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Protein

Long chain base biosynthesis protein 2c

Gene

Os01g0928700

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1 constitutes the catalytic core (By similarity).By similarity

Catalytic activityi

Palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2.

Cofactori

Pathwayi: sphingolipid metabolism

This protein is involved in the pathway sphingolipid metabolism, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway sphingolipid metabolism and in Lipid metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Lipid metabolism, Sphingolipid metabolism

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00222.

Names & Taxonomyi

Protein namesi
Recommended name:
Long chain base biosynthesis protein 2c (EC:2.3.1.50)
Gene namesi
Ordered Locus Names:Os01g0928700, LOC_Os01g70370
ORF Names:OsJ_04634, OSJNBa0052O12.13
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei4 – 24HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004191521 – 497Long chain base biosynthesis protein 2cAdd BLAST497

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei319N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiQ8RYL0.

Expressioni

Gene expression databases

GenevisibleiQ8RYL0. OS.

Interactioni

Subunit structurei

Heterodimer with LCB1. Component of the serine palmitoyltransferase (SPT) complex, composed of LCB1 and LCB2 (By similarity).By similarity

Protein-protein interaction databases

STRINGi39947.LOC_Os01g70370.1.

Structurei

3D structure databases

ProteinModelPortaliQ8RYL0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1357. Eukaryota.
COG0156. LUCA.
InParanoidiQ8RYL0.
KOiK00654.
OMAiDELCHAS.
OrthoDBiEOG0936074X.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8RYL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVRVPFVTAV TTVFSYGVIF GFGHLRDWFR ALLRSLFSGH SPAAAGTNLK
60 70 80 90 100
GYAPICGGQE DFYYRRFVRR VQDCFWRPIA SKPDAWFDVV ERYSNDSNKT
110 120 130 140 150
LHRTTKTSRC LNLGSYNYLG FAAADEYCTP RVIESLKKYS ASTCSVRVDG
160 170 180 190 200
GNTKLHVELE ELVARFVGKP AAILFGMGYV TNSAIIPALI GKGGLIISDS
210 220 230 240 250
LNHNSIVNGA RGSGASVQVF QHNNPAHLEE VLREQIAGGQ PRTHRRWKKI
260 270 280 290 300
IVIVEGIYSM EGELCKLPEI VAVCKKYKAY TYLDEAHSIG AVGKTGRGVC
310 320 330 340 350
ELLGVDPADV DIMMGTFTKS FGSCGGYIAA SKEIIDHLKH ICPAHIYATS
360 370 380 390 400
MSPPAVQQVI SAIEVILGED GSDRGAKKLA QIRENSNFFR SELEKMGFEV
410 420 430 440 450
LGDNDSPVMP IMLYNPAKMP AFSRECLRQK VAIVTVSFPA TPLLLARARI
460 470 480 490
CISASHSRED LIKGLEVISK VGDLVGIKYL PVEHEKTTSA EKLKKIQ
Length:497
Mass (Da):54,647
Last modified:June 1, 2002 - v1
Checksum:i7EF5833AA6538DB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004330 Genomic DNA. Translation: BAB90752.1.
AP008207 Genomic DNA. Translation: BAF07192.1.
AP014957 Genomic DNA. Translation: BAS76015.1.
CM000138 Genomic DNA. Translation: EAZ14710.1.
RefSeqiXP_015613384.1. XM_015757898.1.

Genome annotation databases

EnsemblPlantsiOS01T0928700-00; OS01T0928700-00; OS01G0928700.
GeneIDi4326965.
GrameneiOS01T0928700-00; OS01T0928700-00; OS01G0928700.
KEGGiosa:4326965.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP004330 Genomic DNA. Translation: BAB90752.1.
AP008207 Genomic DNA. Translation: BAF07192.1.
AP014957 Genomic DNA. Translation: BAS76015.1.
CM000138 Genomic DNA. Translation: EAZ14710.1.
RefSeqiXP_015613384.1. XM_015757898.1.

3D structure databases

ProteinModelPortaliQ8RYL0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g70370.1.

Proteomic databases

PaxDbiQ8RYL0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0928700-00; OS01T0928700-00; OS01G0928700.
GeneIDi4326965.
GrameneiOS01T0928700-00; OS01T0928700-00; OS01G0928700.
KEGGiosa:4326965.

Phylogenomic databases

eggNOGiKOG1357. Eukaryota.
COG0156. LUCA.
InParanoidiQ8RYL0.
KOiK00654.
OMAiDELCHAS.
OrthoDBiEOG0936074X.

Enzyme and pathway databases

UniPathwayiUPA00222.

Gene expression databases

GenevisibleiQ8RYL0. OS.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLCB2C_ORYSJ
AccessioniPrimary (citable) accession number: Q8RYL0
Secondary accession number(s): A0A0P0VCB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: June 1, 2002
Last modified: November 30, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.