Q8RU95 (4CLL6_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
4-coumarate--CoA ligase-like 6
EC=6.2.1.-

Gene names

Name:	4CLL6
Ordered Locus Names:	Os01g0901600, LOC_Os01g67540
ORF Names:	B1065G12.10, P0551C06.10

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	598 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Domain	Both substrate-binding domains (SBD1 and SBD2) are involved in the substrate recognition, and are sufficient to confer the substrate specificity.
Sequence similarities	Belongs to the ATP-dependent AMP-binding enzyme family.
Sequence caution	The sequence BAB89961.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAB90528.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence BAD82770.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 598	598	4-coumarate--CoA ligase-like 6		PRO_0000351632
Regions
	Nucleotide binding	232 – 240	9	ATP By similarity
	Nucleotide binding	390 – 395	6	ATP By similarity
	Region	320 – 389	70	SBD1
	Region	390 – 454	65	SBD2
	Compositional bias	276 – 284	9	Poly-Pro
Sites
	Binding site	475	1	ATP By similarity
	Binding site	490	1	ATP By similarity
	Binding site	581	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8RU95 [UniParc]. Last modified October 14, 2008. Version 2. Checksum: 56B7C37D12A686CB	FASTA	598	63,258
	10 20 30 40 50 60 MSKRSPPPQP AHIPMAEQRW RPPYPYASSA AGGGGVDRRS RSGFCAATRT FHSLRSVGPL 70 80 90 100 110 120 PPEELPLTVA AYAFSLLSSA PPLVVAGRGP ALVDAATGIA VSYPAFVARV RFLAGGLWCS 130 140 150 160 170 180 LGLRPGDVAL VVSPSCLDVA VLYFALMSIG VVVSPANPAS TADEYAHQVR LSRPAIAFVA 190 200 210 220 230 240 PEVAARLPRH VSRVVIGSEV FDRLASASAA GGWAAPPAVA MKQPSTAALL YSSGTTGRVK 250 260 270 280 290 300 AVAITHRNLI AQISAYNAIR ETVAREAATD AGKGKPPPPS PSPPAAVTLF PLPLFHVMGF 310 320 330 340 350 360 GLLTRTISSG ETAVVMRRFD LAAAARAVER YRVTKLSAAP PVVVALTKSD EARRRDLSSL 370 380 390 400 410 420 VAIVVGGAPL GREVSQRFAT VFPSVQIVQS YGLTESTGPV ATMAGPEESA AYGSVGRLAP 430 440 450 460 470 480 RVQAKIVDTA TGEVLGPGRR GELWIRGPVV MKGYVGDPEA TAATITPDGW LKTGDLCYFN 490 500 510 520 530 540 EDGYLYVVDR LKELIKYKGY QVPPAELEHI LQSRPEIADA AVVPYPDEEA GQLPMAFVVR 550 560 570 580 590 QPGAYLTEQQ VMNCVAKHVA PYKKVRRVAF VNAIPKSPAG KILRRELVLQ AMASTSRL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed: 12447438] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Oryza sativa full length cDNA." The rice full-length cDNA consortium Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
[3]	"Genome-wide analysis of a land plant-specific acyl:coenzyme A synthetase (ACS) gene family in Arabidopsis, poplar, rice and Physcomitrella." de Azevedo Souza C., Barbazuk B., Ralph S.G., Bohlmann J., Hamberger B., Douglas C.J. New Phytol. 179:987-1003(2008) [PubMed: 18627494] [Abstract] Cited for: GENE FAMILY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP003313 Genomic DNA. Translation: BAB89961.1. Sequence problems. AP003791 Genomic DNA. Translation: BAB90528.1. Sequence problems. AP006757 Genomic DNA. Translation: BAD82770.1. Sequence problems. AK241420 mRNA. No translation available.
3D structure databases
HSSP	HSSP built from PDB template 1LCI based on UniProtKB P08659.
ProteinModelPortal	Q8RU95.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
NMPDR	fig|39947.1.peg.7272.
Organism-specific databases
Gramene	Q8RU95.
Phylogenomic databases
OMA	IQVPILY.
Family and domain databases
InterPro	IPR020845. AMP-binding_CS. IPR000873. AMP-dep_Synth/Lig. [Graphical view]
Pfam	PF00501. AMP-binding. 1 hit. [Graphical view]
PROSITE	PS00455. AMP_BINDING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

4CLL6_ORYSJ

Accession

Primary (citable) accession number: Q8RU95

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 14, 2008
Last sequence update:	October 14, 2008
Last modified:	September 21, 2011
This is version 46 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program