Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Calpain-type cysteine protease DEK1

Gene

DEK1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Essential protein involved in epiderm development. Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization. Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion. Does not need calcium ions to be active. Required for the formation of giant cells in sepals by determining cell fate and promoting endoreplication.5 Publications

Catalytic activityi

Broad endopeptidase specificity.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei1761By similarity1
Active sitei1919By similarity1
Active sitei1939By similarity1

GO - Molecular functioni

  • calcium-dependent cysteine-type endopeptidase activity Source: GO_Central
  • cysteine-type peptidase activity Source: UniProtKB

GO - Biological processi

  • embryo development ending in seed dormancy Source: UniProtKB
  • epidermal cell fate specification Source: UniProtKB
  • positive regulation of DNA endoreduplication Source: UniProtKB
  • regulation of adaxial/abaxial pattern formation Source: UniProtKB
  • regulation of cell growth Source: UniProtKB
  • regulation of cell proliferation Source: UniProtKB
  • regulation of endosperm development Source: UniProtKB
  • regulation of leaf development Source: UniProtKB
  • regulation of meristem structural organization Source: UniProtKB
  • self proteolysis Source: UniProtKB
  • sepal giant cell differentiation Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Hydrolase, Protease, Thiol protease

Protein family/group databases

MEROPSiC02.019.

Names & Taxonomyi

Protein namesi
Recommended name:
Calpain-type cysteine protease DEK1 (EC:3.4.22.-)
Alternative name(s):
Phytocalpain DEK1
Protein DEFECTIVE KERNEL 1
Short name:
AtDEK1
Protein EMBRYO DEFECTIVE 1275
Protein EMBRYO DEFECTIVE 80
Gene namesi
Name:DEK1
Synonyms:EMB1275, EMB80
Ordered Locus Names:At1g55350
ORF Names:F7A10.23
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G55350.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini33 – 69ExtracellularSequence analysisAdd BLAST37
Transmembranei70 – 90Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini91 – 94CytoplasmicSequence analysis4
Transmembranei95 – 115Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini116 – 126ExtracellularSequence analysisAdd BLAST11
Transmembranei127 – 147Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini148 – 163CytoplasmicSequence analysisAdd BLAST16
Transmembranei164 – 184Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini185 – 235ExtracellularSequence analysisAdd BLAST51
Transmembranei236 – 256Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini257 – 263CytoplasmicSequence analysis7
Transmembranei264 – 284Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini285 – 293ExtracellularSequence analysis9
Transmembranei294 – 314Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini315 – 319CytoplasmicSequence analysis5
Transmembranei320 – 340Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini341 – 615ExtracellularSequence analysisAdd BLAST275
Transmembranei616 – 636Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini637 – 652CytoplasmicSequence analysisAdd BLAST16
Transmembranei653 – 673Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini674 – 686ExtracellularSequence analysisAdd BLAST13
Transmembranei687 – 707Helical; Name=11Sequence analysisAdd BLAST21
Topological domaini708 – 711CytoplasmicSequence analysis4
Transmembranei712 – 732Helical; Name=12Sequence analysisAdd BLAST21
Topological domaini733 – 760ExtracellularSequence analysisAdd BLAST28
Transmembranei761 – 782Helical; Name=13Sequence analysisAdd BLAST22
Topological domaini783 – 813CytoplasmicSequence analysisAdd BLAST31
Transmembranei814 – 834Helical; Name=14Sequence analysisAdd BLAST21
Topological domaini835 – 844ExtracellularSequence analysis10
Transmembranei845 – 865Helical; Name=15Sequence analysisAdd BLAST21
Topological domaini866 – 878CytoplasmicSequence analysisAdd BLAST13
Transmembranei879 – 899Helical; Name=16Sequence analysisAdd BLAST21
Topological domaini900 – 912ExtracellularSequence analysisAdd BLAST13
Transmembranei913 – 933Helical; Name=17Sequence analysisAdd BLAST21
Topological domaini934 – 936CytoplasmicSequence analysis3
Transmembranei937 – 957Helical; Name=18Sequence analysisAdd BLAST21
Topological domaini958 – 971ExtracellularSequence analysisAdd BLAST14
Transmembranei972 – 992Helical; Name=19Sequence analysisAdd BLAST21
Topological domaini993 – 1006CytoplasmicSequence analysisAdd BLAST14
Transmembranei1007 – 1027Helical; Name=20Sequence analysisAdd BLAST21
Topological domaini1028 – 1050ExtracellularSequence analysisAdd BLAST23
Transmembranei1051 – 1071Helical; Name=21Sequence analysisAdd BLAST21
Topological domaini1072 – 2151CytoplasmicSequence analysisAdd BLAST1080

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • endoplasmic reticulum membrane Source: UniProtKB
  • endosome membrane Source: UniProtKB
  • integral component of plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Endoplasmic reticulum, Endosome, Membrane

