Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8RR56

- Q8RR56_9BACI

UniProt

Q8RR56 - Q8RR56_9BACI

Protein
Submitted name:

Kumamolisin

Gene

kscp

Organism
Bacillus sp. MN-32
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 58 (01 Oct 2014)
      Sequence version 2 (01 Jun 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi504 – 5041CalciumImported
    Metal bindingi505 – 5051Calcium; via carbonyl oxygenImported
    Metal bindingi522 – 5221Calcium; via carbonyl oxygenImported
    Metal bindingi524 – 5241Calcium; via carbonyl oxygenImported
    Metal bindingi526 – 5261CalciumImported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. serine-type endopeptidase activity Source: InterPro

    Keywords - Ligandi

    CalciumImported, Metal-bindingImported

    Enzyme and pathway databases

    BRENDAi3.4.21.B48. 275055.

    Protein family/group databases

    MEROPSiS53.004.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    KumamolisinImported
    Gene namesi
    Name:kscpImported
    OrganismiBacillus sp. MN-32Imported
    Taxonomic identifieri198803 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini189 – 552364kumamolisinImportedPRO_5000049828Add
    BLAST

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1GT9X-ray1.381/2189-545[»]
    1GTGX-ray2.301189-545[»]
    1GTJX-ray1.751/2189-545[»]
    1GTLX-ray2.801/2189-545[»]
    1T1EX-ray1.18A1-552[»]
    1T1GX-ray1.18A189-552[»]
    1T1IX-ray1.28A189-552[»]
    ProteinModelPortaliQ8RR56.
    SMRiQ8RR56. Positions 12-545.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8RR56.

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.200. 1 hit.
    InterProiIPR015366. Peptidase_S53_propep.
    IPR000209. Peptidase_S8/S53_dom.
    IPR009020. Prot_inh_propept.
    [Graphical view]
    PfamiPF00082. Peptidase_S8. 1 hit.
    PF09286. Pro-kuma_activ. 1 hit.
    [Graphical view]
    SMARTiSM00944. Pro-kuma_activ. 1 hit.
    [Graphical view]
    SUPFAMiSSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8RR56-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDMEKPWKE EEKREVLAGH ARRQAPQAVD KGPVTGDQRI SVTVVLRRQR    50
    GDELEAHVER QAALAPHARV HLEREAFAAS HGASLDDFAE IRKFAEAHGL 100
    TLDRAHVAAG TAVLSGPVDA VNQAFGVELR HFDHPDGSYR SYVGDVRVPA 150
    SIAPLIEAVF GLDTRPVARP HFRLRRRAEG EFEARSQSAA PTAYTPLDVA 200
    QAYQFPEGLD GQGQCIAIIE LGGGYDETSL AQYFASLGVS APQVVSVSVD 250
    GATNQPTGDP NGPDGEVELD IEVAGALAPG AKIAVYFAPN TDAGFLNAIT 300
    TAVHDPTHKP SIVSISWGGP EDSWAPASIA AMNRAFLDAA ALGVTVLAAA 350
    GDSGSTDGEQ DGLYHVDFPA ASPYVLACGG TRLVASAGRI ERETVWNDGP 400
    DGGSTGGGVS RIFPLPSWQE RANVPPSANP GAGSGRGVPD VAGNADPATG 450
    YEVVIDGETT VIGGTSAVAP LFAALVARIN QKLGKPVGYL NPTLYQLPPE 500
    VFHDITEGNN DIANRARIYQ AGPGWDPCTG LGSPIGIRLL QALLPSASQA 550
    QP 552
    Length:552
    Mass (Da):57,743
    Last modified:June 1, 2003 - v2
    Checksum:i7EA9586DD366835C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB070740 Genomic DNA. Translation: BAB85637.2.
    PIRiJC7833.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB070740 Genomic DNA. Translation: BAB85637.2 .
    PIRi JC7833.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1GT9 X-ray 1.38 1/2 189-545 [» ]
    1GTG X-ray 2.30 1 189-545 [» ]
    1GTJ X-ray 1.75 1/2 189-545 [» ]
    1GTL X-ray 2.80 1/2 189-545 [» ]
    1T1E X-ray 1.18 A 1-552 [» ]
    1T1G X-ray 1.18 A 189-552 [» ]
    1T1I X-ray 1.28 A 189-552 [» ]
    ProteinModelPortali Q8RR56.
    SMRi Q8RR56. Positions 12-545.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S53.004.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BRENDAi 3.4.21.B48. 275055.

    Miscellaneous databases

    EvolutionaryTracei Q8RR56.

    Family and domain databases

    Gene3Di 3.40.50.200. 1 hit.
    InterProi IPR015366. Peptidase_S53_propep.
    IPR000209. Peptidase_S8/S53_dom.
    IPR009020. Prot_inh_propept.
    [Graphical view ]
    Pfami PF00082. Peptidase_S8. 1 hit.
    PF09286. Pro-kuma_activ. 1 hit.
    [Graphical view ]
    SMARTi SM00944. Pro-kuma_activ. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52743. SSF52743. 1 hit.
    SSF54897. SSF54897. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "A CLN2-related and thermostable serine-carboxyl proteinase, kumamolysin: cloning, expression, and identification of catalytic serine residue."
      Oyama H., Hamada T., Ogasawara S., Uchida K., Murao S., Beyer B.B., Dunn M.B., Oda K.
      J. Biochem. 131:757-765(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MN-32Imported.
    2. "The 1.4 a crystal structure of kumamolysin: a thermostable serine-carboxyl-type proteinase."
      Comellas-Bigler M., Fuentes-Prior P., Maskos K., Huber R., Oyama H., Uchida K., Dunn B.M., Oda K., Bode W.
      Structure 10:865-876(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.38 ANGSTROMS) OF 189-545 IN COMPLEX WITH CALCIUM.
    3. "1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase."
      Comellas-Bigler M., Maskos K., Huber R., Oyama H., Oda K., Bode W.
      Structure 12:1313-1323(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.18 ANGSTROMS).

    Entry informationi

    Entry nameiQ8RR56_9BACI
    AccessioniPrimary (citable) accession number: Q8RR56
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2002
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 58 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3