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Q8S341

- PPA7_ARATH

UniProt

Q8S341 - PPA7_ARATH

Protein

Purple acid phosphatase 7

Gene

PAP7

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Jun 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    A phosphate monoester + H2O = an alcohol + phosphate.

    Cofactori

    Binds 1 iron ion per subunit.By similarity
    Binds 1 zinc ion per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi48 – 481IronBy similarity
    Metal bindingi81 – 811IronBy similarity
    Metal bindingi81 – 811ZincBy similarity
    Metal bindingi84 – 841IronBy similarity
    Metal bindingi119 – 1191ZincBy similarity
    Metal bindingi213 – 2131ZincBy similarity
    Active sitei222 – 2221Proton donorBy similarity
    Metal bindingi248 – 2481ZincBy similarity
    Metal bindingi250 – 2501IronBy similarity

    GO - Molecular functioni

    1. acid phosphatase activity Source: TAIR
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. dephosphorylation Source: GOC

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Ligandi

    Iron, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciARA:AT2G01880-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Purple acid phosphatase 7 (EC:3.1.3.2)
    Gene namesi
    Name:PAP7
    Ordered Locus Names:At2g01880
    ORF Names:T23K3.7
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 2

    Organism-specific databases

    TAIRiAT2G01880.

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2424Sequence AnalysisAdd
    BLAST
    Chaini25 – 328304Purple acid phosphatase 7PRO_0000372812Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi56 – 561N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Proteomic databases

    PaxDbiQ8S341.
    PRIDEiQ8S341.

    Expressioni

    Tissue specificityi

    Expressed in roots, stems, leaves, flowers and siliques.1 Publication

    Gene expression databases

    GenevestigatoriQ8S341.

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi3702.AT2G01880.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8S341.
    SMRiQ8S341. Positions 41-325.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni248 – 2503Substrate bindingBy similarity

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG1409.
    HOGENOMiHOG000239892.
    InParanoidiQ8S341.
    OMAiVEKYFTE.
    PhylomeDBiQ8S341.

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR024927. Acid_Pase_5.
    IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000898. Acid_Ptase_5. 1 hit.
    SUPFAMiSSF56300. SSF56300. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q8S341-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKMHVCFSVI LMFLSIFFIN GALSKLERLK HPVKKKSDGS LSFLVIGDWG    50
    RKGGFNQSLV AHQMGVVGEK LDIDFVISVG DNFYDDGLKG VNDPSFEASF 100
    SHIYTHPSLQ KQWYSVLGNH DYRGNVEAQL SKVLTQKDWR WFCRRSFVLS 150
    SGMVDFFFAD TNPFVEKYFT EPEDHTYDWR NVLPRNKYIS NLLHDLDLEI 200
    KKSRATWKFV VGHHGIKTAG NHGVTQELVD QLLPILEENK VDLYINGHDH 250
    CLQHIGSHGK TQFLTSGGGS KAWRGHVQPW DPKELKLYYD GQGFMSLHIT 300
    HSKAKFIYYD VSGNVLHRSS LSKRSAHL 328
    Length:328
    Mass (Da):37,549
    Last modified:June 1, 2002 - v1
    Checksum:iF897E0A8D39CA052
    GO

    Sequence cautioni

    The sequence AAD21780.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti317 – 3171H → L in BAC43423. (PubMed:11910074)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF492659 mRNA. Translation: AAM15908.1.
    AC007069 Genomic DNA. Translation: AAD21780.1. Sequence problems.
    CP002685 Genomic DNA. Translation: AEC05511.1.
    AK118834 mRNA. Translation: BAC43423.1.
    BT026449 mRNA. Translation: ABH04556.1.
    PIRiC84430.
    RefSeqiNP_178297.2. NM_126249.4.
    UniGeneiAt.42460.

    Genome annotation databases

    EnsemblPlantsiAT2G01880.1; AT2G01880.1; AT2G01880.
    GeneIDi814719.
    KEGGiath:AT2G01880.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF492659 mRNA. Translation: AAM15908.1 .
    AC007069 Genomic DNA. Translation: AAD21780.1 . Sequence problems.
    CP002685 Genomic DNA. Translation: AEC05511.1 .
    AK118834 mRNA. Translation: BAC43423.1 .
    BT026449 mRNA. Translation: ABH04556.1 .
    PIRi C84430.
    RefSeqi NP_178297.2. NM_126249.4.
    UniGenei At.42460.

    3D structure databases

    ProteinModelPortali Q8S341.
    SMRi Q8S341. Positions 41-325.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT2G01880.1-P.

    Proteomic databases

    PaxDbi Q8S341.
    PRIDEi Q8S341.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT2G01880.1 ; AT2G01880.1 ; AT2G01880 .
    GeneIDi 814719.
    KEGGi ath:AT2G01880.

    Organism-specific databases

    TAIRi AT2G01880.

    Phylogenomic databases

    eggNOGi COG1409.
    HOGENOMi HOG000239892.
    InParanoidi Q8S341.
    OMAi VEKYFTE.
    PhylomeDBi Q8S341.

    Enzyme and pathway databases

    BioCyci ARA:AT2G01880-MONOMER.

    Gene expression databases

    Genevestigatori Q8S341.

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR024927. Acid_Pase_5.
    IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000898. Acid_Ptase_5. 1 hit.
    SUPFAMi SSF56300. SSF56300. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation."
      Li D., Zhu H., Liu K., Liu X., Leggewie G., Udvardi M., Wang D.
      J. Biol. Chem. 277:27772-27781(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, NOMENCLATURE.
      Strain: cv. Col-1.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    3. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    5. "Arabidopsis ORF Clones."
      Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.
      Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    6. "Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower."
      Zhu H., Qian W., Lu X., Li D., Liu X., Liu K., Wang D.
      Plant Mol. Biol. 59:581-594(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiPPA7_ARATH
    AccessioniPrimary (citable) accession number: Q8S341
    Secondary accession number(s): Q8GWH8, Q9SIS6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 5, 2009
    Last sequence update: June 1, 2002
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3