Pathology & Biotechi

Disruption phenotypei

Defective embryo arrested at preglobular/globular stage. Disturbed endosperm lacking the aleurone-like peripheral cell layer and unorganized embryo development displaying irregular mitotic divisions in the embryo proper and suspensor. In a partially disrupted phenotype, impaired meristems organization characterized by vacuolated cells, abnormal cotyledon epiderm made of chloroplast-containing cells, and radialized leaves.6 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi1761C → S: Loss of activity. 1 Publication1
Mutagenesisi2106R → C in dek1-4; near absence of giant cells in sepals due to a reduced endoreduplication. 1 Publication1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 32Sequence analysisAdd BLAST32
ChainiPRO_000042343733 – 2151Calpain-type cysteine protease DEK1Add BLAST2119
PropeptideiPRO_000042343833 – ?

Post-translational modificationi

Autocatalytic proteolytic cleavage leading to the production of mainly cytoplasmic localized subproducts of about 85 and 120 kDa.

Proteomic databases

PaxDbiQ8RVL2.

PTM databases

iPTMnetiQ8RVL2.

Expressioni

Tissue specificityi

Mostly expressed in meristems and organ primordia. Expressed at low levels in young and germinating seeds at 10 ppm and in seedling roots at 67 ppm. Present in most tissues at a low level.2 Publications

Developmental stagei

Mostly observed in vegetative, inflorescence and floral meristems as well as in young leaf and floral organ primordia. Strongly expressed in developing ovules and during early embryogenesis. Expressed evenly throughout the endosperm and the embryo in developing seed. Present in the embryo proper, but excluded from the suspensor, until the late heart stage, and fades out later, especially in the hypocotyl region, to be present at low levels throughout walking-stick embryos. Accumulates at the margins and in the tips of cotyledons and lateral organs, in the apical meristem, in a subset of cells at the root pole and in a restricted number of cells within the presumptive vasculature of the hypocotyls. Also detected during early endosperm development, prior to cellularization.2 Publications

Gene expression databases

ExpressionAtlasiQ8RVL2. baseline and differential.
GenevisibleiQ8RVL2. AT.

Interactioni

Protein-protein interaction databases

BioGridi27206. 2 interactors.
IntActiQ8RVL2. 1 interactor.
STRINGi3702.AT1G55350.5.

Structurei

3D structure databases

ProteinModelPortaliQ8RVL2.
SMRiQ8RVL2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1407 – 1600Calpain catalytic 1PROSITE-ProRule annotationAdd BLAST194
Domaini1695 – 1997Calpain catalytic 2PROSITE-ProRule annotationAdd BLAST303

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi369 – 485Ser-richAdd BLAST117
Compositional biasi1595 – 1636Asp-richAdd BLAST42

Domaini

The transmembrane regions are not required for calpain activity but may play regulatory roles.1 Publication

Sequence similaritiesi

Belongs to the peptidase C2 family.Curated
Contains 2 calpain catalytic domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000030613.
PhylomeDBiQ8RVL2.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
Gene3Di2.60.120.200. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR013320. ConA-like_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF49758. SSF49758. 1 hit.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: Additional isoforms may exist.
Isoform 1 (identifier: Q8RVL2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEGDERGVLL ACVISGTLFT VFGSGSFWIL WAVNWRPWRL YSWIFARKWP
60 70 80 90 100
KVLQGPQLDI LCGVLSLFAW IVVVSPIAIL IGWGSWLIVI LDRHIIGLAI
110 120 130 140 150
IMAGTALLLA FYSIMLWWRT QWQSSRAVAL LLLLGVALLC AYELCAVYVT
160 170 180 190 200
AGAHASQQYS PSGFFFGVSA IALAINMLFI CRMVFNGNGL DVDEYVRRAY
210 220 230 240 250
KFAYSDCIEV GPVACLPEPP DPNELYPRQT SRASHLGLLY LGSLVVLLAY
260 270 280 290 300
SVLYGLTARE SRWLGGITSA AVIVLDWNIG ACLYGFKLLQ NRVLALFVAG
310 320 330 340 350
ISRLFLICFG IHYWYLGHCI SYIFVASVLS GAAVSRHLSI TDPSAARRDA
360 370 380 390 400
LQSTVIRLRE GFRRKEQNSS SSSSDGCGSS IKRSSSIDAG HTGCTNEANR
410 420 430 440 450
TAESCTADNL TRTGSSQEGI NSDKSEESGR PSLGLRSSSC RSVVQEPEAG
460 470 480 490 500
TSYFMDKVSD QNNTLVVCSS SGLDSQGYES STSNSANQQL LDMNLALAFQ
510 520 530 540 550
DQLNNPRIAS ILKKKAKEGD LELTNLLQDK GLDPNFAVML KEKNLDPTIL
560 570 580 590 600
ALLQRSSLDA DRDHRDNTDI TIIDSNSVDN TLPNQISLSE ELRLRGLEKW
610 620 630 640 650
LKLSRLLLHH VAGTPERAWG LFSLVFILET IIVAIFRPKT ITIINSSHQQ
660 670 680 690 700
FEFGFSVLLL SPVVCSIMAF LRSLQVEEMA LTSKSRKYGF VAWLLSTSVG
710 720 730 740 750
LSLSFLSKSS VLLGISLTVP LMAACLSIAV PIWMHNGYQF WVPQLSCGDQ
760 770 780 790 800
ARDLRSPRIK GFILWICVVL FAGSVISLGA IISAKPLDDL KYKLFSAREN
810 820 830 840 850
NVTSPYTSSV YLGWAMSSGI ALVVTAILPI VSWFATYRFS HSSAVCLMIF
860 870 880 890 900
SVVLVAFCGT SYLEVVKSRD DQLPTKGDFL AALLPLACIP ALLSLCCGMV
910 920 930 940 950
KWKDDCWILS RGVYVFFSIG LLLLFGAIAA VIAVKPWTIG VSFLLVLFLM
960 970 980 990 1000
VVTIGVIHLW ASNNFYLTRK QTSFVCFLAL LLGLAAFLLG WHQDKAFAGA
1010 1020 1030 1040 1050
SVGYFTFLSL LAGRALAVLL SPPIVVYSPR VLPVYVYDAH ADCGKNVSAA
1060 1070 1080 1090 1100
FLVLYGIALA TEGWGVVASL IIYPPFAGAA VSAITLVVAF GFAVSRPCLT
1110 1120 1130 1140 1150
LEMMEVAVRF LSKDTIVQAI SRSATKTRNA LSGTYSAPQR SASSAALLVG
1160 1170 1180 1190 1200
DPSAMRDKAG NFVLPRDDVM KLRDRLRNEE RVAGSIFYKM QCRKGFRHEP
1210 1220 1230 1240 1250
PTNVDYRRDM CAHARVLALE EAIDTEWVYM WDKFGGYLLL LLGLTAKAER
1260 1270 1280 1290 1300
VQDEVRLRLF LDSIGFSDLS ARKISKWKPE DRRQFEIIQE SYLREKEMEE
1310 1320 1330 1340 1350
ESLMQRREEE GRGKERRKAL LEKEERKWKE IEASLIPSIP NAGSREAAAM
1360 1370 1380 1390 1400
AAAIRAVGGD SVLEDSFARE RVSGIARRIR TAQLERRAQQ TGISGAVCVL
1410 1420 1430 1440 1450
DDEPMISGKH CGQMDSSVCQ SQKISFSVTA MIQSDSGPVC LFGTEFQKKV
1460 1470 1480 1490 1500
CWEILVAGSE QGIEAGQVGL RLITKGERQT TVAREWYIGA TSITDGRWHT
1510 1520 1530 1540 1550
VTITIDADAG EATCYIDGGF DGYQNGLPLS IGSAIWEQGA EVWLGVRPPI
1560 1570 1580 1590 1600
DVDAFGRSDS DGVESKMHIM DVFLWGKCLS EEEAASLHAA IGMADLDMID
1610 1620 1630 1640 1650
LSDDNWQWTD SPPRVDGWDS DPADVDLYDR DDVDWDGQYS SGRKRRSGRD
1660 1670 1680 1690 1700
FVMSVDSFAR RHRKPRMETQ EDINQRMRSV ELAVKEALSA RGDKQFTDQE
1710 1720 1730 1740 1750
FPPNDRSLFV DTQNPPSKLQ VVSEWMRPDS IVKENGSDSR PCLFSGDANP
1760 1770 1780 1790 1800
SDVCQGRLGD CWFLSAVAVL TEVSRISEVI ITPEYNEEGI YTVRFCIQGE
1810 1820 1830 1840 1850
WVPVVIDDWI PCESPGKPAF ATSRKLNELW VSMVEKAYAK LHGSYEALEG
1860 1870 1880 1890 1900
GLVQDALVDL TGGAGEEIDL RSAQAQIDLA SGRLWSQLLR FKQEGFLLGA
1910 1920 1930 1940 1950
GSPSGSDVHV SSSGIVQGHA YSVLQVREVD GHRLVQIRNP WANEVEWNGP
1960 1970 1980 1990 2000
WSDSSPEWTD RMKHKLKHVP QSKEGIFWMS WQDFQIHFRS IYVCRVYPRE
2010 2020 2030 2040 2050
MRYSVNGQWR GYSAGGCQDY SSWHQNPQFR LRATGSDASL PIHVFITLTQ
2060 2070 2080 2090 2100
GVGFSRTTPG FRNYQSSHDS QLFYIGLRIL KTRGRRAAYN IFLHESVGGT
2110 2120 2130 2140 2150
DYVNSREISC EMVLDPDPKG YTIVPTTIHP GEEAPFVLSV FTKASIVLEA

