##gff-version 3
Q8RX28	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22223895;Dbxref=PMID:22223895	
Q8RX28	UniProtKB	Chain	2	660	.	.	.	ID=PRO_0000280084;Note=Histone deacetylase 5	
Q8RX28	UniProtKB	Region	26	349	.	.	.	Note=Histone deacetylase	
Q8RX28	UniProtKB	Active site	158	158	.	.	.	Note=Proton donor/acceptor;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8GXJ1	
Q8RX28	UniProtKB	Binding site	198	198	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8GXJ1	
Q8RX28	UniProtKB	Binding site	200	200	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8GXJ1	
Q8RX28	UniProtKB	Binding site	291	291	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8GXJ1	
Q8RX28	UniProtKB	Site	331	331	.	.	.	Note=Polarizes the scissile carbonyl of the substrate;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q8GXJ1	
Q8RX28	UniProtKB	Modified residue	2	2	.	.	.	Note=N-acetylalanine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:22223895;Dbxref=PMID:22223895	
Q8RX28	UniProtKB	Mutagenesis	198	198	.	.	.	Note=Loss of enzymatic activity. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25922987;Dbxref=PMID:25922987	
Q8RX28	UniProtKB	Mutagenesis	200	200	.	.	.	Note=Loss of enzymatic activity. H->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25922987;Dbxref=PMID:25922987	
Q8RX28	UniProtKB	Mutagenesis	291	291	.	.	.	Note=Loss of enzymatic activity. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25922987;Dbxref=PMID:25922987