Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ABC transporter G family member 11

Gene

ABCG11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Required for the cuticle and pollen coat development by controlling cutin and maybe wax transport to the extracellular matrix. Involved in developmental plasticity and stress responses.5 Publications

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi87 – 94ATPPROSITE-ProRule annotation8

GO - Molecular functioni

  • ATPase activity, coupled to transmembrane movement of substances Source: GO_Central
  • ATP binding Source: UniProtKB-KW
  • fatty acid transporter activity Source: TAIR
  • protein homodimerization activity Source: TAIR

GO - Biological processi

  • cotyledon vascular tissue pattern formation Source: TAIR
  • cutin transport Source: TAIR
  • fatty acid transport Source: TAIR
  • response to abscisic acid Source: UniProtKB
  • response to salt stress Source: UniProtKB
  • response to wounding Source: UniProtKB
  • stem vascular tissue pattern formation Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-1369062. ABC transporters in lipid homeostasis.
R-ATH-265473. Trafficking of dietary sterols.

Protein family/group databases

TCDBi3.A.1.204.8. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter G family member 11
Short name:
ABC transporter ABCG.11
Short name:
AtABCG11
Alternative name(s):
Protein CUTICULAR DEFECT AND ORGAN FUSION 1
Protein DESPERADO
Protein PERMEABLE LEAVES 1
White-brown complex homolog protein 11
Short name:
AtWBC11
Gene namesi
Name:ABCG11
Synonyms:COF1, DSO, PEL1, WBC11
Ordered Locus Names:At1g17840
ORF Names:F2H15.7
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G17840.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei406 – 426HelicalSequence analysisAdd BLAST21
Transmembranei436 – 456HelicalSequence analysisAdd BLAST21
Transmembranei485 – 505HelicalSequence analysisAdd BLAST21
Transmembranei513 – 533HelicalSequence analysisAdd BLAST21
Transmembranei540 – 560HelicalSequence analysisAdd BLAST21
Transmembranei628 – 648HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • external side of plasma membrane Source: TAIR
  • integral component of membrane Source: GO_Central
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Bushy phenotype. Abnormal cuticle and pollen grain shapes, reduced levels of wax and cutin monomers, unusual lipidic cytoplasmatic inclusions in epidermal cells, inter-organ postgenital fusions, and altered morphology of trichomes and pavement cells. Highly susceptibility to salt and reduced root branching.5 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002406831 – 703ABC transporter G family member 11Add BLAST703

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei688PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ8RXN0.
PRIDEiQ8RXN0.

PTM databases

iPTMnetiQ8RXN0.

Expressioni

Tissue specificityi

Expressed in seedlings, roots, stems, leaves, flowers, and siliques, mostly in epidermis, trichomes, vasculatures and developing tissues.4 Publications

Developmental stagei

First observed in seed coat and the endosperm. During embryo development, expressed in the radical tip. In seedlings, localized in the cotyledons, root tip, and young leaves. As secondary root tips emerge, expressed in the pericycle during the initial cell divisions. In leaves, mostly detected in the expanding basal portion, trichomes and stomatal cells. In roots of mature plants, mainly expressed in lateral root primordia and developing lateral roots. In the inflorescence, found in all floral organs, predominantly in the anthers, styles, and young siliques. Upon anthesis and later, progressively restricted to the carpel.2 Publications

Inductioni

By light, NaCl, abscisic acid (ABA), wounding, and glucose stresses. Repressed by H2O2 and cytokinin.3 Publications

Gene expression databases

GenevisibleiQ8RXN0. AT.

Interactioni

Subunit structurei

Homodimer.Curated

GO - Molecular functioni

  • protein homodimerization activity Source: TAIR

Protein-protein interaction databases

BioGridi23602. 18 interactors.
STRINGi3702.AT1G17840.1.

Structurei

3D structure databases

ProteinModelPortaliQ8RXN0.
SMRiQ8RXN0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini50 – 293ABC transporterPROSITE-ProRule annotationAdd BLAST244
Domaini382 – 594ABC transmembrane type-2Add BLAST213

