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Q8S341 (PPA7_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purple acid phosphatase 7

EC=3.1.3.2
Gene names
Name:PAP7
Ordered Locus Names:At2g01880
ORF Names:T23K3.7
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

A phosphate monoester + H2O = an alcohol + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 zinc ion per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Secreted By similarity.

Tissue specificity

Expressed in roots, stems, leaves, flowers and siliques. Ref.6

Sequence similarities

Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.

Sequence caution

The sequence AAD21780.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   LigandIron
Metal-binding
Zinc
   Molecular functionHydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from sequence or structural similarity Ref.1Ref.6. Source: GOC

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacid phosphatase activity

Inferred from sequence or structural similarity Ref.1Ref.6. Source: TAIR

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 328304Purple acid phosphatase 7
PRO_0000372812

Regions

Region248 – 2503Substrate binding By similarity

Sites

Active site2221Proton donor By similarity
Metal binding481Iron By similarity
Metal binding811Iron By similarity
Metal binding811Zinc By similarity
Metal binding841Iron By similarity
Metal binding1191Zinc By similarity
Metal binding2131Zinc By similarity
Metal binding2481Zinc By similarity
Metal binding2501Iron By similarity

Amino acid modifications

Glycosylation561N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict3171H → L in BAC43423. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q8S341 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: F897E0A8D39CA052

FASTA32837,549
        10         20         30         40         50         60 
MKMHVCFSVI LMFLSIFFIN GALSKLERLK HPVKKKSDGS LSFLVIGDWG RKGGFNQSLV 

        70         80         90        100        110        120 
AHQMGVVGEK LDIDFVISVG DNFYDDGLKG VNDPSFEASF SHIYTHPSLQ KQWYSVLGNH 

       130        140        150        160        170        180 
DYRGNVEAQL SKVLTQKDWR WFCRRSFVLS SGMVDFFFAD TNPFVEKYFT EPEDHTYDWR 

       190        200        210        220        230        240 
NVLPRNKYIS NLLHDLDLEI KKSRATWKFV VGHHGIKTAG NHGVTQELVD QLLPILEENK 

       250        260        270        280        290        300 
VDLYINGHDH CLQHIGSHGK TQFLTSGGGS KAWRGHVQPW DPKELKLYYD GQGFMSLHIT 

       310        320 
HSKAKFIYYD VSGNVLHRSS LSKRSAHL 

« Hide

References

« Hide 'large scale' references
[1]"Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
Strain: cv. Col-1.
[2]"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A. expand/collapse author list , Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.
Nature 402:761-768(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[3]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[4]"Functional annotation of a full-length Arabidopsis cDNA collection."
Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K., Shinagawa A., Shinozaki K.
Science 296:141-145(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Arabidopsis ORF Clones."
Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.
Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[6]"Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF492659 mRNA. Translation: AAM15908.1.
AC007069 Genomic DNA. Translation: AAD21780.1. Sequence problems.
CP002685 Genomic DNA. Translation: AEC05511.1.
AK118834 mRNA. Translation: BAC43423.1.
BT026449 mRNA. Translation: ABH04556.1.
PIRC84430.
RefSeqNP_178297.2. NM_126249.4.
UniGeneAt.42460.

3D structure databases

ProteinModelPortalQ8S341.
SMRQ8S341. Positions 41-325.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT2G01880.1-P.

Proteomic databases

PaxDbQ8S341.
PRIDEQ8S341.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT2G01880.1; AT2G01880.1; AT2G01880.
GeneID814719.
KEGGath:AT2G01880.

Organism-specific databases

TAIRAT2G01880.

Phylogenomic databases

eggNOGCOG1409.
HOGENOMHOG000239892.
InParanoidQ8S341.
OMAINGHEHN.
PhylomeDBQ8S341.
ProtClustDBCLSN2688499.

Enzyme and pathway databases

BioCycARA:AT2G01880-MONOMER.

Gene expression databases

GenevestigatorQ8S341.

Family and domain databases

InterProIPR024927. Acid_Pase_5.
IPR004843. Calcineurin-like_PHP_apaH.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PIRSFPIRSF000898. Acid_Ptase_5. 1 hit.
ProtoNetSearch...

Entry information

Entry namePPA7_ARATH
AccessionPrimary (citable) accession number: Q8S341
Secondary accession number(s): Q8GWH8, Q9SIS6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: June 1, 2002
Last modified: April 16, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names