L
Length:2,151
Mass (Da):238,264
Last modified:June 1, 2002 - v1
Checksum:i50D571D7446A5609
GO

Sequence cautioni

The sequence AAG51565 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY061803 mRNA. Translation: AAL38186.1.
AC027034 Genomic DNA. Translation: AAG51565.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33232.1.
CP002684 Genomic DNA. Translation: AEE33233.1.
CP002684 Genomic DNA. Translation: AEE33234.1.
CP002684 Genomic DNA. Translation: AEE33235.1.
AY050822 mRNA. Translation: AAK92757.1.
AY074514 mRNA. Translation: AAL67128.1.
PIRiG96595.
RefSeqiNP_175932.2. NM_104411.4. [Q8RVL2-1]
NP_850966.1. NM_180635.1. [Q8RVL2-1]
NP_850967.1. NM_180636.1. [Q8RVL2-1]
UniGeneiAt.17726.

Genome annotation databases

EnsemblPlantsiAT1G55350.1; AT1G55350.1; AT1G55350. [Q8RVL2-1]
AT1G55350.2; AT1G55350.2; AT1G55350. [Q8RVL2-1]
AT1G55350.3; AT1G55350.3; AT1G55350. [Q8RVL2-1]
AT1G55350.4; AT1G55350.4; AT1G55350. [Q8RVL2-1]
GeneIDi841981.
GrameneiAT1G55350.1; AT1G55350.1; AT1G55350.
AT1G55350.2; AT1G55350.2; AT1G55350.
AT1G55350.3; AT1G55350.3; AT1G55350.
AT1G55350.4; AT1G55350.4; AT1G55350.
KEGGiath:AT1G55350.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Web resourcesi

Seed defective Arabidopsis mutants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY061803 mRNA. Translation: AAL38186.1.
AC027034 Genomic DNA. Translation: AAG51565.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE33232.1.
CP002684 Genomic DNA. Translation: AEE33233.1.
CP002684 Genomic DNA. Translation: AEE33234.1.
CP002684 Genomic DNA. Translation: AEE33235.1.
AY050822 mRNA. Translation: AAK92757.1.
AY074514 mRNA. Translation: AAL67128.1.
PIRiG96595.
RefSeqiNP_175932.2. NM_104411.4. [Q8RVL2-1]
NP_850966.1. NM_180635.1. [Q8RVL2-1]
NP_850967.1. NM_180636.1. [Q8RVL2-1]
UniGeneiAt.17726.

3D structure databases

ProteinModelPortaliQ8RVL2.
SMRiQ8RVL2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi27206. 2 interactors.
IntActiQ8RVL2. 1 interactor.
STRINGi3702.AT1G55350.5.

Protein family/group databases

MEROPSiC02.019.

PTM databases

iPTMnetiQ8RVL2.

Proteomic databases

PaxDbiQ8RVL2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G55350.1; AT1G55350.1; AT1G55350. [Q8RVL2-1]
AT1G55350.2; AT1G55350.2; AT1G55350. [Q8RVL2-1]
AT1G55350.3; AT1G55350.3; AT1G55350. [Q8RVL2-1]
AT1G55350.4; AT1G55350.4; AT1G55350. [Q8RVL2-1]
GeneIDi841981.
GrameneiAT1G55350.1; AT1G55350.1; AT1G55350.
AT1G55350.2; AT1G55350.2; AT1G55350.
AT1G55350.3; AT1G55350.3; AT1G55350.
AT1G55350.4; AT1G55350.4; AT1G55350.
KEGGiath:AT1G55350.

Organism-specific databases

TAIRiAT1G55350.

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000030613.
PhylomeDBiQ8RVL2.

Miscellaneous databases

PROiQ8RVL2.

Gene expression databases

ExpressionAtlasiQ8RVL2. baseline and differential.
GenevisibleiQ8RVL2. AT.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
Gene3Di2.60.120.200. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR013320. ConA-like_dom.
IPR000169. Pept_cys_AS.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
[Graphical view]
SUPFAMiSSF49758. SSF49758. 1 hit.
SSF49899. SSF49899. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00139. THIOL_PROTEASE_CYS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEK1_ARATH
AccessioniPrimary (citable) accession number: Q8RVL2
Secondary accession number(s): Q8VXW6, Q949X8, Q9C8A6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 18, 2013
Last sequence update: June 1, 2002
Last modified: November 30, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Miscellaneous

Although homology to other calpains is high within the protease domain, the lack of calcium-binding sites suggests that this protein is a protease that may not be activated by calcium ions.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.