Sequence similaritiesi

Contains 1 ABC transporter domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0061. Eukaryota.
COG1131. LUCA.
HOGENOMiHOG000166547.
InParanoidiQ8RXN0.
OMAiKMPMEEK.
OrthoDBiEOG093603FV.
PhylomeDBiQ8RXN0.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8RXN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIEASRQQT TVPVSVGGGN FPVGGLSPLS EAIWREKAPT EFVGDVSARL
60 70 80 90 100
TWQDLTVMVT MGDGETQNVL EGLTGYAEPG SLTALMGPSG SGKSTMLDAL
110 120 130 140 150
ASRLAANAFL SGTVLLNGRK TKLSFGTAAY VTQDDNLIGT LTVRETIWYS
160 170 180 190 200
ARVRLPDKML RSEKRALVER TIIEMGLQDC ADTVIGNWHL RGISGGEKRR
210 220 230 240 250
VSIALEILMR PRLLFLDEPT SGLDSASAFF VTQTLRALSR DGRTVIASIH
260 270 280 290 300
QPSSEVFELF DRLYLLSGGK TVYFGQASDA YEFFAQAGFP CPALRNPSDH
310 320 330 340 350
FLRCINSDFD KVRATLKGSM KLRFEASDDP LEKITTAEAI RLLVDYYHTS
360 370 380 390 400
DYYYTAKAKV EEISQFKGTI LDSGGSQASF LLQTYTLTKR SFINMSRDFG
410 420 430 440 450
YYWLRLLIYI LVTVCIGTIY LNVGTSYSAI LARGSCASFV FGFVTFMSIG
460 470 480 490 500
GFPSFVEDMK VFQRERLNGH YGVAAFVIAN TLSATPFLIM ITFISGTICY
510 520 530 540 550
FMVGLHPGFT HYLFFVLCLY ASVTVVESLM MAIASIVPNF LMGIIIGAGI
560 570 580 590 600
QGIFMLVSGF FRLPNDIPKP FWRYPMSYIS FHFWALQGQY QNDLRGLTFD
610 620 630 640 650
SQGSAFKIPG EYVLENVFQI DLHRSKWINL SVILSMIIIY RIIFFIMIKT
660 670 680 690 700
NEDVTPWVRG YIARRRMKQK NGTQNTTVAP DGLTQSPSLR NYIATRTDGA

RRW
Length:703
Mass (Da):78,413
Last modified:June 1, 2002 - v1
Checksum:i8D85EE940AC39003
GO

Sequence cautioni

The sequence AAF97264 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC034106 Genomic DNA. Translation: AAF97264.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE29642.1.
AY080792 mRNA. Translation: AAL87274.1.
AY150457 mRNA. Translation: AAN12898.1.
PIRiE86313.
RefSeqiNP_173226.2. NM_101647.5.
UniGeneiAt.41813.
At.70679.
At.74421.
At.75384.

Genome annotation databases

EnsemblPlantsiAT1G17840.1; AT1G17840.1; AT1G17840.
GeneIDi838363.
GrameneiAT1G17840.1; AT1G17840.1; AT1G17840.
KEGGiath:AT1G17840.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC034106 Genomic DNA. Translation: AAF97264.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE29642.1.
AY080792 mRNA. Translation: AAL87274.1.
AY150457 mRNA. Translation: AAN12898.1.
PIRiE86313.
RefSeqiNP_173226.2. NM_101647.5.
UniGeneiAt.41813.
At.70679.
At.74421.
At.75384.

3D structure databases

ProteinModelPortaliQ8RXN0.
SMRiQ8RXN0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi23602. 18 interactors.
STRINGi3702.AT1G17840.1.

Protein family/group databases

TCDBi3.A.1.204.8. the atp-binding cassette (abc) superfamily.

PTM databases

iPTMnetiQ8RXN0.

Proteomic databases

PaxDbiQ8RXN0.
PRIDEiQ8RXN0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G17840.1; AT1G17840.1; AT1G17840.
GeneIDi838363.
GrameneiAT1G17840.1; AT1G17840.1; AT1G17840.
KEGGiath:AT1G17840.

Organism-specific databases

TAIRiAT1G17840.

Phylogenomic databases

eggNOGiKOG0061. Eukaryota.
COG1131. LUCA.
HOGENOMiHOG000166547.
InParanoidiQ8RXN0.
OMAiKMPMEEK.
OrthoDBiEOG093603FV.
PhylomeDBiQ8RXN0.

Enzyme and pathway databases

ReactomeiR-ATH-1369062. ABC transporters in lipid homeostasis.
R-ATH-265473. Trafficking of dietary sterols.

Miscellaneous databases

PROiQ8RXN0.

Gene expression databases

GenevisibleiQ8RXN0. AT.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013525. ABC_2_trans.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01061. ABC2_membrane. 1 hit.
PF00005. ABC_tran. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAB11G_ARATH
AccessioniPrimary (citable) accession number: Q8RXN0
Secondary accession number(s): Q9LMU4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: June 1, 2002
Last modified: November 30, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.