Reviewed,
UniProtKB/Swiss-Prot Q8RY89 (PI5K8_ARATH)
Last modified
June 16, 2009.
Version 46.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
Customize display | text xml rdf/xml gff fasta |
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Phosphatidylinositol-4-phosphate 5-kinase 8 Short name=AtPIP5K8 EC=2.7.1.68 Alternative name(s): 1-phosphatidylinositol-4-phosphate kinase 8 PtdIns(4)P-5-kinase 8 Diphosphoinositide kinase 8 | ||||||
| Gene names |
| ||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids II › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 769 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. |
| Sequence similarities | Contains 8 MORN repeats. Contains 1 PI5K domain. |
| Sequence caution | The sequence AAG51639.1 differs from that shown. Reason: Erroneous gene model prediction. |
Ontologies
| Keywords | |
|---|---|
| Domain | Repeat |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Kinase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | phosphatidylinositol metabolic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | plasma membrane Inferred from direct assay. Source: TAIR |
| Molecular function | 1-phosphatidylinositol-4-phosphate 5-kinase activity Inferred from electronic annotation. Source: EC ATP bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 769 | 769 | Phosphatidylinositol-4-phosphate 5-kinase 8 | PRO_0000185480 | |||||
Regions | |||||||||
| Repeat | 16 – 38 | 23 | MORN 1 | ||||||
| Repeat | 39 – 61 | 23 | MORN 2 | ||||||
| Repeat | 62 – 84 | 23 | MORN 3 | ||||||
| Repeat | 85 – 107 | 23 | MORN 4 | ||||||
| Repeat | 108 – 130 | 23 | MORN 5 | ||||||
| Repeat | 131 – 153 | 23 | MORN 6 | ||||||
| Repeat | 154 – 176 | 23 | MORN 7 | ||||||
| Repeat | 177 – 198 | 22 | MORN 8 | ||||||
| Domain | 428 – 765 | 338 | PI5K | ||||||
| Region | 725 – 746 | 22 | Activation loop By similarity | ||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. Davis R.W.Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [2] | "Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. Ecker J.R.Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Columbia. |
| [3] | "Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C." Mueller-Roeber B., Pical C. Plant Physiol. 130:22-46(2002) [PubMed: 12226484] [Abstract] Cited for: GENE FAMILY, NOMENCLATURE. |
Cross-references
Sequence databases | |
|---|---|
| AC018908 Genomic DNA. Translation: AAG51639.1. Sequence problems. AY074507 mRNA. Translation: AAL69491.1. AY133824 mRNA. Translation: AAM91758.1. | |
| IPI | IPI00547011. |
| PIR | D96634. |
| RefSeq | NP_176286.2. |
| UniGene | At.28792 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1BO1 based on UniProtKB P78356. |
| ModBase | Search... |
Proteomic databases | |
| PRIDE | Q8RY89. |
Genome annotation databases | |
| GeneID | 842381. |
| GenomeReviews | Gene locus AT1G60890 in contig CT485782_GR. |
| KEGG | ath:AT1G60890. |
| NMPDR | fig|3702.1.peg.5471. |
Organism-specific databases | |
| TAIR | At1g60890. |
Phylogenomic databases | |
| OMA | Q8RY89. RSYYLML. |
Enzyme and pathway databases | |
| BRENDA | 2.7.1.68. 302. |
Gene expression databases | |
| ArrayExpress | Q8RY89. |
| GermOnline | AT1G60890. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR003409. MORN. IPR017163. PIno-4-P-5_kinase_pln. IPR002498. PInositol-4-P-5-kinase_core. IPR016034. PInositol-4P-5-kinase_core_sub. [Graphical view] |
| PANTHER | PTHR23086. PIP5K. 1 hit. |
| Pfam | PF02493. MORN. 8 hits. PF01504. PIP5K. 1 hit. [Graphical view] |
| PIRSF | PIRSF037274. PIP5K_plant_prd. 1 hit. |
| SMART | SM00698. MORN. 8 hits. SM00330. PIPKc. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | PI5K8_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q8RY89 Secondary accession number(s): Q9C962 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with


