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Protein

Endoglucanase 14

Gene

At2g44560

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei413 – 4131PROSITE-ProRule annotation
Active sitei465 – 4651PROSITE-ProRule annotation
Active sitei474 – 4741PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cell wall biogenesis/degradation, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

BioCyciARA:AT2G44560-MONOMER.

Protein family/group databases

CAZyiGH9. Glycoside Hydrolase Family 9.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase 14 (EC:3.2.1.4)
Alternative name(s):
Endo-1,4-beta glucanase 14
Gene namesi
Ordered Locus Names:At2g44560
ORF Names:F16B22.5, F4I1.39
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G44560.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3131Sequence AnalysisAdd
BLAST
Chaini32 – 491460Endoglucanase 14PRO_0000249266Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi397 – 3971N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8S8Q4.
PRIDEiQ8S8Q4.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G44560.1.

Structurei

3D structure databases

ProteinModelPortaliQ8S8Q4.
SMRiQ8S8Q4. Positions 33-490.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG05134.
HOGENOMiHOG000021033.
InParanoidiQ8S8Q4.
OMAiGKVESNG.
PhylomeDBiQ8S8Q4.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamiPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8S8Q4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQLKIGSSQ CLWTSICIVL FVLSMARGAV SRNYGDALTK SLLYFEAQRS
60 70 80 90 100
GKLPSNQRVT WRGDSALRDG SDAHVDLTGG YYDAGDNMKF GFPLAFFTTM
110 120 130 140 150
LAWSNIEMAT QLKAHQEQEN ALAALKWATD FLIKAHPEPN VLYGQVGDGN
160 170 180 190 200
SDHECWMRPE DMTTPRPSFR IDAQHPGSDL AGETAAAMAA ASIAFAPSDE
210 220 230 240 250
AYAQILIGHA KELFEFAKAY PGIYQNSITN AGGFYASSGY EDELLWAAAW
260 270 280 290 300
LHRATNDQIY LDYLTQASGT GGPRTAFSWD DKFVGAQVLV AKLALEGKVE
310 320 330 340 350
SNGKIAEYKS MAEQFICNCA QKGSNNVKKT PGGLLYFLPW NNLQYTTAAT
360 370 380 390 400
FVLSAYSKYL TDAKASIQCP NGALQASDLL DLARSQVDYI LGSNPQNMSY
410 420 430 440 450
MVGVGTNYPK KPHHRAASIV SITKDKTPVT CSEGFDAWFN NPAPNPNVLM
460 470 480 490
GAVVGGPNDN DVYGDERTDY QHAEPAPATA APFVGVLAAV A
Length:491
Mass (Da):53,198
Last modified:September 5, 2006 - v2
Checksum:i7F9250C761AA8484
GO

Sequence cautioni

The sequence AAM14961.1 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003672 Genomic DNA. Translation: AAC27458.1.
AC004521 Genomic DNA. Translation: AAM14961.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC10438.1.
AK175889 mRNA. Translation: BAD43652.1.
PIRiT01583.
RefSeqiNP_181984.1. NM_130020.2.
UniGeneiAt.36743.

Genome annotation databases

EnsemblPlantsiAT2G44560.1; AT2G44560.1; AT2G44560.
GeneIDi819064.
KEGGiath:AT2G44560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003672 Genomic DNA. Translation: AAC27458.1.
AC004521 Genomic DNA. Translation: AAM14961.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC10438.1.
AK175889 mRNA. Translation: BAD43652.1.
PIRiT01583.
RefSeqiNP_181984.1. NM_130020.2.
UniGeneiAt.36743.

3D structure databases

ProteinModelPortaliQ8S8Q4.
SMRiQ8S8Q4. Positions 33-490.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G44560.1.

Protein family/group databases

CAZyiGH9. Glycoside Hydrolase Family 9.

Proteomic databases

PaxDbiQ8S8Q4.
PRIDEiQ8S8Q4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G44560.1; AT2G44560.1; AT2G44560.
GeneIDi819064.
KEGGiath:AT2G44560.

Organism-specific databases

TAIRiAT2G44560.

Phylogenomic databases

eggNOGiNOG05134.
HOGENOMiHOG000021033.
InParanoidiQ8S8Q4.
OMAiGKVESNG.
PhylomeDBiQ8S8Q4.

Enzyme and pathway databases

BioCyciARA:AT2G44560-MONOMER.

Miscellaneous databases

PROiQ8S8Q4.

Family and domain databases

Gene3Di1.50.10.10. 1 hit.
InterProiIPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR001701. Glyco_hydro_9.
IPR018221. Glyco_hydro_9_AS.
[Graphical view]
PfamiPF00759. Glyco_hydro_9. 1 hit.
[Graphical view]
SUPFAMiSSF48208. SSF48208. 1 hit.
PROSITEiPS00592. GLYCOSYL_HYDROL_F9_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
    Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.
    , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
    Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Phylogenetic analysis of the plant endo-beta-1,4-glucanase gene family."
    Libertini E., Li Y., McQueen-Mason S.J.
    J. Mol. Evol. 58:506-515(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY.

Entry informationi

Entry nameiGUN14_ARATH
AccessioniPrimary (citable) accession number: Q8S8Q4
Secondary accession number(s): O64891
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: September 5, 2006
Last modified: July 22, 2015
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.