Q8S3N2 (DCOR_CAPAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ornithine decarboxylase
Short name=ODC
EC=4.1.1.17

Alternative name(s):
CaODC1
CapODC

Gene names

Name:	ODC
Synonyms:	CUKM10

Organism

Capsicum annuum (Bell pepper)

Taxonomic identifier

4072 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Capsiceae › Capsicum

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	L-ornithine = putrescine + CO2.
Cofactor	Pyridoxal phosphate.
Pathway	Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.
Induction	By virus infection. Up-regulated during the later stages of ripening. Ref.1 Ref.2
Sequence similarities	Belongs to the Orn/Lys/Arg decarboxylase class-II family.

Ontologies

Keywords
Biological process	Polyamine biosynthesis
Ligand	Pyridoxal phosphate
Molecular function	Decarboxylase Lyase
Gene Ontology (GO)
Biological process	polyamine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ornithine decarboxylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 435	435	Ornithine decarboxylase		PRO_0000239254
Sites
	Active site	380	1	Proton donor; shared with dimeric partner By similarity
Amino acid modifications
	Modified residue	98	1	N6-(pyridoxal phosphate)lysine By similarity
Experimental info
	Sequence conflict	65	1	E → K in AAL83709. Ref.2
	Sequence conflict	92	1	R → H in AAL83709. Ref.2
	Sequence conflict	117	1	V → D in AAL83709. Ref.2
	Sequence conflict	391 – 392	2	HV → QL in AAL83709. Ref.2
	Sequence conflict	401	1	V → L in AAL83709. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q8S3N2 [UniParc]. Last modified June 1, 2002. Version 1. Checksum: CC38830BFD7B1B76	FASTA	435	46,906
	10 20 30 40 50 60 MAGQTVIVSG LNPAAILQST IGGAPPSTAA AAAENGDTTR KVVPLSKDAL QDFMVSIITQ 70 80 90 100 110 120 KLQGEKKPFY VLDLGEVVSL MDQWNVALPN VRPFYAVKCN PEPSFLSMLA AMGSNFVCAS 130 140 150 160 170 180 RAEIEYVLSL GISPERIVFA NPCKPESDII FAEKVGVNLT TYDSEDEVYK IKKHHPKCEL 190 200 210 220 230 240 LLRIKPMNDG NARCPMGPKY GALPEEIEPL LRIAQASRLT VSGVSFHIGS GDADSNAYLG 250 260 270 280 290 300 AIAAAKQVFE TAAKFGMSKM NVLDIGGGFT SGHQFTTAAT AVKSALQQHF SNEPELTIIA 310 320 330 340 350 360 EPGRFFAETA FTLATTIIGK RVRGDLREYW INDGLYGSMN CVLYDHATVT ATPLACMSNR 370 380 390 400 410 420 VNLNCSGSKM FPSTIFGPTC DALDTVLRDY HVPELQVNDW VIFPNMGAYT KAAGSNFNGF 430 NTSAIVTHLA YAYPS

References

[1]	"Molecular cloning and sequence analysis of a cDNA encoding ornithine decarboxylase cDNA from chilli (Capsicum annuum)." Zainal Z., Sajari R., Ismail I. J. Biochem. Mol. Biol. Biophys. 6:415-419(2002) [PubMed: 14972797] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION. Strain: cv. MC11. Tissue: Fruit.
[2]	"A hot pepper cDNA encoding ornithine decarboxylase is induced during the resistance response to tobacco mosaic virus." Yoo T.H., Park C.-J., Lee G.-J., Shin R., Kim K.-J., Yun J.-H., Paek K.-H. Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA], INDUCTION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF480882 mRNA. Translation: AAL87201.1. AY078081 mRNA. Translation: AAL83709.1.
3D structure databases
ProteinModelPortal	Q8S3N2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-14989.
Family and domain databases
InterPro	IPR009006. Ala_racemase/Decarboxylase_C. IPR022643. De-COase2_C. IPR022657. De-COase2_CS. IPR022644. De-COase2_N. IPR022653. De-COase2_pyr-phos_BS. IPR000183. Orn/DAP/Arg_de-COase. IPR002433. Orn_de-COase. [Graphical view]
Gene3D	G3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
Pfam	PF02784. Orn_Arg_deC_N. 1 hit. PF00278. Orn_DAP_Arg_deC. 1 hit. [Graphical view]
PRINTS	PR01179. ODADCRBXLASE. PR01182. ORNDCRBXLASE.
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
PROSITE	PS00878. ODR_DC_2_1. 1 hit. PS00879. ODR_DC_2_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DCOR_CAPAN

Accession

Primary (citable) accession number: Q8S3N2
Secondary accession number(s): Q84UH2

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2006
Last sequence update:	June 1, 2002
Last modified:	September 21, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program