UniProtKB - Q8RYM9 (LAC2_ORYSJ)
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Protein
Laccase-2
Gene
LAC2
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Lignin degradation and detoxification of lignin-derived products.By similarity
Catalytic activityi
4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.
Cofactori
Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 84 | Copper 1By similarity | 1 | |
Metal bindingi | 86 | Copper 2By similarity | 1 | |
Metal bindingi | 129 | Copper 2By similarity | 1 | |
Metal bindingi | 131 | Copper 3By similarity | 1 | |
Metal bindingi | 463 | Copper 4By similarity | 1 | |
Metal bindingi | 466 | Copper 1By similarity | 1 | |
Metal bindingi | 468 | Copper 3By similarity | 1 | |
Metal bindingi | 525 | Copper 3By similarity | 1 | |
Metal bindingi | 526 | Copper 4By similarity | 1 | |
Metal bindingi | 527 | Copper 2By similarity | 1 | |
Metal bindingi | 531 | Copper 4By similarity | 1 |
GO - Molecular functioni
- copper ion binding Source: InterPro
- hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC
- oxidoreductase activity, oxidizing metal ions Source: GO_Central
GO - Biological processi
- lignin catabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Lignin degradation |
Ligand | Copper, Metal-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Laccase-2 (EC:1.10.3.2)Alternative name(s): Benzenediol:oxygen oxidoreductase 2 Diphenol oxidase 2 Urishiol oxidase 2 |
Gene namesi | Name:LAC2 Ordered Locus Names:Os01g0634500, LOC_Os01g44330 ORF Names:OsJ_002637, P0663E10.27 |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 26 | Sequence analysisAdd BLAST | 26 | |
ChainiPRO_0000291887 | 27 – 562 | Laccase-2Add BLAST | 536 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 39 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 53 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 72 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 80 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 118 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 189 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 244 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 300 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 328 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 376 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 386 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 421 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 445 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q8RYM9. |
Expressioni
Gene expression databases
ExpressionAtlasi | Q8RYM9. baseline and differential. |
Genevisiblei | Q8RYM9. OS. |
Structurei
3D structure databases
ProteinModelPortali | Q8RYM9. |
SMRi | Q8RYM9. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 34 – 150 | Plastocyanin-like 1Add BLAST | 117 | |
Domaini | 160 – 312 | Plastocyanin-like 2Add BLAST | 153 | |
Domaini | 411 – 546 | Plastocyanin-like 3Add BLAST | 136 |
Sequence similaritiesi
Belongs to the multicopper oxidase family.Curated
Keywords - Domaini
Repeat, SignalPhylogenomic databases
eggNOGi | KOG1263. Eukaryota. COG2132. LUCA. |
InParanoidi | Q8RYM9. |
KOi | K05909. |
OrthoDBi | EOG09360579. |
Family and domain databases
CDDi | cd13849. CuRO_1_LCC_plant. 1 hit. cd13875. CuRO_2_LCC_plant. 1 hit. cd13897. CuRO_3_LCC_plant. 1 hit. |
Gene3Di | 2.60.40.420. 3 hits. |
InterProi | View protein in InterPro IPR001117. Cu-oxidase. IPR011706. Cu-oxidase_2. IPR011707. Cu-oxidase_3. IPR033138. Cu_oxidase_CS. IPR002355. Cu_oxidase_Cu_BS. IPR008972. Cupredoxin. IPR034288. CuRO_1_LCC. IPR034285. CuRO_2_LCC. IPR034289. CuRO_3_LCC. IPR017761. Laccase. |
Pfami | View protein in Pfam PF00394. Cu-oxidase. 1 hit. PF07731. Cu-oxidase_2. 1 hit. PF07732. Cu-oxidase_3. 1 hit. |
SUPFAMi | SSF49503. SSF49503. 3 hits. |
TIGRFAMsi | TIGR03389. laccase. 1 hit. |
PROSITEi | View protein in PROSITE PS00079. MULTICOPPER_OXIDASE1. 1 hit. PS00080. MULTICOPPER_OXIDASE2. 1 hit. |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q8RYM9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASAASSLPL LVSSLLLALF ALGAHADVKR YQFDIVMSNV SRLCHEKAMV
60 70 80 90 100
TVNGSYPGPT IYAREGDRVI VNVTNHVKHN MTIHWHGLKQ RRNGWADGPA
110 120 130 140 150
YVTQCPIGSG GSYVYDFNVT RQRGTLWWHA HIAWMRATVH GAIVILPAAG
160 170 180 190 200
VPYPFPKPDD EAEIVLGEWW HADVETVERQ GSMLGMAPNM SDAHTINGKP
210 220 230 240 250
GPLVPFCSEK HTYALQVQSG KTYLLRIINA AVNDELFFSI AGHNMTVVEI
260 270 280 290 300
DATYTKPFAA STVQLSPGQT MNVLVSADQS PGRYFMVAKP FNDVPIPADN
310 320 330 340 350
KTATAILQYA GVPTSVVPAL PQTMPATNST GSVAAFHDKL RSLNSPRYPA
360 370 380 390 400
DVPLAVDRHL LYTIGLNIDP CETCLNRSRL AASLNNITFV MPRTALLQAH
410 420 430 440 450
YYGQKGVFAA DFPDRPPARF NYTGVPLTAG LGTSLGTRLS KIAYNATVEL
460 470 480 490 500
VLQDTNLLSV ESHPFHLHGY NFFVVGRGVG NFDPAKDPAK YNLVDPPERN
510 520 530 540 550
TVGVPAGGWT AIRFRADNPG VWFLHCHLEV HTSWGLKMAF LVEDGSGPDE
560
SVLPPPKDLP KC
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 168 | E → D in EAZ12812 (PubMed:15685292).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP004317 Genomic DNA. Translation: BAB90733.1. AP014957 Genomic DNA. No translation available. CM000138 Genomic DNA. Translation: EAZ12812.1. |
RefSeqi | XP_015633503.1. XM_015778017.1. |
Genome annotation databases
EnsemblPlantsi | Os01t0634500-00; Os01t0634500-00; Os01g0634500. |
GeneIDi | 107276614. |
Gramenei | Os01t0634500-00; Os01t0634500-00; Os01g0634500. |
KEGGi | osa:107276614. |
Similar proteinsi
Entry informationi
Entry namei | LAC2_ORYSJ | |
Accessioni | Q8RYM9Primary (citable) accession number: Q8RYM9 Secondary accession number(s): A2ZVR5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 26, 2007 |
Last sequence update: | June 1, 2002 | |
Last modified: | February 28, 2018 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |