Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q8S8Q4 (GUN14_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 14

EC=3.2.1.4
Alternative name(s):
Endo-1,4-beta glucanase 14
Gene names
Ordered Locus Names:At2g44560
ORF Names:F16B22.5, F4I1.39
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length491 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 9 (cellulase E) family.

Sequence caution

The sequence AAM14961.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cell wall biogenesis/degradation
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential
Chain32 – 491460Endoglucanase 14
PRO_0000249266

Sites

Active site4131 By similarity
Active site4651 By similarity
Active site4741 By similarity

Amino acid modifications

Glycosylation3971N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q8S8Q4 [UniParc].

Last modified September 5, 2006. Version 2.
Checksum: 7F9250C761AA8484

FASTA49153,198
        10         20         30         40         50         60 
MSQLKIGSSQ CLWTSICIVL FVLSMARGAV SRNYGDALTK SLLYFEAQRS GKLPSNQRVT 

        70         80         90        100        110        120 
WRGDSALRDG SDAHVDLTGG YYDAGDNMKF GFPLAFFTTM LAWSNIEMAT QLKAHQEQEN 

       130        140        150        160        170        180 
ALAALKWATD FLIKAHPEPN VLYGQVGDGN SDHECWMRPE DMTTPRPSFR IDAQHPGSDL 

       190        200        210        220        230        240 
AGETAAAMAA ASIAFAPSDE AYAQILIGHA KELFEFAKAY PGIYQNSITN AGGFYASSGY 

       250        260        270        280        290        300 
EDELLWAAAW LHRATNDQIY LDYLTQASGT GGPRTAFSWD DKFVGAQVLV AKLALEGKVE 

       310        320        330        340        350        360 
SNGKIAEYKS MAEQFICNCA QKGSNNVKKT PGGLLYFLPW NNLQYTTAAT FVLSAYSKYL 

       370        380        390        400        410        420 
TDAKASIQCP NGALQASDLL DLARSQVDYI LGSNPQNMSY MVGVGTNYPK KPHHRAASIV 

       430        440        450        460        470        480 
SITKDKTPVT CSEGFDAWFN NPAPNPNVLM GAVVGGPNDN DVYGDERTDY QHAEPAPATA 

       490 
APFVGVLAAV A 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
Libertini E., Li Y., McQueen-Mason S.J.
J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC003672 Genomic DNA. Translation: AAC27458.1.
AC004521 Genomic DNA. Translation: AAM14961.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC10438.1.
AK175889 mRNA. Translation: BAD43652.1.
PIRT01583.
RefSeqNP_181984.1. NM_130020.2.
UniGeneAt.36743.

3D structure databases

ProteinModelPortalQ8S8Q4.
SMRQ8S8Q4. Positions 33-490.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH9. Glycoside Hydrolase Family 9.

Proteomic databases

PaxDbQ8S8Q4.
PRIDEQ8S8Q4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G44560.1; AT2G44560.1; AT2G44560.
GeneID819064.
KEGGath:AT2G44560.

Organism-specific databases

TAIRAT2G44560.

Phylogenomic databases

eggNOGNOG05134.
HOGENOMHOG000021033.
InParanoidQ8S8Q4.
OMAANPERMS.
PhylomeDBQ8S8Q4.

Enzyme and pathway databases

BioCycARA:AT2G44560-MONOMER.

Gene expression databases

GenevestigatorQ8S8Q4.

Family and domain databases

Gene3D1.50.10.10. 1 hit.
InterProIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMSSF48208. SSF48208. 1 hit.
PROSITEPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN14_ARATH
AccessionPrimary (citable) accession number: Q8S8Q4
Secondary accession number(s): O64891
Entry history
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: May 14, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names