catabolic process Source: EnsemblPlants

Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi6.3.2.19 4460
ReactomeiR-OSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-OSA-5689896 Ovarian tumor domain proteases
R-OSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes
R-OSA-9033241 Peroxisomal protein import
R-OSA-983168 Antigen processing: Ubiquitination & Proteasome degradation
UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-conjugating enzyme E2 5B (EC:2.3.2.23)
Alternative name(s):
E2 ubiquitin-conjugating enzyme 5B
Ubiquitin carrier protein 5b
Short name:
OsUBC5b
Ubiquitin-protein ligase 5B
Gene namesi
Name:UBC5B
Ordered Locus Names:Os02g0261100, LOC_Os02g16040
ORF Names:OsJ_06152, OSJNBb0026F09.5
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003976851 – 148Ubiquitin-conjugating enzyme E2 5BAdd BLAST148

Proteomic databases

PaxDbiQ8S919
PRIDEiQ8S919

Expressioni

Inductioni

By N-acetylchitooligosaccharide elicitor.1 Publication

Gene expression databases

ExpressionAtlasiQ8S919 differential
GenevisibleiQ8S919 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os02g16040.1

Structurei

3D structure databases

ProteinModelPortaliQ8S919
SMRiQ8S919
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0417 Eukaryota
COG5078 LUCA
InParanoidiQ8S919
OMAiNDLGRDP
OrthoDBiEOG09360PU6

Family and domain databases

CDDicd00195 UBCc, 1 hit
Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR000608 UBQ-conjugat_E2
IPR023313 UBQ-conjugating_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF00179 UQ_con, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit
PROSITEiView protein in PROSITE
PS00183 UBIQUITIN_CONJUGAT_1, 1 hit
PS50127 UBIQUITIN_CONJUGAT_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q8S919-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASKRILKEL KDLQKDPPTS CSAGPVAEDM FHWQATLMGP SDSPYAGGVF
60 70 80 90 100
LVTIHFPPDY PFKPPKVALK TKVFHPNINS NGSICLDILK EQWSPALTIS
110 120 130 140
KVLLSICSLL TDPNPDDPLV PEIAHMYKTD RAKYESTARS WTQKYAMG
Length:148
Mass (Da):16,446
Last modified:June 1, 2002 - v1
Checksum:i8BD25EF09F70D1DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB074412 mRNA Translation: BAB89355.1
AP005777 Genomic DNA Translation: BAD20047.1
AP008208 Genomic DNA Translation: BAF08400.1
AP014958 Genomic DNA Translation: BAS77989.1
CM000139 Genomic DNA Translation: EAZ22486.1
AK121248 mRNA Translation: BAH00395.1
RefSeqiXP_015627363.1, XM_015771877.1
UniGeneiOs.7899

Genome annotation databases

EnsemblPlantsiOs02t0261100-01; Os02t0261100-01; Os02g0261100
GeneIDi4328940
GrameneiOs02t0261100-01; Os02t0261100-01; Os02g0261100
KEGGiosa:4328940

Similar proteinsi

Entry informationi

Entry nameiUBC5B_ORYSJ
AccessioniPrimary (citable) accession number: Q8S919
Secondary accession number(s): A0A0P0VHC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 5, 2010
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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