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Q8S2G5 (GPDH2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolic
EC=1.1.1.8
Gene names
Ordered Locus Names:Os01g0801600, LOC_Os01g58740
ORF Names:OsJ_03778, P0003D09.23
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length467 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May be involved in cell redox homeostasis By similarity.

Catalytic activity

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Subcellular location

Cytoplasm › cytosol By similarity.

Sequence similarities

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

Sequence caution

The sequence AAO72676.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 467467Probable glycerol-3-phosphate dehydrogenase [NAD(+)] 2, cytosolic
PRO_0000420178

Regions

Nucleotide binding47 – 526NAD By similarity
Region346 – 3472Substrate binding By similarity

Sites

Active site2841Proton acceptor By similarity
Binding site1951NAD; via amide nitrogen By similarity
Binding site1951Substrate By similarity
Binding site2341NAD; via amide nitrogen By similarity
Binding site3461NAD By similarity
Binding site3741NAD By similarity

Experimental info

Sequence conflict163 – 1653NGL → KRV in AAO72676. Ref.6
Sequence conflict3941M → V in AK073318. Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q8S2G5 [UniParc].

Last modified June 1, 2002. Version 1.
Checksum: 7857AB03C7E6B051

FASTA46751,583
        10         20         30         40         50         60 
MGGAEDAPRA AAANGHGNGA TVEEKLDELR RLLGKADGDP LRIVGVGAGA WGSVFCALMQ 

        70         80         90        100        110        120 
DAYGHLRDKV QVRIWRRPGR AVDRATAEHL FEVINAREDV LRRLIRRCAY LKYVEGRLGD 

       130        140        150        160        170        180 
RTLYADEILR DGFCLNMIDT PLCPLKVVTN LQEAVWDADI VINGLPSTDT REVFGEIGRY 

       190        200        210        220        230        240 
WKERITAPII LSLAKGIEAS LDPLPRIITP TQMISNATGV PLENILYLGG PNIASEIYNK 

       250        260        270        280        290        300 
EYANARICGA DKWRKPLAKF LRQPHFIVWD NSDLITHEVM GGLKNVYAIG AGMVAALTNE 

       310        320        330        340        350        360 
SATSKSVYFA LCTSEMIYIT HLLEEEPEKL AGPLLADTYV TLLKGRNAWY GQKLAKGELT 

       370        380        390        400        410        420 
LEMGDSIKGK GTIQGVSAVN AFYELLSQDS LSVMHPEANR SVAPVEMCPI LKALYKILIK 

       430        440        450        460 
RELPPDSILQ AIRDETMYDP RERIEMAQGH SLYRPSLLGQ PKGDAKA

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[2]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[4]"The genomes of Oryza sativa: a history of duplications."
Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L. expand/collapse author list , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[5]"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
The rice full-length cDNA consortium
Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Nipponbare.
[6]"Identification of rice (Oryza sativa) proteins linked to the cyclin-mediated regulation of the cell cycle."
Cooper B., Hutchison D., Park S., Guimil S., Luginbuehl P., Ellero C., Goff S.A., Glazebrook J.
Plant Mol. Biol. 53:273-279(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-242.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP003221 Genomic DNA. Translation: BAB86423.1.
AP008207 Genomic DNA. Translation: BAF06455.1.
CM000138 Genomic DNA. Translation: EAZ13855.1.
AK073318 mRNA. No translation available.
AY224556 mRNA. Translation: AAO72676.1. Different initiation.
RefSeqNP_001044541.1. NM_001051076.1.
UniGeneOs.88558.

3D structure databases

ProteinModelPortalQ8S2G5.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os01g58740.1; LOC_Os01g58740.1; LOC_Os01g58740.
LOC_Os01g58740.2; LOC_Os01g58740.2; LOC_Os01g58740.
GeneID4327964.
KEGGosa:4327964.

Organism-specific databases

GrameneQ8S2G5.

Phylogenomic databases

OMANIASEVY.
ProtClustDBCLSN2683781.

Gene expression databases

ArrayExpressQ8S2G5.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR011128. G3P_DH_NAD-dep_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERPTHR11728. PTHR11728. 1 hit.
PfamPF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
[Graphical view]
PRINTSPR00077. GPDHDRGNASE.
SUPFAMSSF48179. 6DGDH_C_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGPDH2_ORYSJ
AccessionPrimary (citable) accession number: Q8S2G5
Secondary accession number(s): Q84VD0
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2012
Last sequence update: June 1, 2002
Last modified: April 3, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents