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Protein

Laccase-2

Gene

LAC2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Cu cationBy similarityNote: Binds 4 Cu cations per monomer.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi84Copper 1By similarity1
Metal bindingi86Copper 2By similarity1
Metal bindingi129Copper 2By similarity1
Metal bindingi131Copper 3By similarity1
Metal bindingi463Copper 4By similarity1
Metal bindingi466Copper 1By similarity1
Metal bindingi468Copper 3By similarity1
Metal bindingi525Copper 3By similarity1
Metal bindingi526Copper 4By similarity1
Metal bindingi527Copper 2By similarity1
Metal bindingi531Copper 4By similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processLignin degradation
LigandCopper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-2 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 2
Diphenol oxidase 2
Urishiol oxidase 2
Gene namesi
Name:LAC2
Ordered Locus Names:Os01g0634500, LOC_Os01g44330
ORF Names:OsJ_002637, P0663E10.27
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000029188727 – 562Laccase-2Add BLAST536

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi39N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi53N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi72N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi80N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi189N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi244N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi300N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi328N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi376N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi386N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi421N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi445N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ8RYM9

Expressioni

Gene expression databases

ExpressionAtlasiQ8RYM9 differential
GenevisibleiQ8RYM9 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g44330.1

Structurei

3D structure databases

ProteinModelPortaliQ8RYM9
SMRiQ8RYM9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 150Plastocyanin-like 1Add BLAST117
Domaini160 – 312Plastocyanin-like 2Add BLAST153
Domaini411 – 546Plastocyanin-like 3Add BLAST136

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiKOG1263 Eukaryota
COG2132 LUCA
InParanoidiQ8RYM9
KOiK05909
OrthoDBiEOG09360579

Family and domain databases

CDDicd13849 CuRO_1_LCC_plant, 1 hit
cd13875 CuRO_2_LCC_plant, 1 hit
cd13897 CuRO_3_LCC_plant, 1 hit
Gene3Di2.60.40.420, 3 hits
InterProiView protein in InterPro
IPR001117 Cu-oxidase
IPR011706 Cu-oxidase_2
IPR011707 Cu-oxidase_3
IPR033138 Cu_oxidase_CS
IPR002355 Cu_oxidase_Cu_BS
IPR008972 Cupredoxin
IPR034288 CuRO_1_LCC
IPR034285 CuRO_2_LCC
IPR034289 CuRO_3_LCC
IPR017761 Laccase
PfamiView protein in Pfam
PF00394 Cu-oxidase, 1 hit
PF07731 Cu-oxidase_2, 1 hit
PF07732 Cu-oxidase_3, 1 hit
SUPFAMiSSF49503 SSF49503, 3 hits
TIGRFAMsiTIGR03389 laccase, 1 hit
PROSITEiView protein in PROSITE
PS00079 MULTICOPPER_OXIDASE1, 1 hit
PS00080 MULTICOPPER_OXIDASE2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8RYM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASAASSLPL LVSSLLLALF ALGAHADVKR YQFDIVMSNV SRLCHEKAMV
60 70 80 90 100
TVNGSYPGPT IYAREGDRVI VNVTNHVKHN MTIHWHGLKQ RRNGWADGPA
110 120 130 140 150
YVTQCPIGSG GSYVYDFNVT RQRGTLWWHA HIAWMRATVH GAIVILPAAG
160 170 180 190 200
VPYPFPKPDD EAEIVLGEWW HADVETVERQ GSMLGMAPNM SDAHTINGKP
210 220 230 240 250
GPLVPFCSEK HTYALQVQSG KTYLLRIINA AVNDELFFSI AGHNMTVVEI
260 270 280 290 300
DATYTKPFAA STVQLSPGQT MNVLVSADQS PGRYFMVAKP FNDVPIPADN
310 320 330 340 350
KTATAILQYA GVPTSVVPAL PQTMPATNST GSVAAFHDKL RSLNSPRYPA
360 370 380 390 400
DVPLAVDRHL LYTIGLNIDP CETCLNRSRL AASLNNITFV MPRTALLQAH
410 420 430 440 450
YYGQKGVFAA DFPDRPPARF NYTGVPLTAG LGTSLGTRLS KIAYNATVEL
460 470 480 490 500
VLQDTNLLSV ESHPFHLHGY NFFVVGRGVG NFDPAKDPAK YNLVDPPERN
510 520 530 540 550
TVGVPAGGWT AIRFRADNPG VWFLHCHLEV HTSWGLKMAF LVEDGSGPDE
560
SVLPPPKDLP KC
Length:562
Mass (Da):61,296
Last modified:June 1, 2002 - v1
Checksum:i0BF4F84B9E7996A9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti168E → D in EAZ12812 (PubMed:15685292).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004317 Genomic DNA Translation: BAB90733.1
AP014957 Genomic DNA No translation available.
CM000138 Genomic DNA Translation: EAZ12812.1
RefSeqiXP_015633503.1, XM_015778017.1

Genome annotation databases

EnsemblPlantsiOs01t0634500-00; Os01t0634500-00; Os01g0634500
GeneIDi107276614
GrameneiOs01t0634500-00; Os01t0634500-00; Os01g0634500
KEGGiosa:107276614

Similar proteinsi

Entry informationi

Entry nameiLAC2_ORYSJ
AccessioniPrimary (citable) accession number: Q8RYM9
Secondary accession number(s): A2ZVR5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 1, 2002
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

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