Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolic

Gene

Os01g0801600

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

May be involved in cell redox homeostasis.By similarity

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei195 – 1951NAD; via amide nitrogenBy similarity
Binding sitei195 – 1951SubstrateBy similarity
Binding sitei234 – 2341NAD; via amide nitrogenBy similarity
Active sitei284 – 2841Proton acceptorBy similarity
Binding sitei346 – 3461NADBy similarity
Binding sitei374 – 3741NADBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi47 – 526NADBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolic (EC:1.1.1.8)
Gene namesi
Ordered Locus Names:Os01g0801600, LOC_Os01g58740
ORF Names:OsJ_03778, P0003D09.23
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
ProteomesiUP000000763 Componenti: Chromosome 1

Organism-specific databases

GrameneiQ8S2G5.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolicPRO_0000420178Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g58740.1.

Structurei

3D structure databases

ProteinModelPortaliQ8S2G5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni346 – 3472Substrate bindingBy similarity

Sequence similaritiesi

Phylogenomic databases

InParanoidiQ8S2G5.
KOiK00006.
OMAiTDTREVF.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8S2G5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGAEDAPRA AAANGHGNGA TVEEKLDELR RLLGKADGDP LRIVGVGAGA
60 70 80 90 100
WGSVFCALMQ DAYGHLRDKV QVRIWRRPGR AVDRATAEHL FEVINAREDV
110 120 130 140 150
LRRLIRRCAY LKYVEGRLGD RTLYADEILR DGFCLNMIDT PLCPLKVVTN
160 170 180 190 200
LQEAVWDADI VINGLPSTDT REVFGEIGRY WKERITAPII LSLAKGIEAS
210 220 230 240 250
LDPLPRIITP TQMISNATGV PLENILYLGG PNIASEIYNK EYANARICGA
260 270 280 290 300
DKWRKPLAKF LRQPHFIVWD NSDLITHEVM GGLKNVYAIG AGMVAALTNE
310 320 330 340 350
SATSKSVYFA LCTSEMIYIT HLLEEEPEKL AGPLLADTYV TLLKGRNAWY
360 370 380 390 400
GQKLAKGELT LEMGDSIKGK GTIQGVSAVN AFYELLSQDS LSVMHPEANR
410 420 430 440 450
SVAPVEMCPI LKALYKILIK RELPPDSILQ AIRDETMYDP RERIEMAQGH
460
SLYRPSLLGQ PKGDAKA
Length:467
Mass (Da):51,583
Last modified:June 1, 2002 - v1
Checksum:i7857AB03C7E6B051
GO

Sequence cautioni

The sequence AAO72676.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti163 – 1653NGL → KRV in AAO72676 (PubMed:14750518).Curated
Sequence conflicti394 – 3941M → V in AK073318 (PubMed:12869764).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003221 Genomic DNA. Translation: BAB86423.1.
AP008207 Genomic DNA. Translation: BAF06455.1.
CM000138 Genomic DNA. Translation: EAZ13855.1.
AK073318 mRNA. No translation available.
AY224556 mRNA. Translation: AAO72676.1. Different initiation.
RefSeqiNP_001044541.1. NM_001051076.1.
UniGeneiOs.88558.

Genome annotation databases

EnsemblPlantsiOS01T0801600-01; OS01T0801600-01; OS01G0801600.
GeneIDi4327964.
KEGGiosa:4327964.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003221 Genomic DNA. Translation: BAB86423.1.
AP008207 Genomic DNA. Translation: BAF06455.1.
CM000138 Genomic DNA. Translation: EAZ13855.1.
AK073318 mRNA. No translation available.
AY224556 mRNA. Translation: AAO72676.1. Different initiation.
RefSeqiNP_001044541.1. NM_001051076.1.
UniGeneiOs.88558.

3D structure databases

ProteinModelPortaliQ8S2G5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g58740.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0801600-01; OS01T0801600-01; OS01G0801600.
GeneIDi4327964.
KEGGiosa:4327964.

Organism-specific databases

GrameneiQ8S2G5.

Phylogenomic databases

InParanoidiQ8S2G5.
KOiK00006.
OMAiTDTREVF.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR008927. 6-PGluconate_DH_C-like.
IPR013328. 6PGD_dom_2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11728. PTHR11728. 1 hit.
PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence and structure of rice chromosome 1."
    Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.
    , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
    Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  5. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  6. "Identification of rice (Oryza sativa) proteins linked to the cyclin-mediated regulation of the cell cycle."
    Cooper B., Hutchison D., Park S., Guimil S., Luginbuehl P., Ellero C., Goff S.A., Glazebrook J.
    Plant Mol. Biol. 53:273-279(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-242.

Entry informationi

Entry nameiGPDH2_ORYSJ
AccessioniPrimary (citable) accession number: Q8S2G5
Secondary accession number(s): Q84VD0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2012
Last sequence update: June 1, 2002
Last modified: July 22, 2015
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.