Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable protein phosphatase 2C 2

Gene

At1g07160

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi158 – 1581Manganese 1By similarity
Metal bindingi158 – 1581Manganese 2By similarity
Metal bindingi159 – 1591Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi321 – 3211Manganese 2By similarity
Metal bindingi367 – 3671Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G07160-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 2 (EC:3.1.3.16)
Short name:
AtPP2C02
Alternative name(s):
Protein phosphatase AP2C2
Gene namesi
Ordered Locus Names:At1g07160
ORF Names:F10K1.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G07160.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 380380Probable protein phosphatase 2C 2PRO_0000367936Add
BLAST

Proteomic databases

PRIDEiQ8RX37.

Expressioni

Gene expression databases

ExpressionAtlasiQ8RX37. baseline and differential.
GenevestigatoriQ8RX37.

Interactioni

Protein-protein interaction databases

BioGridi22468. 1 interaction.
IntActiQ8RX37. 1 interaction.
STRINGi3702.AT1G07160.1-P.

Structurei

3D structure databases

ProteinModelPortaliQ8RX37.
SMRiQ8RX37. Positions 99-376.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini122 – 376255PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ8RX37.
OMAiEINILRI.
PhylomeDBiQ8RX37.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8RX37-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSVAVCNS PVFSPSSSLF CNKPLNTSPA HETLTLSLSH LNPPVSSTSP
60 70 80 90 100
SAASPTSPFC LRLLKPPAKL GFGSDSGPGS ILKRKRPTTL DIPVAPVGIA
110 120 130 140 150
APISNADTPR EESRAVEREG DGYSVYCKRG KREAMEDRFS AITNLQGDPK
160 170 180 190 200
QAIFGVYDGH GGPTAAEFAA KNLCSNILGE IVGGRNESKI EEAVKRGYLA
210 220 230 240 250
TDSEFLKEKN VKGGSCCVTA LISDGNLVVA NAGDCRAVLS VGGFAEALTS
260 270 280 290 300
DHRPSRDDER NRIESSGGYV DTFNSVWRIQ GSLAVSRGIG DAHLKQWIIS
310 320 330 340 350
EPEINILRIN PQHEFLILAS DGLWDKVSNQ EAVDIARPFC KGTDQKRKPL
360 370 380
LACKKLVDLS VSRGSLDDIS VMLIQLCHLF
Length:380
Mass (Da):40,709
Last modified:June 1, 2002 - v1
Checksum:i7EA1D8B991F0E88D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067971 Genomic DNA. Translation: AAF82204.1.
CP002684 Genomic DNA. Translation: AEE28084.1.
AY090917 mRNA. Translation: AAM13912.1.
PIRiF86206.
RefSeqiNP_172196.1. NM_100590.3.
UniGeneiAt.42311.

Genome annotation databases

EnsemblPlantsiAT1G07160.1; AT1G07160.1; AT1G07160.
GeneIDi837227.
KEGGiath:AT1G07160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC067971 Genomic DNA. Translation: AAF82204.1.
CP002684 Genomic DNA. Translation: AEE28084.1.
AY090917 mRNA. Translation: AAM13912.1.
PIRiF86206.
RefSeqiNP_172196.1. NM_100590.3.
UniGeneiAt.42311.

3D structure databases

ProteinModelPortaliQ8RX37.
SMRiQ8RX37. Positions 99-376.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi22468. 1 interaction.
IntActiQ8RX37. 1 interaction.
STRINGi3702.AT1G07160.1-P.

Proteomic databases

PRIDEiQ8RX37.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G07160.1; AT1G07160.1; AT1G07160.
GeneIDi837227.
KEGGiath:AT1G07160.

Organism-specific databases

GeneFarmi3527. 320.
TAIRiAT1G07160.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ8RX37.
OMAiEINILRI.
PhylomeDBiQ8RX37.

Enzyme and pathway databases

BioCyciARA:AT1G07160-MONOMER.

Miscellaneous databases

PROiQ8RX37.

Gene expression databases

ExpressionAtlasiQ8RX37. baseline and differential.
GenevestigatoriQ8RX37.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C02_ARATH
AccessioniPrimary (citable) accession number: Q8RX37
Secondary accession number(s): Q9LMK9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 1, 2002
Last modified: April 29, 2015
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.